| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P47156 | 728 | JHD2_YEAST Histone demethylase JHD2 OS=Saccha... | 75 | 0.00002 | 51.6 | 37 | 45 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0032453; F:histone demethylase activity (H3-K4 specific); IMP:SGD.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 32 | Q8WYB5 | 2073 | KAT6B_HUMAN Histone acetyltransferase KAT6B O... | 98 | 0.00003 | 51.2 | 30 | 42 | GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IDA:UniProtKB.::GO:0000786; C:nucleosome; NAS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006334; P:nucleosome assembly; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | Q8BRB7 | 1872 | KAT6B_MOUSE Histone acetyltransferase KAT6B O... | 98 | 0.00004 | 50.8 | 30 | 42 | GO:0070776; C:MOZ/MORF histone acetyltransferase complex; ISS:UniProtKB.::GO:0000786; C:nucleosome; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | O88491 | 2588 | NSD1_MOUSE Histone-lysine N-methyltransferase... | 53 | 2 | 35.4 | 32 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 35 | Q8WML3 | 1784 | KAT6B_MACFA Histone acetyltransferase KAT6B O... | 98 | 0.00005 | 50.8 | 30 | 42 | GO:0070776; C:MOZ/MORF histone acetyltransferase complex; ISS:UniProtKB.::GO:0000786; C:nucleosome; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 36 | Q96L73 | 2696 | NSD1_HUMAN Histone-lysine N-methyltransferase... | 53 | 5.9 | 34.3 | 30 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 37 | Q8C966 | 487 | PF21B_MOUSE PHD finger protein 21B OS=Mus mus... | 77 | 0.00008 | 49.7 | 27 | 44 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 38 | Q92794 | 2004 | KAT6A_HUMAN Histone acetyltransferase KAT6A O... | 53 | 0.0001 | 49.3 | 38 | 51 | GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IDA:UniProtKB.::GO:0000786; C:nucleosome; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; TAS:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 39 | Q96EK2 | 531 | PF21B_HUMAN PHD finger protein 21B OS=Homo sa... | 77 | 0.0002 | 48.5 | 26 | 43 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 40 | Q8BZ21 | 2003 | KAT6A_MOUSE Histone acetyltransferase KAT6A O... | 53 | 0.0002 | 48.5 | 38 | 51 | GO:0070776; C:MOZ/MORF histone acetyltransferase complex; ISS:UniProtKB.::GO:0000786; C:nucleosome; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; ISS:UniProtKB.::GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 41 | Q5TKR9 | 1998 | KAT6A_RAT Histone acetyltransferase KAT6A OS=... | 53 | 0.0002 | 48.5 | 38 | 51 | GO:0070776; C:MOZ/MORF histone acetyltransferase complex; ISS:UniProtKB.::GO:0000786; C:nucleosome; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; ISS:UniProtKB.::GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 42 | Q9UIG0 | 1483 | BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B OS=... | 55 | 0.0005 | 47.4 | 36 | 45 | GO:0071778; C:WINAC complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0035173; F:histone kinase activity; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0071884; F:vitamin D receptor activator activity; IMP:BHF-UCL.::GO:0042809; F:vitamin D receptor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0043044; P:ATP-dependent chromatin remodeling; IDA:BHF-UCL.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:BHF-UCL.::GO:0034725; P:DNA replication-dependent nucleosome disassembly; IMP:BHF-UCL.::GO:0006302; P:double-strand break repair; ISS:BHF-UCL.::GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; NAS:BHF-UCL. | 43 | Q3UXZ9 | 1690 | KDM5A_MOUSE Lysine-specific demethylase 5A OS... | 57 | 0.0005 | 47.4 | 32 | 49 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | Q9ULU4 | 1186 | PKCB1_HUMAN Protein kinase C-binding protein ... | 50 | 0.0005 | 47.4 | 40 | 52 | GO:0005634; C:nucleus; ISS:BHF-UCL. | | | | | | | | | | GO:0070491; F:repressing transcription factor binding; ISS:BHF-UCL.::GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 45 | Q8NEZ4 | 4911 | MLL3_HUMAN Histone-lysine N-methyltransferase... | 46 | 0.037 | 41.2 | 33 | 48 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 46 | Q9Z277 | 1479 | BAZ1B_MOUSE Tyrosine-protein kinase BAZ1B OS=... | 55 | 0.0006 | 47 | 36 | 45 | GO:0005721; C:centromeric heterochromatin; IDA:MGI.::GO:0000793; C:condensed chromosome; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0071884; F:vitamin D receptor activator activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:BHF-UCL.::GO:0006302; P:double-strand break repair; IMP:BHF-UCL.::GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 47 | Q8BRH4 | 4903 | MLL3_MOUSE Histone-lysine N-methyltransferase... | 46 | 0.051 | 40.8 | 33 | 48 | GO:0035097; C:histone methyltransferase complex; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 48 | Q9H930 | 580 | LY10L_HUMAN Nuclear body protein SP140-like p... | 52 | 0.0008 | 46.2 | 40 | 50 | GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 49 | P29375 | 1690 | KDM5A_HUMAN Lysine-specific demethylase 5A OS... | 57 | 0.002 | 45.8 | 30 | 49 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 50 | O14686 | 5537 | MLL2_HUMAN Histone-lysine N-methyltransferase... | 48 | 0.005 | 44.3 | 35 | 48 | GO:0035097; C:histone methyltransferase complex; IPI:MGI. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0001555; P:oocyte growth; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q80Y84 | 1544 | KDM5B_MOUSE Lysine-specific demethylase 5B OS... | 90 | 0.002 | 45.4 | 27 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | Q5F3R2 | 1522 | KDM5B_CHICK Lysine-specific demethylase 5B OS... | 145 | 4.5 | 34.3 | 27 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 53 | Q9HB58 | 689 | SP110_HUMAN Sp110 nuclear body protein OS=Hom... | 51 | 0.003 | 44.7 | 37 | 49 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 54 | Q9HDV4 | 1513 | LID2_SCHPO Lid2 complex component lid2 OS=Sch... | 65 | 0.003 | 44.7 | 28 | 48 | GO:0048189; C:Lid2 complex; IDA:PomBase.::GO:0031934; C:mating-type region heterochromatin; IDA:PomBase.::GO:0031618; C:nuclear centromeric heterochromatin; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:PomBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0031507; P:heterochromatin assembly; IMP:PomBase.::GO:0051567; P:histone H3-K9 methylation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0034630; P:RITS complex localization; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | Q9UGL1 | 1544 | KDM5B_HUMAN Lysine-specific demethylase 5B OS... | 171 | 0.003 | 44.7 | 25 | 40 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:GDB.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:GDB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 56 | Q96T88 | 793 | UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1... | 46 | 0.004 | 44.3 | 43 | 50 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IEP:BHF-UCL.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.::GO:2000373; P:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; IC:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | Q13342 | 867 | LY10_HUMAN Nuclear body protein SP140 OS=Homo... | 52 | 0.004 | 44.3 | 40 | 48 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005635; C:nuclear envelope; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; TAS:ProtInc. | 58 | Q30DN6 | 1545 | KDM5D_CANFA Lysine-specific demethylase 5D OS... | 95 | 0.005 | 44.3 | 25 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 59 | Q6PDK2 | 5588 | MLL2_MOUSE Histone-lysine N-methyltransferase... | 48 | 0.005 | 44.3 | 35 | 48 | | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IMP:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001555; P:oocyte growth; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 60 | Q9SGH2 | 2176 | MBD9_ARATH Methyl-CpG-binding domain-containi... | 50 | 0.043 | 41.2 | 30 | 46 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0042393; F:histone binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IMP:UniProtKB.::GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.::GO:0048573; P:photoperiodism, flowering; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:TAIR.::GO:0010223; P:secondary shoot formation; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 61 | Q62240 | 1548 | KDM5D_MOUSE Lysine-specific demethylase 5D OS... | 111 | 0.007 | 43.5 | 27 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. |
