rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12458 | 312 | YPR1_YEAST Putative reductase 1 OS=Saccharomy... | 201 | 2e-60 | 197 | 46 | 67 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:SGD.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; IDA:SGD. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; IDA:SGD.::GO:0042843; P:D-xylose catabolic process; IDA:SGD. | 2 | P14065 | 312 | GCY_YEAST Protein GCY OS=Saccharomyces cerevi... | 201 | 4e-59 | 194 | 48 | 67 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:SGD.::GO:0003729; F:mRNA binding; IDA:SGD. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; IDA:SGD.::GO:0042843; P:D-xylose catabolic process; IDA:SGD. | 3 | P80276 | 316 | ALDR_PIG Aldose reductase OS=Sus scrofa (Pig)... | 174 | 5e-36 | 133 | 41 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 4 | P82125 | 301 | AKCL2_PIG 1,5-anhydro-D-fructose reductase OS... | 168 | 5e-36 | 133 | 42 | 60 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 5 | P07943 | 316 | ALDR_RAT Aldose reductase OS=Rattus norvegicu... | 175 | 9e-36 | 132 | 41 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:RGD. | | | | | | | | | | GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.::GO:0006061; P:sorbitol biosynthetic process; IMP:RGD.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD. | 6 | P27800 | 323 | ALDX_SPOSA Aldehyde reductase 1 OS=Sporobolom... | 210 | 2e-34 | 129 | 39 | 54 | GO:0005623; C:cell; IDA:UniProtKB. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB. | | | | | | | | | | | 7 | Q9DCT1 | 301 | AKCL2_MOUSE 1,5-anhydro-D-fructose reductase ... | 171 | 3e-34 | 128 | 37 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 8 | O08782 | 316 | ALD2_CRIGR Aldose reductase-related protein 2... | 193 | 3e-34 | 129 | 38 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 9 | P16116 | 315 | ALDR_BOVIN Aldose reductase OS=Bos taurus (Bo... | 184 | 4e-34 | 128 | 38 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 10 | P45376 | 316 | ALDR_MOUSE Aldose reductase OS=Mus musculus (... | 175 | 4e-34 | 128 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI. | | | | | | | | | | | 11 | P45377 | 316 | ALD2_MOUSE Aldose reductase-related protein 2... | 177 | 4e-34 | 128 | 39 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 12 | Q5U1Y4 | 301 | AKCL2_RAT 1,5-anhydro-D-fructose reductase OS... | 173 | 2e-33 | 126 | 40 | 60 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 13 | P38115 | 344 | ARA1_YEAST D-arabinose dehydrogenase [NAD(P)+... | 184 | 2e-32 | 124 | 38 | 59 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:SGD.::GO:0045290; F:D-arabinose 1-dehydrogenase [NAD(P)+ activity; IDA:SGD. | | | | | | | | | | GO:0044262; P:cellular carbohydrate metabolic process; IMP:SGD.] | 14 | P70694 | 323 | DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 ... | 195 | 2e-32 | 124 | 38 | 59 | | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IDA:MGI. | 15 | Q95JH6 | 323 | AK1C1_MACFU Aldo-keto reductase family 1 memb... | 190 | 8e-32 | 122 | 37 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 16 | P15122 | 316 | ALDR_RABIT Aldose reductase OS=Oryctolagus cu... | 174 | 8e-32 | 122 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 17 | Q6W8P9 | 323 | AK1CO_HORSE Aldo-keto reductase family 1 memb... | 210 | 1e-31 | 122 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 18 | O60218 | 316 | AK1BA_HUMAN Aldo-keto reductase family 1 memb... | 177 | 1e-31 | 122 | 37 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:ProtInc. | 19 | P15121 | 316 | ALDR_HUMAN Aldose reductase OS=Homo sapiens (... | 174 | 1e-31 | 121 | 37 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.::GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.::GO:0006950; P:response to stress; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 20 | Q95JH7 | 323 | AK1C1_MACFA Aldo-keto reductase family 1 memb... | 190 | 3e-31 | 121 | 37 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 21 | Q8VCX1 | 325 | AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen... | 196 | 6e-31 | 120 | 33 | 58 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 22 | Q6AZW2 | 324 | A1A1A_DANRE Alcohol dehydrogenase [NADP(+)] A... | 179 | 1e-30 | 119 | 39 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 23 | Q54NZ7 | 311 | ALRB_DICDI Aldose reductase B OS=Dictyosteliu... | 182 | 1e-30 | 119 | 39 | 57 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase. | | | | | | | | | | | 24 | Q9TV64 | 326 | AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen... | 148 | 2e-30 | 119 | 39 | 61 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 25 | P52897 | 323 | PGFS2_BOVIN Prostaglandin F synthase 2 OS=Bos... | 177 | 2e-30 | 119 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 26 | P05980 | 323 | PGFS1_BOVIN Prostaglandin F synthase 1 OS=Bos... | 177 | 2e-30 | 119 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 27 | Q5R5D5 | 325 | AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O... | 170 | 2e-30 | 118 | 39 | 57 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 28 | P52898 | 323 | DDBX_BOVIN Dihydrodiol dehydrogenase 3 OS=Bos... | 177 | 3e-30 | 118 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 29 | Q10494 | 321 | YDG7_SCHPO Uncharacterized oxidoreductase C26... | 185 | 3e-30 | 118 | 37 | 58 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 30 | Q0CUL0 | 320 | XYL1_ASPTN Probable NAD(P)H-dependent D-xylos... | 178 | 4e-30 | 117 | 39 | 58 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 31 | P21300 | 316 | ALD1_MOUSE Aldose reductase-related protein 1... | 174 | 5e-30 | 117 | 38 | 59 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:MGI. |