rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P21300 | 316 | ALD1_MOUSE Aldose reductase-related protein 1... | 174 | 5e-30 | 117 | 38 | 59 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:MGI. | 32 | Q1XAA8 | 322 | AK1CN_HORSE Aldo-keto reductase family 1 memb... | 176 | 5e-30 | 117 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 33 | P17516 | 323 | AK1C4_HUMAN Aldo-keto reductase family 1 memb... | 177 | 7e-30 | 117 | 37 | 58 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB. | 34 | P51857 | 326 | AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen... | 174 | 1e-29 | 117 | 34 | 59 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB. | 35 | P14550 | 325 | AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O... | 196 | 1e-29 | 116 | 36 | 55 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc. | 36 | Q568L5 | 324 | A1A1B_DANRE Alcohol dehydrogenase [NADP(+)] B... | 188 | 2e-29 | 116 | 37 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 37 | P80508 | 323 | PE2R_RABIT Prostaglandin-E(2) 9-reductase OS=... | 175 | 2e-29 | 116 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 38 | Q96JD6 | 320 | AKCL2_HUMAN 1,5-anhydro-D-fructose reductase ... | 140 | 2e-29 | 115 | 39 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 39 | Q5REQ0 | 323 | AK1C1_PONAB Aldo-keto reductase family 1 memb... | 177 | 2e-29 | 115 | 36 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 40 | P52895 | 323 | AK1C2_HUMAN Aldo-keto reductase family 1 memb... | 195 | 3e-29 | 115 | 34 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB. | 41 | Q04828 | 323 | AK1C1_HUMAN Aldo-keto reductase family 1 memb... | 195 | 4e-29 | 115 | 34 | 56 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.::GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB. | 42 | P17264 | 324 | CRO_LITCT Rho crystallin OS=Lithobates catesb... | 175 | 4e-29 | 115 | 37 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 43 | P02532 | 324 | CRO_RANTE Rho crystallin OS=Rana temporaria (... | 175 | 5e-29 | 115 | 37 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 44 | Q8K023 | 323 | AKC1H_MOUSE Aldo-keto reductase family 1 memb... | 175 | 5e-29 | 115 | 37 | 56 | | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0007567; P:parturition; IMP:MGI.::GO:0006709; P:progesterone catabolic process; IDA:MGI. | 45 | C9JRZ8 | 344 | AK1BF_HUMAN Aldo-keto reductase family 1 memb... | 177 | 6e-29 | 115 | 35 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 46 | A0QV10 | 275 | Y2408_MYCS2 Uncharacterized oxidoreductase MS... | 166 | 8e-29 | 113 | 39 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | Q4R802 | 320 | AKCL2_MACFA 1,5-anhydro-D-fructose reductase ... | 140 | 1e-28 | 114 | 39 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 48 | P51635 | 325 | AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=... | 170 | 1e-28 | 113 | 37 | 58 | | | | | | | | | | | | | | | | | | | | | | 49 | Q6IMN8 | 297 | ALRA_DICDI Aldose reductase A OS=Dictyosteliu... | 180 | 2e-28 | 113 | 36 | 56 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0042593; P:glucose homeostasis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IMP:dictyBase. | 50 | Q91WR5 | 323 | AK1CL_MOUSE Aldo-keto reductase family 1 memb... | 175 | 2e-28 | 113 | 35 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033764; F:steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IDA:MGI. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 51 | Q5ZK84 | 327 | AK1A1_CHICK Alcohol dehydrogenase [NADP(+)] O... | 177 | 2e-28 | 113 | 37 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 52 | Q95JH4 | 323 | AK1C4_MACFU Aldo-keto reductase family 1 memb... | 177 | 3e-28 | 113 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 53 | Q95JH5 | 323 | AK1C4_MACFA Aldo-keto reductase family 1 memb... | 177 | 3e-28 | 112 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 54 | Q55FL3 | 321 | ALRC_DICDI Aldose reductase C OS=Dictyosteliu... | 202 | 3e-28 | 112 | 35 | 52 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; ISS:dictyBase. | 55 | P42330 | 323 | AK1C3_HUMAN Aldo-keto reductase family 1 memb... | 206 | 3e-28 | 112 | 34 | 53 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB. | 56 | Q3ZCJ2 | 325 | AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O... | 196 | 4e-28 | 112 | 36 | 53 | | | | | | | | | | | | | | | | | | | | | | 57 | P50578 | 325 | AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=... | 198 | 5e-28 | 112 | 36 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 58 | Q5R7C9 | 323 | AK1C3_PONAB Aldo-keto reductase family 1 memb... | 206 | 7e-28 | 111 | 34 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB. | 59 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 175 | 1e-27 | 111 | 34 | 55 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. | 60 | Q6GMC7 | 327 | AK1A1_XENLA Alcohol dehydrogenase [NADP(+)] O... | 170 | 1e-27 | 110 | 38 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 61 | Q28FD1 | 327 | AK1A1_XENTR Alcohol dehydrogenase [NADP(+)] O... | 170 | 2e-27 | 110 | 37 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | |