| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q9VDG2 | 625 | RLIP_DROME RalA-binding protein 1 OS=Drosophi... | 172 | 0.001 | 47.4 | 24 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:FlyBase. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 212 | B2RWW0 | 714 | TAGAP_MOUSE T-cell activation Rho GTPase-acti... | 202 | 0.002 | 47 | 27 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 213 | Q14CB8 | 494 | RHG19_HUMAN Rho GTPase-activating protein 19 ... | 209 | 0.004 | 45.4 | 22 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 214 | Q9D300 | 466 | RGF1C_MOUSE Ras-GEF domain-containing family ... | 102 | 0.006 | 44.7 | 30 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 215 | Q63787 | 724 | P85A_RAT Phosphatidylinositol 3-kinase regula... | 173 | 0.009 | 44.7 | 26 | 45 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:RGD.::GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IPI:RGD.::GO:0005516; F:calmodulin binding; IPI:RGD.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD. | | | | | | | | | | GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0010459; P:negative regulation of heart rate; IMP:RGD.::GO:0045861; P:negative regulation of proteolysis; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009750; P:response to fructose stimulus; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0010040; P:response to iron(II) ion; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0001878; P:response to yeast; IEP:RGD. | 216 | Q55DK5 | 1337 | MGP3_DICDI Mental retardation GTPase activati... | 138 | 0.012 | 44.3 | 28 | 46 | GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 217 | Q8BRH3 | 494 | RHG19_MOUSE Rho GTPase-activating protein 19 ... | 174 | 0.016 | 43.5 | 24 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 218 | Q60695 | 768 | RGL1_MOUSE Ral guanine nucleotide dissociatio... | 132 | 0.021 | 43.5 | 28 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 219 | Q12128 | 409 | BAG7_YEAST Rho-GTPase-activating protein BAG7... | 157 | 0.031 | 42.4 | 23 | 44 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 220 | Q02342 | 1095 | CDC25_LACKL Cell division control protein 25 ... | 57 | 0.031 | 43.1 | 37 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 221 | Q95KH6 | 466 | RGF1C_MACFA Ras-GEF domain-containing family ... | 102 | 0.05 | 42 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 222 | Q9P3B1 | 374 | YIL2_SCHPO Putative Rho GTPase-activating pro... | 145 | 0.054 | 41.6 | 25 | 45 | GO:0005794; C:Golgi apparatus; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 223 | Q8N431 | 466 | RGF1C_HUMAN Ras-GEF domain-containing family ... | 102 | 0.059 | 41.6 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 224 | O15211 | 777 | RGL2_HUMAN Ral guanine nucleotide dissociatio... | 196 | 0.059 | 42 | 29 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 225 | Q3UYI5 | 709 | RGL3_MOUSE Ral guanine nucleotide dissociatio... | 66 | 0.067 | 41.6 | 32 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0017016; F:Ras GTPase binding; IDA:MGI. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:MGI. | 226 | Q8SSQ0 | 1721 | GEFR_DICDI Ras guanine nucleotide exchange fa... | 56 | 2.6 | 36.6 | 30 | 64 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:dictyBase. | | | | | | | | | | GO:0007265; P:Ras protein signal transduction; IDA:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 227 | Q9NZL6 | 768 | RGL1_HUMAN Ral guanine nucleotide dissociatio... | 127 | 0.079 | 41.6 | 28 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 228 | Q8IZJ4 | 473 | RGDSR_HUMAN Ral-GDS-related protein OS=Homo s... | 147 | 0.084 | 41.2 | 27 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 229 | Q86L99 | 1523 | GACHH_DICDI Rho GTPase-activating protein gac... | 133 | 0.12 | 41.2 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 230 | P04821 | 1589 | CDC25_YEAST Cell division control protein 25 ... | 56 | 0.14 | 40.8 | 38 | 55 | GO:0005829; C:cytosol; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IMP:SGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0007089; P:traversing start control point of mitotic cell cycle; IMP:SGD. | 231 | Q6P112 | 804 | RGL1_DANRE Ral guanine nucleotide dissociatio... | 56 | 0.17 | 40.4 | 36 | 61 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 232 | Q8IS11 | 944 | GEFO_DICDI Ras guanine nucleotide exchange fa... | 66 | 0.28 | 39.7 | 36 | 58 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 233 | Q03385 | 852 | GNDS_MOUSE Ral guanine nucleotide dissociatio... | 126 | 0.29 | 39.7 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 234 | Q3MIN7 | 710 | RGL3_HUMAN Ral guanine nucleotide dissociatio... | 57 | 0.32 | 39.7 | 35 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 235 | Q5TJE5 | 780 | RGL2_CANFA Ral guanine nucleotide dissociatio... | 72 | 0.32 | 39.7 | 32 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 236 | Q74ZH7 | 1013 | BEM3_ASHGO GTPase-activating protein BEM3 OS=... | 300 | 0.39 | 39.3 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 237 | Q5F3G0 | 495 | RHG19_CHICK Rho GTPase-activating protein 19 ... | 208 | 0.5 | 38.9 | 23 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 238 | P0CF34 | 1048 | YL017_YEAST Putative guanine nucleotide excha... | 56 | 0.64 | 38.5 | 38 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 239 | Q61193 | 778 | RGL2_MOUSE Ral guanine nucleotide dissociatio... | 185 | 0.67 | 38.5 | 26 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 240 | C8ZCV7 | 1252 | SDC25_YEAS8 Guanine nucleotide exchange facto... | 57 | 0.98 | 38.1 | 37 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 241 | P0CF32 | 1253 | SDC25_YEASX Guanine nucleotide exchange facto... | 57 | 1 | 38.1 | 37 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
