| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40851 | 1208 | AXL1_YEAST Putative protease AXL1 OS=Saccharo... | 1039 | 1e-71 | 263 | 25 | 44 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007120; P:axial cellular bud site selection; IMP:SGD.::GO:0007323; P:peptide pheromone maturation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | P35559 | 1019 | IDE_RAT Insulin-degrading enzyme OS=Rattus no... | 220 | 4e-38 | 158 | 39 | 59 | GO:0009986; C:cell surface; IDA:RGD.::GO:0031597; C:cytosolic proteasome complex; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005782; C:peroxisomal matrix; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IPI:RGD.::GO:0031626; F:beta-endorphin binding; IMP:RGD.::GO:0043559; F:insulin binding; IMP:RGD.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0042447; P:hormone catabolic process; IDA:RGD.::GO:0045861; P:negative regulation of proteolysis; IDA:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:RGD. | 3 | O14077 | 969 | MU138_SCHPO Putative zinc protease mug138 OS=... | 877 | 6e-38 | 157 | 22 | 41 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase. | 4 | Q9JHR7 | 1019 | IDE_MOUSE Insulin-degrading enzyme OS=Mus mus... | 220 | 2e-37 | 155 | 38 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 5 | Q24K02 | 1019 | IDE_BOVIN Insulin-degrading enzyme OS=Bos tau... | 220 | 3e-37 | 155 | 38 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | P14735 | 1019 | IDE_HUMAN Insulin-degrading enzyme OS=Homo sa... | 220 | 5e-37 | 154 | 38 | 59 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 7 | P22817 | 990 | IDE_DROME Insulin-degrading enzyme OS=Drosoph... | 137 | 0.17 | 39.7 | 24 | 48 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 8 | Q06010 | 1027 | STE23_YEAST A-factor-processing enzyme OS=Sac... | 343 | 1e-35 | 150 | 29 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007323; P:peptide pheromone maturation; IGI:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 9 | O22941 | 970 | PXM16_ARATH Zinc-metallopeptidase, peroxisoma... | 215 | 1e-32 | 140 | 34 | 57 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q5R4H6 | 1152 | NRDC_PONAB Nardilysin OS=Pongo abelii (Sumatr... | 892 | 2e-31 | 137 | 22 | 40 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | O43847 | 1150 | NRDC_HUMAN Nardilysin OS=Homo sapiens (Human)... | 890 | 3e-31 | 136 | 21 | 40 | GO:0009986; C:cell surface; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB. | | | | | | | | | | GO:0048408; F:epidermal growth factor binding; TAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007528; P:neuromuscular junction development; TAS:ProtInc.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL. | 12 | P47245 | 1161 | NRDC_RAT Nardilysin OS=Rattus norvegicus (Rat... | 882 | 6e-31 | 135 | 21 | 40 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | Q8BHG1 | 1161 | NRDC_MOUSE Nardilysin OS=Mus musculus (Mouse)... | 886 | 6e-30 | 132 | 22 | 39 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | P42789 | 596 | SDP_EIMBO Sporozoite developmental protein OS... | 396 | 9e-29 | 126 | 27 | 46 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 15 | Q10040 | 856 | YQA4_CAEEL Putative zinc protease C28F5.4 OS=... | 349 | 1e-27 | 124 | 27 | 48 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | Q54JQ2 | 962 | IDE_DICDI Insulin-degrading enzyme homolog OS... | 219 | 2e-22 | 107 | 30 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | Q8X6M8 | 962 | PTRA_ECO57 Protease 3 OS=Escherichia coli O15... | 332 | 0.019 | 42.7 | 19 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 18 | P05458 | 962 | PTRA_ECOLI Protease 3 OS=Escherichia coli (st... | 332 | 0.02 | 42.7 | 19 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:EcoCyc. | 19 | Q83QC3 | 962 | PTRA_SHIFL Protease 3 OS=Shigella flexneri. G... | 332 | 0.02 | 42.7 | 19 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 20 | Q8CVS2 | 962 | PTRA_ECOL6 Protease 3 OS=Escherichia coli O6:... | 332 | 0.009 | 43.9 | 19 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | Q9I2D2 | 775 | PQQF_PSEAE Coenzyme PQQ synthesis protein F O... | 206 | 1e-17 | 91.7 | 27 | 43 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 22 | Q8ZMB5 | 962 | PTRA_SALTY Protease 3 OS=Salmonella typhimuri... | 319 | 0.17 | 39.7 | 18 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 23 | Q8Z418 | 962 | PTRA_SALTI Protease 3 OS=Salmonella typhi. GN... | 319 | 0.16 | 39.7 | 18 | 37 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 24 | Q88QV3 | 766 | PQQF_PSEPK Coenzyme PQQ synthesis protein F O... | 213 | 0.0000000000002 | 78.6 | 24 | 45 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 25 | Q4W6B5 | 469 | MPPB_DICDI Mitochondrial-processing peptidase... | 294 | 0.000000000008 | 72.4 | 22 | 44 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0017087; C:mitochondrial processing peptidase complex; ISS:dictyBase.::GO:0031982; C:vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; ISS:dictyBase.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:dictyBase.::GO:0006627; P:protein processing involved in protein targeting to mitochondrion; ISS:dictyBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 26 | P55174 | 829 | PQQF_PSEFL Coenzyme PQQ synthesis protein F O... | 226 | 0.00000000001 | 72.4 | 23 | 46 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 27 | P27508 | 761 | PQQF_KLEPN Coenzyme PQQ synthesis protein F O... | 201 | 0.00000000002 | 71.6 | 24 | 44 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 28 | Q88A79 | 779 | PQQF_PSESM Coenzyme PQQ synthesis protein F O... | 221 | 0.00000000004 | 70.9 | 23 | 43 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-KW. | 29 | P55679 | 512 | Y4WA_RHISN Uncharacterized zinc protease y4wA... | 92 | 0.000000003 | 64.3 | 33 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | Q42290 | 531 | MPPB_ARATH Probable mitochondrial-processing ... | 232 | 0.00000008 | 59.7 | 23 | 44 | GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005758; C:mitochondrial intermembrane space; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IDA:TAIR.::GO:0005741; C:mitochondrial outer membrane; IDA:TAIR.::GO:0005750; C:mitochondrial respiratory chain complex III; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | Q04805 | 409 | YMXG_BACSU Uncharacterized zinc protease ymxG... | 192 | 0.000001 | 55.5 | 23 | 44 | | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
