rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q6P2Q9 | 2335 | PRP8_HUMAN Pre-mRNA-processing-splicing facto... | 555 | 0 | 587 | 55 | 70 | GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005682; C:U5 snRNP; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB. | 2 | Q99PV0 | 2335 | PRP8_MOUSE Pre-mRNA-processing-splicing facto... | 555 | 0 | 587 | 55 | 70 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro. | 3 | Q8T295 | 2327 | PRP8_DICDI Pre-mRNA-processing-splicing facto... | 539 | 0 | 583 | 56 | 73 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0005682; C:U5 snRNP; ISS:dictyBase. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro. | 4 | P34369 | 2329 | PRP8_CAEEL Pre-mRNA-splicing factor 8 homolog... | 537 | 3e-180 | 570 | 55 | 71 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 5 | P33334 | 2413 | PRP8_YEAST Pre-mRNA-splicing factor 8 OS=Sacc... | 525 | 1e-178 | 566 | 55 | 71 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0030623; F:U5 snRNA binding; IDA:SGD. | | | | | | | | | | GO:0000244; P:assembly of spliceosomal tri-snRNP; IMP:SGD.::GO:0000389; P:nuclear mRNA 3'-splice site recognition; IMP:SGD. | 6 | O14187 | 2363 | SPP42_SCHPO Pre-mRNA-splicing factor spp42 OS... | 562 | 1e-159 | 512 | 49 | 66 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005682; C:U5 snRNP; ISS:PomBase. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000393; P:spliceosomal conformational changes to generate catalytic conformation; IGI:PomBase. | 7 | P12255 | 3590 | FHAB_BORPE Filamentous hemagglutinin OS=Borde... | 66 | 2.8 | 35 | 27 | 42 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 8 | P19835 | 753 | CEL_HUMAN Bile salt-activated lipase OS=Homo ... | 58 | 9.4 | 33.1 | 47 | 57 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005615; C:extracellular space; IBA:RefGenome. | | | | | | | | | | GO:0047372; F:acylglycerol lipase activity; TAS:Reactome.::GO:0004091; F:carboxylesterase activity; IBA:RefGenome.::GO:0008201; F:heparin binding; NAS:UniProtKB.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004771; F:sterol esterase activity; NAS:UniProtKB.::GO:0004806; F:triglyceride lipase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0009062; P:fatty acid catabolic process; NAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; NAS:UniProtKB.::GO:0044258; P:intestinal lipid catabolic process; NAS:UniProtKB.::GO:0030157; P:pancreatic juice secretion; IDA:UniProtKB.::GO:0018350; P:protein esterification; NAS:UniProtKB.::GO:0006641; P:triglyceride metabolic process; IC:UniProtKB. | 9 | A6X919 | 746 | D19L1_MOUSE Protein dpy-19 homolog 1 OS=Mus m... | 89 | 0.27 | 38.1 | 31 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 10 | Q6KC79 | 2804 | NIPBL_HUMAN Nipped-B-like protein OS=Homo sap... | 76 | 0.6 | 37 | 29 | 42 | GO:0032116; C:SMC loading complex; IDA:UniProtKB. | | | | | | | | | | GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:BHF-UCL.::GO:0034613; P:cellular protein localization; IMP:UniProtKB.::GO:0071481; P:cellular response to X-ray; IMP:UniProtKB.::GO:0050890; P:cognition; IMP:BHF-UCL.::GO:0048589; P:developmental growth; IMP:BHF-UCL.::GO:0042471; P:ear morphogenesis; IMP:BHF-UCL.::GO:0035117; P:embryonic arm morphogenesis; IMP:BHF-UCL.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:BHF-UCL.::GO:0035261; P:external genitalia morphogenesis; IMP:BHF-UCL.::GO:0048592; P:eye morphogenesis; IMP:BHF-UCL.::GO:0060325; P:face morphogenesis; IMP:BHF-UCL.::GO:0061010; P:gall bladder development; IMP:BHF-UCL.::GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0001656; P:metanephros development; NAS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IDA:BHF-UCL.::GO:0048638; P:regulation of developmental growth; IMP:BHF-UCL.::GO:0045995; P:regulation of embryonic development; IMP:BHF-UCL.::GO:0042634; P:regulation of hair cycle; IMP:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.::GO:0061038; P:uterus morphogenesis; IMP:BHF-UCL. | 11 | Q8IZP9 | 1017 | GPR64_HUMAN G-protein coupled receptor 64 OS=... | 128 | 0.81 | 36.6 | 27 | 41 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 12 | A6VFU7 | 555 | SYE_METM7 Glutamate--tRNA ligase OS=Methanoco... | 48 | 1.5 | 35.4 | 40 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004818; F:glutamate-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:InterPro. | 13 | Q9ESF1 | 1997 | OTOF_MOUSE Otoferlin OS=Mus musculus (Mouse).... | 130 | 2.1 | 35.4 | 25 | 44 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; IDA:UniProtKB. | 14 | Q9HC10 | 1997 | OTOF_HUMAN Otoferlin OS=Homo sapiens (Human).... | 130 | 2.3 | 35.4 | 25 | 44 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:ProtInc.::GO:0007605; P:sensory perception of sound; TAS:ProtInc.::GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB. | 15 | Q9ERC5 | 1993 | OTOF_RAT Otoferlin OS=Rattus norvegicus (Rat)... | 173 | 2.4 | 35 | 24 | 39 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB. | 16 | P89459 | 3122 | DEN_HHV2H Deneddylase UL36 OS=2). GN=UL36 ... | 94 | 3.1 | 34.7 | 31 | 38 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | O95613 | 3336 | PCNT_HUMAN Pericentrin OS=Homo sapiens (Human... | 67 | 3.1 | 34.7 | 34 | 40 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042384; P:cilium assembly; IDA:MGI.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome. | 18 | Q5VUA4 | 2279 | ZN318_HUMAN Zinc finger protein 318 OS=Homo s... | 54 | 3.9 | 34.7 | 43 | 46 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q96AW1 | 172 | VOPP1_HUMAN Vesicular, overexpressed in cance... | 60 | 4.8 | 33.1 | 35 | 38 | GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB.::GO:0005768; C:endosome; IDA:LIFEdb.::GO:0031301; C:integral to organelle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q9XXV8 | 858 | MYOK_DICDI Myosin-K heavy chain OS=Dictyostel... | 39 | 5.6 | 33.9 | 49 | 54 | GO:0032009; C:early phagosome; IDA:dictyBase.::GO:0070685; C:macropinocytic cup; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0001891; C:phagocytic cup; IDA:dictyBase.::GO:0001726; C:ruffle; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005522; F:profilin binding; IPI:dictyBase. | | | | | | | | | | GO:0033109; P:cortical actin cytoskeleton stabilization; IMP:dictyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:dictyBase.::GO:2000147; P:positive regulation of cell motility; IMP:dictyBase.::GO:0050766; P:positive regulation of phagocytosis; IMP:dictyBase. | 21 | Q5RDG5 | 172 | VOPP1_PONAB Vesicular, overexpressed in cance... | 60 | 5.6 | 32.7 | 35 | 38 | GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0031301; C:integral to organelle membrane; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | P81299 | 1063 | CDC14_CAEEL Probable tyrosine-protein phospha... | 205 | 6.7 | 33.5 | 22 | 41 | GO:0000235; C:astral microtubule; IDA:WormBase.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0030496; C:midbody; IDA:WormBase.::GO:0005730; C:nucleolus; IDA:WormBase.::GO:0051233; C:spindle midzone; IDA:WormBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0071850; P:mitotic cell cycle arrest; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0060284; P:regulation of cell development; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase. | 23 | Q99NH0 | 2603 | ANR17_MOUSE Ankyrin repeat domain-containing ... | 113 | 8.9 | 33.5 | 25 | 35 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007492; P:endoderm development; TAS:MGI. |