rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P43556 | 714 | RGD2_YEAST Rho-GTPase-activating protein RGD2... | 726 | 7e-144 | 447 | 37 | 57 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 2 | Q09697 | 777 | RGA8_SCHPO Rho-GTPase-activating protein 8 OS... | 780 | 3e-121 | 390 | 32 | 53 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IGI:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 3 | Q9UUJ3 | 670 | RGA9_SCHPO Probable Rho-GTPase-activating pro... | 731 | 6e-25 | 114 | 22 | 43 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 4 | Q03070 | 295 | CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ... | 139 | 0.00000005 | 58.9 | 32 | 50 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 5 | P38339 | 666 | RGD1_YEAST RHO GTPase-activating protein RGD1... | 222 | 0.00000008 | 59.7 | 28 | 45 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD. | 6 | Q80XD1 | 332 | CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo... | 139 | 0.0000001 | 58.2 | 31 | 50 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 7 | P52757 | 468 | CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu... | 139 | 0.0000002 | 58.2 | 31 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 8 | Q8C0D4 | 838 | RHG12_MOUSE Rho GTPase-activating protein 12 ... | 194 | 0.0000009 | 56.2 | 23 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 9 | Q8IWW6 | 846 | RHG12_HUMAN Rho GTPase-activating protein 12 ... | 194 | 0.000001 | 55.8 | 23 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 10 | Q9BE31 | 847 | RHG12_MACFA Rho GTPase-activating protein 12 ... | 194 | 0.000002 | 55.5 | 22 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 11 | Q6AYC5 | 482 | RHG15_RAT Rho GTPase-activating protein 15 OS... | 204 | 0.00001 | 52.4 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 12 | Q5ZMM3 | 475 | RHG15_CHICK Rho GTPase-activating protein 15 ... | 204 | 0.00001 | 52 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 13 | Q53QZ3 | 475 | RHG15_HUMAN Rho GTPase-activating protein 15 ... | 204 | 0.00002 | 52 | 24 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 14 | Q811M1 | 481 | RHG15_MOUSE Rho GTPase-activating protein 15 ... | 204 | 0.00006 | 50.1 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 15 | P46941 | 837 | TG325_CAEEL WW domain-containing protein tag-... | 154 | 0.00009 | 49.7 | 27 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 16 | A4IF90 | 471 | RHG15_BOVIN Rho GTPase-activating protein 15 ... | 204 | 0.0001 | 49.3 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 17 | Q2M1Z3 | 1444 | RHG31_HUMAN Rho GTPase-activating protein 31 ... | 104 | 0.0002 | 48.9 | 29 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 18 | P30337 | 334 | CHIN_RAT N-chimaerin OS=Rattus norvegicus (Ra... | 143 | 0.0002 | 47.8 | 29 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; TAS:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB. | 19 | Q91V57 | 459 | CHIN_MOUSE N-chimaerin OS=Mus musculus (Mouse... | 143 | 0.0002 | 48.1 | 29 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB. | 20 | Q17QN0 | 334 | CHIN_BOVIN N-chimaerin OS=Bos taurus (Bovine)... | 143 | 0.0003 | 47.4 | 29 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB. | 21 | O43586 | 416 | PPIP1_HUMAN Proline-serine-threonine phosphat... | 102 | 0.33 | 38.1 | 26 | 44 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome. | 22 | P15882 | 459 | CHIN_HUMAN N-chimaerin OS=Homo sapiens (Human... | 143 | 0.0005 | 47 | 29 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 23 | A6X8Z5 | 1425 | RHG31_MOUSE Rho GTPase-activating protein 31 ... | 104 | 0.001 | 46.2 | 28 | 49 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 24 | Q6PAJ1 | 1270 | BCR_MOUSE Breakpoint cluster region protein O... | 200 | 0.001 | 46.2 | 25 | 47 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0030675; F:Rac GTPase activator activity; IGI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 25 | A2AB59 | 869 | RHG27_MOUSE Rho GTPase-activating protein 27 ... | 200 | 0.002 | 45.8 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0006898; P:receptor-mediated endocytosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 26 | P11274 | 1271 | BCR_HUMAN Breakpoint cluster region protein O... | 200 | 0.002 | 45.8 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 27 | Q6PGG2 | 971 | GMIP_MOUSE GEM-interacting protein OS=Mus mus... | 145 | 0.002 | 45.4 | 26 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q12979 | 859 | ABR_HUMAN Active breakpoint cluster region-re... | 237 | 0.002 | 45.4 | 26 | 41 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 29 | Q6ZUM4 | 889 | RHG27_HUMAN Rho GTPase-activating protein 27 ... | 200 | 0.002 | 45.1 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro. | 30 | Q6TLK4 | 869 | RHG27_RAT Rho GTPase-activating protein 27 OS... | 200 | 0.003 | 45.1 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0017124; F:SH3 domain binding; IDA:HGNC. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:HGNC.::GO:0006898; P:receptor-mediated endocytosis; IMP:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro. | 31 | P97814 | 415 | PPIP1_MOUSE Proline-serine-threonine phosphat... | 109 | 0.25 | 38.1 | 26 | 44 | GO:0005826; C:actomyosin contractile ring; IDA:MGI.::GO:0032154; C:cleavage furrow; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IC:MGI. |