rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q9NYR8 | 311 | RDH8_HUMAN Retinol dehydrogenase 8 OS=Homo sa... | 134 | 0.00004 | 48.1 | 24 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; TAS:ProtInc. | 362 | O32229 | 264 | YVAG_BACSU Uncharacterized oxidoreductase yva... | 266 | 0.00004 | 47.8 | 21 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 363 | P40579 | 254 | YIV5_YEAST Uncharacterized oxidoreductase YIR... | 188 | 0.00004 | 47.8 | 24 | 49 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 364 | P0CR36 | 335 | TSC10_CRYNJ 3-ketodihydrosphingosine reductas... | 214 | 0.00004 | 48.1 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 365 | P0CR37 | 335 | TSC10_CRYNB 3-ketodihydrosphingosine reductas... | 214 | 0.00004 | 48.1 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 366 | Q9K151 | 261 | FABI_NEIMB Enoyl-[acyl-carrier-protein] reduc... | 160 | 0.00004 | 47.8 | 29 | 43 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 367 | P54616 | 258 | FABI_BACSU Enoyl-[acyl-carrier-protein] reduc... | 116 | 0.00004 | 47.8 | 31 | 49 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0070417; P:cellular response to cold; IEP:UniProtKB.::GO:0030497; P:fatty acid elongation; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.] | 368 | Q556J2 | 334 | KDSR_DICDI 3-ketodihydrosphingosine reductase... | 212 | 0.00004 | 47.8 | 25 | 43 | GO:0042406; C:extrinsic to endoplasmic reticulum membrane; ISS:dictyBase. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase. | 369 | Q49WS9 | 246 | Y1627_STAS1 Uncharacterized oxidoreductase SS... | 189 | 0.00005 | 47.4 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 370 | Q566S6 | 309 | DRS7B_DANRE Dehydrogenase/reductase SDR famil... | 196 | 0.00005 | 47.8 | 20 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 371 | Q2FZQ3 | 256 | FABI_STAA8 Enoyl-[acyl-carrier-protein] reduc... | 234 | 0.00006 | 47 | 25 | 44 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IDA:UniProtKB.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0050661; F:NADP binding; IDA:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 372 | Q9ZFE4 | 265 | FABI_PSEAE Enoyl-[acyl-carrier-protein] reduc... | 134 | 0.00007 | 47 | 31 | 48 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 373 | P51661 | 386 | DHI2_MOUSE Corticosteroid 11-beta-dehydrogena... | 151 | 0.00008 | 47.4 | 21 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 374 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 210 | 0.00009 | 47 | 25 | 40 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 375 | Q6CE86 | 372 | TSC10_YARLI 3-ketodihydrosphingosine reductas... | 203 | 0.0001 | 47 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 376 | P44432 | 262 | FABI_HAEIN Enoyl-[acyl-carrier-protein] reduc... | 113 | 0.0001 | 46.6 | 30 | 49 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 377 | O24990 | 275 | FABI_HELPY Enoyl-[acyl-carrier-protein] reduc... | 226 | 0.0001 | 46.6 | 29 | 46 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 378 | Q3T046 | 245 | BDH2_BOVIN 3-hydroxybutyrate dehydrogenase ty... | 145 | 0.0001 | 46.2 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 379 | Q9HBH5 | 336 | RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo ... | 263 | 0.0001 | 46.6 | 25 | 43 | GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 380 | Q3ZBV9 | 255 | DHR11_BOVIN Dehydrogenase/reductase SDR famil... | 258 | 0.0001 | 46.2 | 25 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 381 | P80365 | 405 | DHI2_HUMAN Corticosteroid 11-beta-dehydrogena... | 81 | 0.0001 | 46.6 | 27 | 48 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:ProtInc. | 382 | P66780 | 341 | Y1570_MYCBO Uncharacterized oxidoreductase Mb... | 177 | 0.0002 | 46.2 | 24 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 383 | P66779 | 341 | Y1543_MYCTU Uncharacterized oxidoreductase Rv... | 177 | 0.0002 | 46.2 | 24 | 45 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 384 | Q4L8Y1 | 231 | Y0585_STAHJ Uncharacterized oxidoreductase SH... | 234 | 0.0002 | 45.8 | 23 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 385 | P50233 | 400 | DHI2_RAT Corticosteroid 11-beta-dehydrogenase... | 142 | 0.0002 | 46.2 | 22 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0007565; P:female pregnancy; IEP:RGD.::GO:0008211; P:glucocorticoid metabolic process; IDA:RGD.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.] | 386 | Q8VCR2 | 304 | DHB13_MOUSE 17-beta-hydroxysteroid dehydrogen... | 217 | 0.0002 | 45.8 | 23 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 387 | Q6BQK1 | 328 | TSC10_DEBHA 3-ketodihydrosphingosine reductas... | 204 | 0.0002 | 45.8 | 20 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 388 | Q6PKH6 | 230 | DR4L2_HUMAN Dehydrogenase/reductase SDR famil... | 216 | 0.0002 | 45.1 | 25 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 389 | P80702 | 257 | DIDH_COMTE 3-alpha-hydroxysteroid dehydrogena... | 79 | 0.0003 | 45.1 | 37 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | | 390 | Q7SYS6 | 291 | DHI1B_XENLA Hydroxysteroid 11-beta-dehydrogen... | 212 | 0.0003 | 45.1 | 23 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 391 | Q05016 | 267 | YM71_YEAST Uncharacterized oxidoreductase YMR... | 215 | 0.0003 | 45.1 | 24 | 43 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:SGD. | | | | | | | | | | |