| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q6BXJ4 | 514 | JHD1_DEBHA JmjC domain-containing histone dem... | 517 | 1e-180 | 523 | 51 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q5A847 | 478 | JHD1_CANAL JmjC domain-containing histone dem... | 494 | 3e-161 | 473 | 50 | 66 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q6C423 | 510 | JHD1_YARLI JmjC domain-containing histone dem... | 407 | 1e-99 | 315 | 43 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q75AL5 | 486 | JHD1_ASHGO JmjC domain-containing histone dem... | 432 | 3e-86 | 280 | 38 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q6CIC9 | 478 | JHD1_KLULA JmjC domain-containing histone dem... | 431 | 2e-84 | 274 | 38 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | P40034 | 492 | JHD1_YEAST JmjC domain-containing histone dem... | 441 | 2e-81 | 267 | 37 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:SGD.::GO:0035064; F:methylated histone residue binding; IDA:SGD.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q4WHB7 | 1418 | JHD1_ASPFU JmjC domain-containing histone dem... | 457 | 6e-76 | 265 | 36 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q5AW75 | 1407 | JHD1_EMENI JmjC domain-containing histone dem... | 456 | 2e-75 | 263 | 36 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q6FPL6 | 403 | JHD1_CANGA JmjC domain-containing histone dem... | 339 | 2e-72 | 241 | 39 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q4P5U1 | 669 | JHD1_USTMA JmjC domain-containing histone dem... | 449 | 2e-68 | 237 | 35 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | P0CH95 | 1032 | PHF8_DANRE Histone lysine demethylase PHF8 OS... | 381 | 2e-62 | 224 | 34 | 50 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0071558; F:histone demethylase activity (H3-K27 specific); ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; ISS:UniProtKB.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q9UPP1 | 1060 | PHF8_HUMAN Histone lysine demethylase PHF8 OS... | 383 | 8e-60 | 216 | 34 | 50 | GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0071558; F:histone demethylase activity (H3-K27 specific); IDA:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); IDA:UniProtKB.::GO:0005506; F:iron ion binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IDA:UniProtKB.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q80TJ7 | 1023 | PHF8_MOUSE Histone lysine demethylase PHF8 OS... | 383 | 1e-59 | 216 | 33 | 52 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0071558; F:histone demethylase activity (H3-K27 specific); ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; ISS:UniProtKB.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q08D35 | 922 | KDM7_XENTR Lysine-specific demethylase 7 OS=X... | 408 | 2e-58 | 212 | 34 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0071558; F:histone demethylase activity (H3-K27 specific); ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | P0CF52 | 577 | KDM7B_DANRE Lysine-specific demethylase 7B OS... | 389 | 2e-58 | 207 | 34 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0071558; F:histone demethylase activity (H3-K27 specific); ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030901; P:midbrain development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q3UWM4 | 940 | KDM7_MOUSE Lysine-specific demethylase 7 OS=M... | 387 | 9e-58 | 209 | 35 | 50 | | | | | | | | | | | GO:0071558; F:histone demethylase activity (H3-K27 specific); IMP:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IMP:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q6ZMT4 | 941 | KDM7_HUMAN Lysine-specific demethylase 7 OS=H... | 387 | 4e-57 | 208 | 35 | 50 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0071558; F:histone demethylase activity (H3-K27 specific); IDA:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); IDA:UniProtKB.::GO:0005506; F:iron ion binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q9VHH9 | 1345 | JHD1_DROME JmjC domain-containing histone dem... | 273 | 2e-55 | 205 | 41 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IMP:FlyBase.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q9Y2K7 | 1162 | KDM2A_HUMAN Lysine-specific demethylase 2A OS... | 356 | 7e-55 | 203 | 35 | 52 | GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q5RHD1 | 875 | KDM7A_DANRE Lysine-specific demethylase 7A OS... | 381 | 2e-54 | 199 | 31 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0071558; F:histone demethylase activity (H3-K27 specific); ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0035575; F:histone demethylase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030901; P:midbrain development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q640I9 | 1259 | KDM2B_XENLA Lysine-specific demethylase 2B OS... | 300 | 4e-53 | 198 | 39 | 55 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | P59997 | 1161 | KDM2A_MOUSE Lysine-specific demethylase 2A OS... | 301 | 2e-52 | 196 | 37 | 53 | GO:0000790; C:nuclear chromatin; IDA:MGI.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0045322; F:unmethylated CpG binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q5U263 | 1146 | KDM2A_XENTR Lysine-specific demethylase 2A OS... | 290 | 8e-52 | 194 | 38 | 54 | GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q8NHM5 | 1336 | KDM2B_HUMAN Lysine-specific demethylase 2B OS... | 345 | 2e-51 | 193 | 36 | 53 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048596; P:embryonic camera-type eye morphogenesis; ISS:BHF-UCL.::GO:0021592; P:fourth ventricle development; ISS:BHF-UCL.::GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.::GO:0021993; P:initiation of neural tube closure; ISS:BHF-UCL.::GO:0021670; P:lateral ventricle development; ISS:BHF-UCL.::GO:0030901; P:midbrain development; ISS:BHF-UCL.::GO:0021555; P:midbrain-hindbrain boundary morphogenesis; ISS:BHF-UCL.::GO:2000178; P:negative regulation of neural precursor cell proliferation; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0007283; P:spermatogenesis; ISS:BHF-UCL.::GO:0021678; P:third ventricle development; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | Q6P1G2 | 1309 | KDM2B_MOUSE Lysine-specific demethylase 2B OS... | 274 | 9e-51 | 191 | 41 | 57 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048596; P:embryonic camera-type eye morphogenesis; IMP:BHF-UCL.::GO:0021592; P:fourth ventricle development; IMP:BHF-UCL.::GO:0021993; P:initiation of neural tube closure; IMP:BHF-UCL.::GO:0021670; P:lateral ventricle development; IMP:BHF-UCL.::GO:0030901; P:midbrain development; IMP:BHF-UCL.::GO:0021555; P:midbrain-hindbrain boundary morphogenesis; IMP:BHF-UCL.::GO:2000178; P:negative regulation of neural precursor cell proliferation; IMP:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0007283; P:spermatogenesis; IMP:BHF-UCL.::GO:0021678; P:third ventricle development; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | E6ZGB4 | 1081 | PHF2_DICLA Lysine-specific demethylase phf2 O... | 385 | 4e-49 | 186 | 31 | 47 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | O75151 | 1096 | PHF2_HUMAN Lysine-specific demethylase PHF2 O... | 387 | 7e-49 | 185 | 31 | 46 | GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0005506; F:iron ion binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0001889; P:liver development; TAS:UniProtKB.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q9WTU0 | 1096 | PHF2_MOUSE Lysine-specific demethylase PHF2 O... | 387 | 8e-49 | 185 | 31 | 47 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0061188; P:negative regulation of chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q6P949 | 1063 | PHF2_DANRE Lysine-specific demethylase phf2 O... | 383 | 2e-46 | 178 | 31 | 47 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0032454; F:histone demethylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0061188; P:negative regulation of chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | O94603 | 948 | JHD1_SCHPO Putative JmjC domain-containing hi... | 327 | 2e-45 | 174 | 32 | 49 | GO:0005720; C:nuclear heterochromatin; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006338; P:chromatin remodeling; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0090052; P:regulation of chromatin silencing at centromere; IMP:PomBase.::GO:0090054; P:regulation of chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0031454; P:regulation of extent of heterochromatin assembly; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | Q60V67 | 1063 | JHD1_CAEBR JmjC domain-containing histone dem... | 306 | 4e-44 | 171 | 36 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
