| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40530 | 394 | PDK_YEAST [Pyruvate dehydrogenase [lipoamide]... | 396 | 1e-52 | 186 | 34 | 51 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD. | 2 | O14874 | 412 | BCKD_HUMAN [3-methyl-2-oxobutanoate dehydroge... | 357 | 7e-33 | 132 | 29 | 47 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 3 | Q2KJG8 | 412 | BCKD_BOVIN [3-methyl-2-oxobutanoate dehydroge... | 357 | 8e-33 | 132 | 29 | 46 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 4 | Q00972 | 412 | BCKD_RAT [3-methyl-2-oxobutanoate dehydrogena... | 439 | 3e-32 | 130 | 27 | 45 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; IDA:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IMP:RGD.::GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; IDA:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 5 | O55028 | 412 | BCKD_MOUSE [3-methyl-2-oxobutanoate dehydroge... | 439 | 4e-32 | 130 | 27 | 45 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 6 | Q63065 | 434 | PDK1_RAT [Pyruvate dehydrogenase [lipoamide]]... | 333 | 1e-23 | 105 | 26 | 46 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IMP:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 7 | Q8BFP9 | 434 | PDK1_MOUSE [Pyruvate dehydrogenase [lipoamide... | 333 | 2e-22 | 102 | 26 | 46 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 8 | O70571 | 412 | PDK4_MOUSE [Pyruvate dehydrogenase [lipoamide... | 344 | 2e-22 | 101 | 26 | 44 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:MGI.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:MGI.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 9 | Q15119 | 407 | PDK2_HUMAN [Pyruvate dehydrogenase [lipoamide... | 341 | 3e-22 | 100 | 24 | 43 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 10 | Q1KMR4 | 412 | PDK4_RHIFE [Pyruvate dehydrogenase [lipoamide... | 391 | 5e-22 | 100 | 25 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 11 | O54937 | 412 | PDK4_RAT [Pyruvate dehydrogenase [lipoamide]]... | 344 | 6e-22 | 100 | 26 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 12 | Q9JK42 | 407 | PDK2_MOUSE [Pyruvate dehydrogenase [lipoamide... | 341 | 7e-22 | 100 | 23 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 13 | Q64536 | 407 | PDK2_RAT [Pyruvate dehydrogenase [lipoamide]]... | 341 | 8e-22 | 99.8 | 23 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 14 | Q15118 | 436 | PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide... | 342 | 1e-21 | 99.8 | 25 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 15 | O88345 | 412 | PDK4_SPETR [Pyruvate dehydrogenase [lipoamide... | 344 | 2e-20 | 96.3 | 26 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 16 | Q16654 | 411 | PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide... | 396 | 2e-20 | 95.5 | 25 | 43 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 17 | P91622 | 413 | PDK_DROME [Pyruvate dehydrogenase [lipoamide]... | 346 | 7e-19 | 91.7 | 27 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 18 | O02623 | 399 | PDK_ASCSU [Pyruvate dehydrogenase [lipoamide]... | 394 | 8e-18 | 88.2 | 24 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 19 | Q922H2 | 415 | PDK3_MOUSE [Pyruvate dehydrogenase [lipoamide... | 342 | 1e-16 | 84.7 | 25 | 41 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 20 | Q15120 | 406 | PDK3_HUMAN [Pyruvate dehydrogenase [lipoamide... | 342 | 2e-16 | 84.7 | 26 | 41 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 21 | Q02332 | 401 | PDHK2_CAEEL Probable [pyruvate dehydrogenase ... | 398 | 6e-16 | 82.8 | 24 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 22 | P53170 | 491 | PKP2_YEAST Pyruvate dehydrogenase kinase 2, m... | 305 | 0.00000000000001 | 79.3 | 27 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD. | 23 | Q9P6P9 | 425 | PDK_SCHPO [Pyruvate dehydrogenase [lipoamide]... | 246 | 0.0000000000006 | 73.6 | 28 | 45 | GO:0005967; C:mitochondrial pyruvate dehydrogenase complex; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; ISS:PomBase.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; ISS:PomBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 24 | Q9RDT3 | 415 | WALK_STAAU Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 45.1 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 25 | A6QD58 | 608 | WALK_STAAE Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 26 | Q7A215 | 608 | WALK_STAAW Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 27 | A8YYU2 | 608 | WALK_STAAT Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 28 | Q6GD71 | 608 | WALK_STAAS Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 29 | Q7A8E0 | 608 | WALK_STAAN Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 30 | Q7A305 | 608 | WALK_STAAM Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 31 | Q5HJX6 | 608 | WALK_STAAC Sensor protein kinase walK OS=Stap... | 191 | 0.001 | 44.7 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. |
