rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q5RD06 | 451 | POC1B_PONAB POC1 centriolar protein homolog B... | 118 | 0.082 | 39.3 | 26 | 46 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB. | 32 | Q8TC44 | 478 | POC1B_HUMAN POC1 centriolar protein homolog B... | 118 | 0.076 | 39.7 | 26 | 46 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0042384; P:cilium assembly; IMP:UniProtKB. | 33 | Q8N136 | 415 | WDR69_HUMAN Outer row dynein assembly protein... | 213 | 0.0005 | 46.2 | 23 | 42 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 34 | Q58D20 | 485 | NLE1_BOVIN Notchless protein homolog 1 OS=Bos... | 414 | 0.001 | 45.4 | 21 | 34 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 35 | Q9NVX2 | 485 | NLE1_HUMAN Notchless protein homolog 1 OS=Hom... | 227 | 0.00003 | 50.1 | 23 | 39 | GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 36 | O14727 | 1248 | APAF_HUMAN Apoptotic protease-activating fact... | 75 | 7.6 | 33.5 | 27 | 43 | GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc. | 37 | Q5RFF8 | 485 | NLE1_PONAB Notchless protein homolog 1 OS=Pon... | 414 | 0.00004 | 50.1 | 21 | 35 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 38 | Q8I0F4 | 419 | LIS1_DICDI Lissencephaly-1 homolog OS=Dictyos... | 238 | 0.000004 | 52.8 | 25 | 40 | GO:0031592; C:centrosomal corona; IDA:dictyBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0045504; F:dynein heavy chain binding; IPI:dictyBase.::GO:0017048; F:Rho GTPase binding; IPI:dictyBase. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051642; P:centrosome localization; IMP:dictyBase.::GO:0051645; P:Golgi localization; IMP:dictyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 39 | Q9V3J8 | 361 | WDS_DROME Protein will die slowly OS=Drosophi... | 120 | 0.005 | 43.1 | 30 | 47 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase. | 40 | P97499 | 2629 | TEP1_MOUSE Telomerase protein component 1 OS=... | 312 | 1.8 | 35.4 | 21 | 39 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IMP:UniProtKB. | | | | | | | | | | | 41 | Q86VZ2 | 330 | WDR5B_HUMAN WD repeat-containing protein 5B O... | 113 | 0.006 | 42.7 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 42 | Q4R8E7 | 415 | WDR69_MACFA Outer row dynein assembly protein... | 322 | 0.00002 | 51.2 | 22 | 39 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 43 | P25382 | 515 | NLE1_YEAST Ribosome assembly protein 4 OS=Sac... | 132 | 1.1 | 35.8 | 24 | 40 | GO:0005730; C:nucleolus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000027; P:ribosomal large subunit assembly; IMP:SGD. | 44 | Q9FLX9 | 473 | NLE1_ARATH Notchless protein homolog OS=Arabi... | 121 | 6.4 | 33.5 | 22 | 39 | GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 45 | Q17963 | 376 | TG125_CAEEL WD repeat-containing protein tag-... | 113 | 0.032 | 40.4 | 25 | 45 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 46 | Q8W1K8 | 370 | MUT11_CHLRE Protein Mut11 OS=Chlamydomonas re... | 112 | 0.98 | 35.8 | 24 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 47 | Q5RE95 | 330 | WDR5B_PONAB WD repeat-containing protein 5B O... | 113 | 0.004 | 43.1 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 48 | P38011 | 319 | GBLP_YEAST Guanine nucleotide-binding protein... | 81 | 4.9 | 33.5 | 30 | 44 | GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD. | | | | | | | | | | GO:0001965; F:G-protein alpha-subunit binding; IPI:SGD.::GO:0005092; F:GDP-dissociation inhibitor activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IMP:SGD. | | | | | | | | | | GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:SGD.::GO:0010255; P:glucose mediated signaling pathway; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD. | 49 | Q00659 | 678 | SCONB_EMENI Probable E3 ubiquitin ligase comp... | 61 | 4.8 | 33.9 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 50 | Q498M4 | 334 | WDR5_RAT WD repeat-containing protein 5 OS=Ra... | 116 | 0.006 | 42.7 | 31 | 45 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 116 | 0.006 | 42.7 | 31 | 45 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 116 | 0.006 | 42.7 | 31 | 45 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 53 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 116 | 0.007 | 42.7 | 31 | 45 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 54 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 116 | 0.006 | 42.7 | 31 | 45 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | Q9USN3 | 777 | UTP13_SCHPO Probable U3 small nucleolar RNA-a... | 77 | 1.4 | 35.4 | 23 | 52 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.::GO:0032040; C:small-subunit processome; IEA:InterPro. | | | | | | | | | | GO:0030515; F:snoRNA binding; ISS:PomBase. | | | | | | | | | | GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase. | 56 | Q8VBV4 | 629 | FBXW7_MOUSE F-box/WD repeat-containing protei... | 199 | 2.8 | 34.7 | 20 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 57 | O08653 | 2629 | TEP1_RAT Telomerase protein component 1 OS=Ra... | 352 | 0.007 | 43.1 | 19 | 37 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 58 | O74855 | 502 | NLE1_SCHPO Ribosome assembly protein C18.05c ... | 188 | 0.014 | 42 | 24 | 39 | GO:0005730; C:nucleolus; ISS:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0042254; P:ribosome biogenesis; ISS:PomBase. | 59 | Q9D7H2 | 328 | WDR5B_MOUSE WD repeat-containing protein 5B O... | 118 | 0.025 | 40.8 | 28 | 48 | | | | | | | | | | | | | | | | | | | | | | 60 | Q969H0 | 707 | FBXW7_HUMAN F-box/WD repeat-containing protei... | 199 | 5.3 | 33.9 | 20 | 42 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL. | 61 | Q23256 | 501 | YH92_CAEEL Uncharacterized WD repeat-containi... | 218 | 0.0000003 | 57 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | |