rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | Q3ULA2 | 605 | FBW1A_MOUSE F-box/WD repeat-containing protei... | 151 | 0.29 | 37.4 | 24 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 452 | P49178 | 380 | GBB_MAIZE Guanine nucleotide-binding protein ... | 175 | 0.29 | 37.4 | 27 | 45 | | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 453 | B3RNR8 | 313 | CIAO1_TRIAD Probable cytosolic iron-sulfur pr... | 39 | 0.29 | 37 | 33 | 56 | | | | | | | | | | | | | | | | | | | | | GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB. | 454 | Q9DCE5 | 382 | PK1IP_MOUSE p21-activated protein kinase-inte... | 124 | 0.3 | 37.4 | 27 | 44 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW. | 455 | Q05B17 | 678 | WDR48_XENTR WD repeat-containing protein 48 O... | 196 | 0.3 | 37.4 | 20 | 44 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0016579; P:protein deubiquitination; ISS:UniProtKB. | 456 | Q8I0F4 | 419 | LIS1_DICDI Lissencephaly-1 homolog OS=Dictyos... | 72 | 0.3 | 37.4 | 29 | 56 | GO:0031592; C:centrosomal corona; IDA:dictyBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0045504; F:dynein heavy chain binding; IPI:dictyBase.::GO:0017048; F:Rho GTPase binding; IPI:dictyBase. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051642; P:centrosome localization; IMP:dictyBase.::GO:0051645; P:Golgi localization; IMP:dictyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 457 | Q921E6 | 441 | EED_MOUSE Polycomb protein EED OS=Mus musculu... | 140 | 0.3 | 37.4 | 24 | 42 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0001739; C:sex chromatin; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI. | | | | | | | | | | GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 458 | O75530 | 441 | EED_HUMAN Polycomb protein EED OS=Homo sapien... | 140 | 0.3 | 37.4 | 24 | 42 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0042054; F:histone methyltransferase activity; IDA:MGI.::GO:0042802; F:identical protein binding; IPI:IntAct. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 459 | Q3SZ25 | 441 | EED_BOVIN Polycomb protein EED OS=Bos taurus ... | 140 | 0.31 | 37.4 | 24 | 42 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 460 | Q6BRG6 | 811 | ERB1_DEBHA Ribosome biogenesis protein ERB1 O... | 124 | 0.31 | 37.4 | 28 | 44 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. | 461 | Q9Y297 | 605 | FBW1A_HUMAN F-box/WD repeat-containing protei... | 151 | 0.31 | 37.4 | 24 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 462 | O22607 | 507 | MSI4_ARATH WD-40 repeat-containing protein MS... | 72 | 0.31 | 37.4 | 28 | 53 | GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR. | | | | | | | | | | GO:0046872; F:metal ion binding; IDA:TAIR. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010224; P:response to UV-B; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 463 | Q6FQU2 | 534 | YD156_CANGA WD repeat-containing protein CAGL... | 80 | 0.32 | 37.4 | 33 | 49 | | | | | | | | | | | | | | | | | | | | | | 464 | Q1E6Q0 | 525 | YD156_COCIM WD repeat-containing protein CIMG... | 121 | 0.32 | 37.4 | 21 | 40 | | | | | | | | | | | | | | | | | | | | | | 465 | Q91854 | 518 | TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric... | 151 | 0.33 | 37.4 | 24 | 44 | | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 466 | B9WN49 | 1098 | RTC1_CANDC Restriction of telomere capping pr... | 41 | 0.33 | 37.4 | 39 | 66 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 467 | O22466 | 424 | MSI1_SOLLC WD-40 repeat-containing protein MS... | 110 | 0.34 | 37 | 25 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 468 | O35353 | 340 | GBB4_RAT Guanine nucleotide-binding protein s... | 267 | 0.34 | 37 | 23 | 37 | | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 469 | Q969H0 | 707 | FBXW7_HUMAN F-box/WD repeat-containing protei... | 150 | 0.62 | 36.6 | 22 | 45 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL. | 470 | Q55563 | 1693 | Y163_SYNY3 Uncharacterized WD repeat-containi... | 135 | 0.35 | 37.4 | 27 | 45 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 471 | P91343 | 439 | WDR12_CAEEL Ribosome biogenesis protein WDR12... | 97 | 0.36 | 37 | 27 | 46 | GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007276; P:gamete generation; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040019; P:positive regulation of embryonic development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase. | 472 | Q01277 | 650 | SCONB_NEUCR Probable E3 ubiquitin ligase comp... | 165 | 0.36 | 37.4 | 22 | 45 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 473 | P33215 | 660 | NEDD1_MOUSE Protein NEDD1 OS=Mus musculus (Mo... | 207 | 0.36 | 37.4 | 21 | 42 | GO:0045177; C:apical part of cell; IDA:MGI.::GO:0005814; C:centriole; IDA:MGI.::GO:0005932; C:microtubule basal body; IDA:MGI.::GO:0000242; C:pericentriolar material; IDA:MGI.::GO:0000922; C:spindle pole; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 474 | Q4V837 | 710 | DTLA_XENLA Denticleless protein homolog A OS=... | 118 | 0.37 | 37.4 | 30 | 50 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 475 | Q99973 | 2627 | TEP1_HUMAN Telomerase protein component 1 OS=... | 106 | 0.38 | 37.4 | 28 | 46 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016363; C:nuclear matrix; IDA:MGI.::GO:0005625; C:soluble fraction; ISS:UniProtKB.::GO:0005697; C:telomerase holoenzyme complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0000722; P:telomere maintenance via recombination; IDA:UniProtKB. | 476 | A6PWY4 | 622 | WDR76_MOUSE WD repeat-containing protein 76 O... | 179 | 6.7 | 33.1 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | | 477 | O75083 | 606 | WDR1_HUMAN WD repeat-containing protein 1 OS=... | 159 | 0.39 | 37 | 26 | 44 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0007605; P:sensory perception of sound; TAS:ProtInc. | 478 | Q0UNA9 | 302 | SEC13_PHANO Protein transport protein SEC13 O... | 156 | 0.41 | 36.6 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 479 | Q24338 | 425 | ESC_DROME Polycomb protein esc OS=Drosophila ... | 134 | 0.41 | 37 | 24 | 43 | GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0000790; C:nuclear chromatin; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct. | | | | | | | | | | GO:0006342; P:chromatin silencing; IPI:FlyBase.::GO:0048096; P:chromatin-mediated maintenance of transcription; NAS:UniProtKB.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0070734; P:histone H3-K27 methylation; IMP:FlyBase.::GO:0051567; P:histone H3-K9 methylation; IC:GOC.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 480 | Q54DM1 | 331 | BUB3_DICDI Mitotic checkpoint protein bub3 OS... | 114 | 0.43 | 36.6 | 25 | 45 | GO:0000776; C:kinetochore; ISS:dictyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:dictyBase. | 481 | Q6CMA2 | 333 | CIAO1_KLULA Probable cytosolic iron-sulfur pr... | 108 | 0.46 | 36.6 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | |