rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q2KIJ5 | 331 | KDSR_BOVIN 3-ketodihydrosphingosine reductase... | 180 | 0.45 | 35.4 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 182 | P16152 | 277 | CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Ho... | 149 | 0.46 | 35 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:UniProtKB.::GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB. | 183 | Q8CHS7 | 311 | DRS7C_MOUSE Dehydrogenase/reductase SDR famil... | 156 | 0.46 | 35 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 184 | Q9ASX2 | 266 | TRNH1_ARATH Tropinone reductase homolog At1g0... | 198 | 0.46 | 35 | 23 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0080167; P:response to karrikin; IEP:TAIR. | 185 | P40398 | 299 | YHXD_BACSU Uncharacterized oxidoreductase yhx... | 198 | 0.52 | 35 | 24 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 186 | A6NNS2 | 312 | DRS7C_HUMAN Dehydrogenase/reductase SDR famil... | 120 | 0.53 | 35 | 28 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 187 | O77769 | 302 | DHRS3_BOVIN Short-chain dehydrogenase/reducta... | 209 | 0.54 | 35 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 188 | Q9ZUH5 | 296 | SDR2_ARATH Short-chain dehydrogenase/reductas... | 165 | 0.55 | 35 | 24 | 41 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 189 | O13908 | 261 | YF3H_SCHPO Uncharacterized oxidoreductase C22... | 181 | 0.6 | 34.7 | 22 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 190 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 86 | 0.61 | 35 | 26 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 191 | P15428 | 266 | PGDH_HUMAN 15-hydroxyprostaglandin dehydrogen... | 239 | 0.68 | 34.7 | 21 | 39 | GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IDA:UniProtKB.::GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 192 | A4UHT7 | 311 | SALR_PAPBR Salutaridine reductase OS=Papaver ... | 274 | 0.7 | 34.7 | 21 | 35 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047037; F:salutaridine reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW. | 193 | Q5RA68 | 418 | HSDL2_PONAB Hydroxysteroid dehydrogenase-like... | 235 | 0.72 | 34.7 | 20 | 38 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 194 | O75911 | 302 | DHRS3_HUMAN Short-chain dehydrogenase/reducta... | 213 | 0.78 | 34.3 | 23 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; TAS:ProtInc.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042572; P:retinol metabolic process; TAS:UniProtKB.::GO:0007601; P:visual perception; TAS:ProtInc. | 195 | Q8MJY8 | 266 | PGDH_MACFA 15-hydroxyprostaglandin dehydrogen... | 239 | 0.8 | 34.3 | 21 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; IEP:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 196 | P51976 | 406 | DHI2_RABIT Corticosteroid 11-beta-dehydrogena... | 203 | 0.8 | 34.7 | 24 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 197 | Q05A13 | 316 | S16C6_MOUSE Short-chain dehydrogenase/reducta... | 204 | 0.87 | 34.3 | 23 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 198 | Q71R50 | 255 | DHR11_CHICK Dehydrogenase/reductase SDR famil... | 224 | 0.88 | 34.3 | 23 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 199 | Q8W3D9 | 402 | PORB_ORYSJ Protochlorophyllide reductase B, c... | 97 | 0.9 | 34.3 | 27 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 200 | P39644 | 259 | YWFH_BACSU Bacilysin biosynthesis oxidoreduct... | 207 | 0.93 | 34.3 | 22 | 38 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 201 | P16542 | 272 | DHK1_STRVN Granaticin polyketide synthase put... | 214 | 0.93 | 34.3 | 21 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 202 | Q12452 | 347 | ERG27_YEAST 3-keto-steroid reductase OS=Sacch... | 236 | 0.96 | 34.3 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IMP:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 203 | Q28960 | 289 | CBR1_PIG Carbonyl reductase [NADPH] 1 OS=Sus ... | 99 | 1 | 33.9 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 204 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 206 | 1 | 34.3 | 20 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 205 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 179 | 1.1 | 34.3 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 206 | Q7Z4W1 | 244 | DCXR_HUMAN L-xylulose reductase OS=Homo sapie... | 177 | 1.1 | 33.9 | 27 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 207 | O34782 | 263 | YVRD_BACSU Uncharacterized oxidoreductase yvr... | 197 | 1.1 | 33.9 | 22 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 208 | Q51576 | 255 | Y3106_PSEAE Uncharacterized oxidoreductase PA... | 149 | 1.1 | 33.9 | 26 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 209 | Q8MI29 | 277 | CBR1_MACFA Carbonyl reductase [NADPH] 1 OS=Ma... | 149 | 1.1 | 33.9 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 210 | Q29608 | 291 | DHI1_SAISC Corticosteroid 11-beta-dehydrogena... | 175 | 1.1 | 33.9 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 211 | O31680 | 248 | YKVO_BACSU Uncharacterized oxidoreductase ykv... | 174 | 1.2 | 33.9 | 23 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |