rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | P25963 | 317 | IKBA_HUMAN NF-kappa-B inhibitor alpha OS=Homo... | 172 | 0.00005 | 50.4 | 30 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0008139; F:nuclear localization sequence binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0070417; P:cellular response to cold; NAS:BHF-UCL.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:BHF-UCL.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043392; P:negative regulation of DNA binding; NAS:UniProtKB.::GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.::GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.::GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 542 | Q07008 | 2531 | NOTC1_RAT Neurogenic locus notch homolog prot... | 126 | 0.15 | 40 | 28 | 51 | GO:0001669; C:acrosomal vesicle; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048708; P:astrocyte differentiation; IDA:RGD.::GO:0021515; P:cell differentiation in spinal cord; IEP:RGD.::GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; ISS:UniProtKB.::GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.::GO:2000974; P:negative regulation of pro-B cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0045603; P:positive regulation of endothelial cell differentiation; IMP:RGD.::GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:RGD.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; ISS:UniProtKB.::GO:0007221; P:positive regulation of transcription of Notch receptor target; IMP:RGD.::GO:0031960; P:response to corticosteroid stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0007283; P:spermatogenesis; IMP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 543 | Q9J5I9 | 331 | V012_FOWPN Putative ankyrin repeat protein FP... | 148 | 0.098 | 40 | 27 | 47 | | | | | | | | | | | | | | | | | | | | | | 544 | Q2T9W8 | 424 | ANR61_BOVIN Ankyrin repeat domain-containing ... | 199 | 0.0000001 | 59.3 | 27 | 46 | | | | | | | | | | | | | | | | | | | | | | 545 | Q9BZF9 | 1416 | UACA_HUMAN Uveal autoantigen with coiled-coil... | 168 | 0.000002 | 55.8 | 28 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 546 | Q01705 | 2531 | NOTC1_MOUSE Neurogenic locus notch homolog pr... | 126 | 0.15 | 40 | 28 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0072044; P:collecting duct development; IEP:UniProtKB.::GO:0072017; P:distal tubule development; IEP:UniProtKB.::GO:0003160; P:endocardium morphogenesis; IEP:BHF-UCL.::GO:0072144; P:glomerular mesangial cell development; IEP:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0060253; P:negative regulation of glial cell proliferation; IDA:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; IDA:UniProtKB.::GO:0048715; P:negative regulation of oligodendrocyte differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.::GO:2000974; P:negative regulation of pro-B cell differentiation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; IC:UniProtKB.::GO:0002051; P:osteoblast fate commitment; NAS:BHF-UCL.::GO:0048711; P:positive regulation of astrocyte differentiation; IDA:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:UniProtKB.::GO:0032495; P:response to muramyl dipeptide; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 547 | Q5JPF3 | 1778 | AN36C_HUMAN Ankyrin repeat domain-containing ... | 112 | 0.002 | 46.6 | 29 | 47 | | | | | | | | | | | GO:0008200; F:ion channel inhibitor activity; NAS:UniProtKB. | | | | | | | | | | | 548 | Q5UQX8 | 255 | YR880_MIMIV Putative ankyrin repeat protein R... | 191 | 0.71 | 37 | 24 | 47 | | | | | | | | | | | | | | | | | | | | | | 549 | Q4UKJ3 | 124 | Y1087_RICFE Putative ankyrin repeat protein R... | 90 | 0.02 | 40 | 33 | 49 | | | | | | | | | | | | | | | | | | | | | | 550 | Q9J503 | 482 | V232_FOWPN Putative ankyrin repeat protein FP... | 268 | 0.011 | 43.5 | 24 | 43 | | | | | | | | | | | | | | | | | | | | | | 551 | Q9GL21 | 1415 | UACA_CANFA Uveal autoantigen with coiled-coil... | 181 | 0.000002 | 55.8 | 28 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 552 | Q3SX00 | 228 | ANR46_BOVIN Ankyrin repeat domain-containing ... | 69 | 0.072 | 40 | 35 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 553 | Q9J505 | 188 | V230_FOWPN Putative ankyrin repeat protein FP... | 72 | 1.6 | 35.4 | 26 | 51 | | | | | | | | | | | | | | | | | | | | | | 554 | Q5R8C8 | 228 | ANR46_PONAB Ankyrin repeat domain-containing ... | 69 | 0.072 | 40 | 35 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 555 | Q499M5 | 370 | ANR16_RAT Ankyrin repeat domain-containing pr... | 336 | 0.0000002 | 58.2 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | | 556 | Q9SQK3 | 315 | EM506_ARATH Ankyrin repeat domain-containing ... | 101 | 0.064 | 40.4 | 33 | 46 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 557 | Q86W74 | 232 | ANR46_HUMAN Ankyrin repeat domain-containing ... | 69 | 0.053 | 40.4 | 35 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 558 | Q9Y566 | 2161 | SHAN1_HUMAN SH3 and multiple ankyrin repeat d... | 99 | 0.029 | 42.4 | 32 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; ISS:BHF-UCL.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0071532; F:ankyrin repeat binding; ISS:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL. | | | | | | | | | | GO:0008306; P:associative learning; ISS:BHF-UCL.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0007616; P:long-term memory; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL. | 559 | Q3TYA6 | 858 | MPP8_MOUSE M-phase phosphoprotein 8 OS=Mus mu... | 129 | 0.0004 | 48.1 | 28 | 47 | GO:0005720; C:nuclear heterochromatin; ISS:UniProtKB.::GO:0000788; C:nuclear nucleosome; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0044030; P:regulation of DNA methylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 560 | Q9Z1P7 | 791 | KANK3_MOUSE KN motif and ankyrin repeat domai... | 111 | 0.007 | 44.3 | 31 | 52 | | | | | | | | | | | | | | | | | | | | | | 561 | P53356 | 757 | HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=... | 145 | 0.049 | 41.6 | 28 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 562 | Q5UQF2 | 109 | YL482_MIMIV Putative ankyrin repeat protein L... | 114 | 0.042 | 38.9 | 25 | 48 | | | | | | | | | | | | | | | | | | | | | | 563 | Q5UPG7 | 642 | YL091_MIMIV Putative ankyrin repeat protein L... | 101 | 0.011 | 43.5 | 30 | 51 | | | | | | | | | | | | | | | | | | | | | | 564 | G3V8T1 | 851 | MPP8_RAT M-phase phosphoprotein 8 OS=Rattus n... | 133 | 0.008 | 43.9 | 32 | 49 | GO:0005720; C:nuclear heterochromatin; ISS:UniProtKB.::GO:0000788; C:nuclear nucleosome; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0044030; P:regulation of DNA methylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 565 | Q6FJ70 | 763 | AKR1_CANGA Palmitoyltransferase AKR1 OS=NRRL ... | 75 | 0.2 | 39.7 | 35 | 47 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 566 | Q6GQW0 | 1109 | BTBDB_MOUSE Ankyrin repeat and BTB/POZ domain... | 92 | 0.18 | 39.7 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | | 567 | Q9Z1E3 | 314 | IKBA_MOUSE NF-kappa-B inhibitor alpha OS=Mus ... | 121 | 0.008 | 43.5 | 29 | 41 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:MGI.::GO:0070427; P:nucleotide-binding oligomerization domain containing 1 signaling pathway; IDA:MGI.::GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:MGI.::GO:0000060; P:protein import into nucleus, translocation; IDA:MGI.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0032495; P:response to muramyl dipeptide; IDA:MGI.::GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:MGI. | 568 | Q54XX5 | 848 | Y9849_DICDI Probable serine/threonine-protein... | 178 | 0.022 | 42.7 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 569 | A6QL63 | 1104 | BTBDB_HUMAN Ankyrin repeat and BTB/POZ domain... | 92 | 0.22 | 39.7 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | | 570 | P55273 | 166 | CDN2D_HUMAN Cyclin-dependent kinase 4 inhibit... | 62 | 0.0003 | 46.2 | 39 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0048102; P:autophagic cell death; IMP:BHF-UCL.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0032526; P:response to retinoic acid; IMP:BHF-UCL.::GO:0009411; P:response to UV; IMP:BHF-UCL.::GO:0033280; P:response to vitamin D; IMP:BHF-UCL. | 571 | Q99549 | 860 | MPP8_HUMAN M-phase phosphoprotein 8 OS=Homo s... | 125 | 0.026 | 42.4 | 31 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005720; C:nuclear heterochromatin; IDA:UniProtKB.::GO:0000788; C:nuclear nucleosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0044030; P:regulation of DNA methylation; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |