| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | B4JSC2 | 630 | FOXO_DROGR Forkhead box protein O OS=Drosophi... | 55 | 0.0005 | 47.8 | 40 | 56 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 92 | Q5W1J5 | 578 | FOXP1_XENLA Forkhead box protein P1 OS=Xenopu... | 84 | 0.0005 | 47.4 | 30 | 50 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 93 | Q99JB6 | 429 | FOXP3_MOUSE Forkhead box protein P3 OS=Mus mu... | 51 | 0.0005 | 47.4 | 41 | 61 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0035035; F:histone acetyltransferase binding; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0051525; F:NFAT protein binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001782; P:B cell homeostasis; IMP:MGI.::GO:0002361; P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IMP:MGI.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0001816; P:cytokine production; IDA:MGI.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0002262; P:myeloid cell homeostasis; IMP:MGI.::GO:0002677; P:negative regulation of chronic inflammatory response; IDA:MGI.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.::GO:0035067; P:negative regulation of histone acetylation; IDA:MGI.::GO:0031064; P:negative regulation of histone deacetylation; IBA:RefGenome.::GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IDA:MGI.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; ISS:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; ISS:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; ISS:UniProtKB.::GO:0032714; P:negative regulation of interleukin-5 production; IDA:MGI.::GO:0032715; P:negative regulation of interleukin-6 production; IMP:MGI.::GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IMP:MGI.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; ISS:UniProtKB.::GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IMP:MGI.::GO:0035066; P:positive regulation of histone acetylation; IDA:MGI.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:MGI.::GO:0002851; P:positive regulation of peripheral T cell tolerance induction; IMP:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032914; P:positive regulation of transforming growth factor beta1 production; IDA:MGI.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0048302; P:regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0002456; P:T cell mediated immunity; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI.::GO:0002513; P:tolerance induction to self antigen; IMP:MGI. | 94 | Q9PVY9 | 465 | FXC2A_XENLA Forkhead box protein C2-A OS=Xeno... | 51 | 0.0005 | 47.4 | 39 | 63 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0007498; P:mesoderm development; IEP:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 95 | P0CF24 | 710 | FOXP2_RAT Forkhead box protein P2 OS=Rattus n... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; IBA:RefGenome.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome. | 96 | B4MB78 | 609 | FOXO_DROVI Forkhead box protein O OS=Drosophi... | 61 | 0.0005 | 47.4 | 39 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 97 | P58463 | 714 | FOXP2_MOUSE Forkhead box protein P2 OS=Mus mu... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IGI:MGI.::GO:0040007; P:growth; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IGI:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IMP:MGI.::GO:0007519; P:skeletal muscle tissue development; IGI:MGI.::GO:0048745; P:smooth muscle tissue development; IGI:MGI.::GO:0042297; P:vocal learning; IMP:MGI. | 98 | Q61572 | 553 | FOXC1_MOUSE Forkhead box protein C1 OS=Mus mu... | 51 | 0.0005 | 47.4 | 39 | 63 | GO:0005720; C:nuclear heterochromatin; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; ISS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IGI:MGI.::GO:0048844; P:artery morphogenesis; IMP:MGI.::GO:0001974; P:blood vessel remodeling; IGI:MGI.::GO:0007420; P:brain development; IMP:MGI.::GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0060038; P:cardiac muscle cell proliferation; IGI:MGI.::GO:0030199; P:collagen fibril organization; IMP:MGI.::GO:0035050; P:embryonic heart tube development; IGI:MGI.::GO:0008354; P:germ cell migration; IMP:MGI.::GO:0030203; P:glycosaminoglycan metabolic process; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0032808; P:lacrimal gland development; IMP:MGI.::GO:0001946; P:lymphangiogenesis; IBA:RefGenome.::GO:0001656; P:metanephros development; IBA:RefGenome.::GO:0045930; P:negative regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0014032; P:neural crest cell development; IGI:MGI.::GO:0014034; P:neural crest cell fate commitment; IBA:RefGenome.::GO:0007219; P:Notch signaling pathway; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.::GO:0001503; P:ossification; IMP:MGI.::GO:0001541; P:ovarian follicle development; IMP:MGI.::GO:0048343; P:paraxial mesodermal cell fate commitment; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0050880; P:regulation of blood vessel size; IGI:MGI.::GO:0046620; P:regulation of organ growth; IGI:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0001756; P:somitogenesis; IGI:UniProtKB.::GO:0001657; P:ureteric bud development; IMP:MGI.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IGI:MGI.::GO:0001570; P:vasculogenesis; IBA:RefGenome.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IGI:MGI. | 99 | Q5QL03 | 713 | FOXP2_HYLLA Forkhead box protein P2 OS=Hyloba... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 100 | Q8MJ99 | 713 | FOXP2_GORGO Forkhead box protein P2 OS=Gorill... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 101 | Q8MJ97 | 714 | FOXP2_MACMU Forkhead box protein P2 OS=Macaca... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome. | 102 | O15409 | 715 | FOXP2_HUMAN Forkhead box protein P2 OS=Homo s... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; IMP:UniProtKB.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IEP:BHF-UCL.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; IMP:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome. | 103 | Q8MJA0 | 716 | FOXP2_PANTR Forkhead box protein P2 OS=Pan tr... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0021987; P:cerebral cortex development; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040007; P:growth; IBA:RefGenome.::GO:0048286; P:lung alveolus development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060013; P:righting reflex; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0042297; P:vocal learning; IBA:RefGenome. | 104 | Q8HZ00 | 716 | FOXP2_PANPA Forkhead box protein P2 OS=Pan pa... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 105 | Q8MJ98 | 713 | FOXP2_PONPY Forkhead box protein P2 OS=Pongo ... | 50 | 0.0005 | 47.4 | 38 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 106 | Q6NVT7 | 464 | FOXC2_XENTR Forkhead box protein C2 OS=Xenopu... | 51 | 0.0006 | 47 | 39 | 63 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IBA:RefGenome.::GO:0048844; P:artery morphogenesis; IBA:RefGenome.::GO:0001974; P:blood vessel remodeling; IBA:RefGenome.::GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0060038; P:cardiac muscle cell proliferation; IBA:RefGenome.::GO:0030199; P:collagen fibril organization; IBA:RefGenome.::GO:0035050; P:embryonic heart tube development; IBA:RefGenome.::GO:0048703; P:embryonic viscerocranium morphogenesis; IBA:RefGenome.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0001946; P:lymphangiogenesis; ISS:UniProtKB.::GO:0001656; P:metanephros development; IBA:RefGenome.::GO:0014034; P:neural crest cell fate commitment; IBA:RefGenome.::GO:0007219; P:Notch signaling pathway; IBA:RefGenome.::GO:0001503; P:ossification; IBA:RefGenome.::GO:0048343; P:paraxial mesodermal cell fate commitment; IBA:RefGenome.::GO:0001569; P:patterning of blood vessels; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0050880; P:regulation of blood vessel size; IBA:RefGenome.::GO:0046620; P:regulation of organ growth; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0001756; P:somitogenesis; IBA:RefGenome.::GO:0001657; P:ureteric bud development; IBA:RefGenome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IBA:RefGenome.::GO:0001570; P:vasculogenesis; IBA:RefGenome.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IBA:RefGenome. | 107 | Q9PVY8 | 461 | FXC2B_XENLA Forkhead box protein C2-B OS=Xeno... | 51 | 0.0006 | 47 | 39 | 63 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 108 | Q33BP8 | 485 | FOXN3_PIG Forkhead box protein N3 OS=Sus scro... | 55 | 0.0007 | 47 | 31 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 109 | O00409 | 490 | FOXN3_HUMAN Forkhead box protein N3 OS=Homo s... | 55 | 0.0007 | 47 | 31 | 60 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; TAS:ProtInc.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000085; P:G2 phase of mitotic cell cycle; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 110 | Q12948 | 553 | FOXC1_HUMAN Forkhead box protein C1 OS=Homo s... | 51 | 0.0007 | 47 | 39 | 63 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005720; C:nuclear heterochromatin; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IBA:RefGenome.::GO:0048844; P:artery morphogenesis; IBA:RefGenome.::GO:0001974; P:blood vessel remodeling; IBA:RefGenome.::GO:0007420; P:brain development; IBA:RefGenome.::GO:0043010; P:camera-type eye development; IBA:RefGenome.::GO:0060038; P:cardiac muscle cell proliferation; IBA:RefGenome.::GO:0030199; P:collagen fibril organization; IBA:RefGenome.::GO:0035050; P:embryonic heart tube development; IBA:RefGenome.::GO:0008354; P:germ cell migration; IBA:RefGenome.::GO:0030203; P:glycosaminoglycan metabolic process; IBA:RefGenome.::GO:0032808; P:lacrimal gland development; IBA:RefGenome.::GO:0001946; P:lymphangiogenesis; IBA:RefGenome.::GO:0001656; P:metanephros development; IBA:RefGenome.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; IBA:RefGenome.::GO:0007219; P:Notch signaling pathway; IBA:RefGenome.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:UniProtKB.::GO:0001503; P:ossification; IBA:RefGenome.::GO:0001541; P:ovarian follicle development; IBA:RefGenome.::GO:0048343; P:paraxial mesodermal cell fate commitment; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0050880; P:regulation of blood vessel size; IBA:RefGenome.::GO:0046620; P:regulation of organ growth; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0001756; P:somitogenesis; IBA:RefGenome.::GO:0001657; P:ureteric bud development; IBA:RefGenome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IBA:RefGenome.::GO:0001570; P:vasculogenesis; IBA:RefGenome.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IBA:RefGenome. | 111 | Q9PVZ3 | 492 | FXC1A_XENLA Forkhead box protein C1-A OS=Xeno... | 51 | 0.0007 | 47 | 39 | 63 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IMP:UniProtKB.::GO:0007498; P:mesoderm development; IMP:UniProtKB.::GO:0048793; P:pronephros development; IEP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB. | 112 | Q32NP8 | 495 | FXC1B_XENLA Forkhead box protein C1-B OS=Xeno... | 51 | 0.0007 | 46.6 | 39 | 63 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; ISS:UniProtKB.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB. | 113 | Q12946 | 379 | FOXF1_HUMAN Forkhead box protein F1 OS=Homo s... | 74 | 0.0007 | 46.6 | 31 | 53 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0060446; P:branching involved in open tracheal system development; IMP:DFLAT.::GO:0003214; P:cardiac left ventricle morphogenesis; IMP:DFLAT.::GO:0048613; P:embryonic ectodermal digestive tract morphogenesis; IMP:DFLAT.::GO:0003197; P:endocardial cushion development; IMP:DFLAT.::GO:0001701; P:in utero embryonic development; IMP:DFLAT.::GO:0060426; P:lung vasculature development; IMP:DFLAT.::GO:0007494; P:midgut development; IMP:DFLAT.::GO:0031016; P:pancreas development; IMP:DFLAT.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0072189; P:ureter development; IMP:DFLAT.::GO:0060841; P:venous blood vessel development; IMP:DFLAT. | 114 | O00358 | 373 | FOXE1_HUMAN Forkhead box protein E1 OS=Homo s... | 51 | 0.0008 | 46.2 | 39 | 57 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0048562; P:embryonic organ morphogenesis; ISS:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.::GO:0060022; P:hard palate development; IMP:UniProtKB.::GO:0002089; P:lens morphogenesis in camera-type eye; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0060465; P:pharynx development; IEP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060023; P:soft palate development; IMP:UniProtKB.::GO:0048538; P:thymus development; IEP:UniProtKB.::GO:0030878; P:thyroid gland development; IMP:UniProtKB.::GO:0006590; P:thyroid hormone generation; ISS:UniProtKB. | 115 | Q28F43 | 334 | FOXN2_XENTR Forkhead box protein N2 OS=Xenopu... | 51 | 0.0008 | 46.2 | 33 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 116 | Q66J77 | 430 | FOXN2_XENLA Forkhead box protein N2 OS=Xenopu... | 51 | 0.0009 | 46.2 | 33 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 117 | A1L1S5 | 380 | FOXF1_DANRE Forkhead box protein F1 OS=Danio ... | 74 | 0.001 | 46.2 | 31 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 118 | Q499D0 | 457 | FOXN3_MOUSE Forkhead box protein N3 OS=Mus mu... | 55 | 0.001 | 46.2 | 31 | 60 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 119 | Q5M7L9 | 369 | FOXD3_XENTR Forkhead box protein D3 OS=Xenopu... | 96 | 0.001 | 45.8 | 31 | 51 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.::GO:0051216; P:cartilage development; IBA:RefGenome.::GO:0048484; P:enteric nervous system development; IBA:RefGenome.::GO:0050935; P:iridophore differentiation; IBA:RefGenome.::GO:0001822; P:kidney development; IBA:RefGenome.::GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.::GO:0030318; P:melanocyte differentiation; IBA:RefGenome.::GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; ISS:UniProtKB.::GO:0001755; P:neural crest cell migration; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048485; P:sympathetic nervous system development; IBA:RefGenome. | 120 | Q9BZS1 | 431 | FOXP3_HUMAN Forkhead box protein P3 OS=Homo s... | 51 | 0.001 | 45.8 | 39 | 61 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; NAS:UniProtKB.::GO:0051525; F:NFAT protein binding; IPI:UniProtKB.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0003714; F:transcription corepressor activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001782; P:B cell homeostasis; IBA:RefGenome.::GO:0021549; P:cerebellum development; IBA:RefGenome.::GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0002262; P:myeloid cell homeostasis; IBA:RefGenome.::GO:0046007; P:negative regulation of activated T cell proliferation; NAS:UniProtKB.::GO:0002677; P:negative regulation of chronic inflammatory response; IBA:RefGenome.::GO:0032792; P:negative regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; IDA:UniProtKB.::GO:0035067; P:negative regulation of histone acetylation; IBA:RefGenome.::GO:0031064; P:negative regulation of histone deacetylation; IGI:BHF-UCL.::GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IBA:RefGenome.::GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; IDA:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; IMP:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; IDA:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; IDA:UniProtKB.::GO:0032714; P:negative regulation of interleukin-5 production; IBA:RefGenome.::GO:0032715; P:negative regulation of interleukin-6 production; IBA:RefGenome.::GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IBA:RefGenome.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IBA:RefGenome.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IBA:RefGenome.::GO:0002851; P:positive regulation of peripheral T cell tolerance induction; IBA:RefGenome.::GO:0002669; P:positive regulation of T cell anergy; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0032914; P:positive regulation of transforming growth factor beta1 production; IBA:RefGenome.::GO:0009791; P:post-embryonic development; IBA:RefGenome.::GO:0048302; P:regulation of isotype switching to IgG isotypes; IBA:RefGenome.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0043029; P:T cell homeostasis; NAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IBA:RefGenome.::GO:0002513; P:tolerance induction to self antigen; IBA:RefGenome. | 121 | Q6U8D7 | 431 | FOXP3_MACFA Forkhead box protein P3 OS=Macaca... | 51 | 0.001 | 45.8 | 39 | 61 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0051525; F:NFAT protein binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.::GO:0032693; P:negative regulation of interleukin-10 production; ISS:UniProtKB.::GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; ISS:UniProtKB.::GO:0032703; P:negative regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032713; P:negative regulation of interleukin-4 production; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0002725; P:negative regulation of T cell cytokine production; ISS:UniProtKB.::GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042110; P:T cell activation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
