| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P0C0V0 | 474 | DEGP_ECOLI Periplasmic serine endoprotease De... | 291 | 0.00000000008 | 69.3 | 23 | 46 | GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoliWiki.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004252; F:serine-type endopeptidase activity; IDA:EcoliWiki. | | | | | | | | | | GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:EcoliWiki.::GO:0006457; P:protein folding; IMP:EcoliWiki.::GO:0006979; P:response to oxidative stress; IEP:EcoliWiki.::GO:0009266; P:response to temperature stimulus; IEP:EcoliWiki. | 32 | P0C0V1 | 474 | DEGP_ECO57 Periplasmic serine endoprotease De... | 291 | 0.00000000008 | 69.3 | 23 | 46 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0009266; P:response to temperature stimulus; ISS:UniProtKB. | 33 | P73354 | 452 | HTRA_SYNY3 Putative serine protease HtrA OS=S... | 301 | 0.00000000009 | 69.3 | 23 | 45 | GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 34 | Q8YG32 | 513 | DEGPL_BRUME Probable periplasmic serine endop... | 261 | 0.0000000001 | 69.3 | 28 | 46 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 35 | P0A3Z5 | 513 | DEGPL_BRUSU Probable periplasmic serine endop... | 261 | 0.0000000001 | 68.9 | 28 | 46 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 36 | P0C114 | 513 | DEGPL_BRUAB Probable periplasmic serine endop... | 261 | 0.0000000001 | 68.9 | 28 | 46 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 37 | Q2YMX6 | 513 | DEGPL_BRUA2 Probable periplasmic serine endop... | 261 | 0.0000000001 | 68.9 | 28 | 46 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 38 | Q9D236 | 459 | HTRA3_MOUSE Serine protease HTRA3 OS=Mus musc... | 331 | 0.0000000002 | 68.6 | 26 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 39 | D3ZA76 | 459 | HTRA3_RAT Serine protease HTRA3 OS=Rattus nor... | 331 | 0.0000000002 | 68.6 | 26 | 45 | GO:0005576; C:extracellular region; IEA:InterPro. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 40 | P26982 | 475 | DEGP_SALTY Periplasmic serine endoprotease De... | 291 | 0.0000000003 | 67.8 | 23 | 45 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0009266; P:response to temperature stimulus; ISS:UniProtKB. | 41 | Q4KGQ4 | 476 | DEGPL_PSEF5 Probable periplasmic serine endop... | 153 | 9.5 | 33.9 | 23 | 40 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 42 | A6YFB5 | 459 | HTRA1_XENLA Serine protease HTRA1 OS=Xenopus ... | 314 | 0.0000000006 | 66.6 | 24 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 43 | A4XSC0 | 474 | DEGPL_PSEMY Probable periplasmic serine endop... | 161 | 0.77 | 37.4 | 24 | 40 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 44 | A5W8F5 | 477 | DEGPL_PSEP1 Probable periplasmic serine endop... | 395 | 0.0000000007 | 66.2 | 24 | 40 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 45 | B1J4D7 | 479 | DEGPL_PSEPW Probable periplasmic serine endop... | 388 | 0.000000001 | 65.9 | 24 | 43 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 46 | Q6GMI0 | 479 | HTR1A_DANRE Serine protease HTRA1A OS=Danio r... | 314 | 0.000000002 | 65.1 | 24 | 44 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 47 | F1N152 | 487 | HTRA1_BOVIN Serine protease HTRA1 OS=Bos taur... | 318 | 0.000000002 | 64.7 | 23 | 44 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 48 | B0KV30 | 477 | DEGPL_PSEPG Probable periplasmic serine endop... | 153 | 6.5 | 34.3 | 22 | 39 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 49 | O43464 | 458 | HTRA2_HUMAN Serine protease HTRA2, mitochondr... | 282 | 0.000000003 | 64.3 | 28 | 44 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0005758; C:mitochondrial intermembrane space; IDA:MGI.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; TAS:UniProtKB.::GO:0051082; F:unfolded protein binding; NAS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0071363; P:cellular response to growth factor stimulus; IMP:UniProtKB.::GO:0006923; P:cleavage of cytoskeletal proteins involved in apoptosis; TAS:UniProtKB.::GO:0097194; P:execution phase of apoptosis; TAS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0006950; P:response to stress; TAS:UniProtKB. | 50 | P45129 | 466 | HTOA_HAEIN Probable periplasmic serine protea... | 301 | 0.000000003 | 64.3 | 24 | 44 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 51 | A0JNK3 | 458 | HTRA2_BOVIN Serine protease HTRA2, mitochondr... | 287 | 0.000000003 | 64.3 | 28 | 43 | GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 52 | A4IHA1 | 460 | HTRA1_XENTR Serine protease HTRA1 OS=Xenopus ... | 314 | 0.000000004 | 64.3 | 25 | 46 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 53 | Q48EU9 | 479 | DEGPL_PSE14 Probable periplasmic serine endop... | 381 | 0.000000005 | 63.5 | 24 | 42 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 54 | Q2SL36 | 469 | DEGPL_HAHCH Probable periplasmic serine endop... | 386 | 0.000000009 | 62.8 | 24 | 44 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 55 | Q9JIY5 | 458 | HTRA2_MOUSE Serine protease HTRA2, mitochondr... | 286 | 0.00000001 | 62.8 | 28 | 42 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0048666; P:neuron development; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI. | 56 | P83105 | 476 | HTRA4_HUMAN Serine protease HTRA4 OS=Homo sap... | 296 | 0.00000001 | 62.8 | 24 | 44 | GO:0005576; C:extracellular region; IEA:InterPro. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 57 | A2RT60 | 483 | HTRA4_MOUSE Serine protease HTRA4 OS=Mus musc... | 292 | 0.00000001 | 62.4 | 24 | 44 | GO:0005576; C:extracellular region; IEA:InterPro. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 58 | A9JRB3 | 476 | HTR1B_DANRE Serine protease HTRA1B OS=Danio r... | 310 | 0.00000002 | 62 | 25 | 45 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 59 | Q92743 | 480 | HTRA1_HUMAN Serine protease HTRA1 OS=Homo sap... | 318 | 0.00000002 | 62 | 23 | 44 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; TAS:ProtInc. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 60 | D3ZKF5 | 488 | HTRA4_RAT Serine protease HTR4 OS=Rattus norv... | 284 | 0.00000002 | 61.6 | 24 | 45 | GO:0005576; C:extracellular region; IEA:InterPro. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 61 | B4QZU6 | 422 | HTRA2_DROSI Serine protease HTRA2, mitochondr... | 317 | 0.00000003 | 60.8 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
