| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations | 
					1 | Q7S8C2 | 137 | MED21_NEUCR Mediator of RNA polymerase II tra... | 137 | 6e-50 | 162 | 61 | 78 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | A1C712 | 189 | MED21_ASPCL Mediator of RNA polymerase II tra... | 175 | 1e-19 | 85.1 | 34 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q6FNK3 | 219 | MED21_CANGA Mediator of RNA polymerase II tra... | 132 | 6e-17 | 78.2 | 38 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | O94376 | 138 | MED21_SCHPO Mediator of RNA polymerase II tra... | 141 | 1e-16 | 76.6 | 30 | 56 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0016592; C:mediator complex; IDA:PomBase. |  |  |  |  |  |  |  |  |  | GO:0001104; F:RNA polymerase II transcription cofactor activity; ISS:PomBase. |  |  |  |  |  |  |  |  |  |  | 5 | Q2UF93 | 208 | MED21_ASPOR Mediator of RNA polymerase II tra... | 50 | 0.003 | 39.7 | 44 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | P47822 | 140 | MED21_YEAST Mediator of RNA polymerase II tra... | 107 | 5e-16 | 74.7 | 40 | 59 | GO:0070847; C:core mediator complex; IDA:SGD. |  |  |  |  |  |  |  |  |  | GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:SGD.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:SGD.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IMP:SGD. |  |  |  |  |  |  |  |  |  |  | 7 | Q6C5U8 | 140 | MED21_YARLI Mediator of RNA polymerase II tra... | 141 | 0.000000000000002 | 72.8 | 34 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q4X0I5 | 207 | MED21_ASPFU Mediator of RNA polymerase II tra... | 31 | 0.002 | 40.4 | 58 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | A1DHP1 | 207 | MED21_NEOFI Mediator of RNA polymerase II tra... | 192 | 0.00000000000002 | 71.2 | 32 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q75EX7 | 142 | MED21_ASHGO Mediator of RNA polymerase II tra... | 140 | 0.00000000000005 | 68.9 | 32 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | A2QC41 | 196 | MED21_ASPNC Mediator of RNA polymerase II tra... | 31 | 0.001 | 40.4 | 61 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q6CT76 | 143 | MED21_KLULA Mediator of RNA polymerase II tra... | 134 | 0.000000000003 | 63.9 | 33 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | A3LS24 | 164 | MED21_PICST Mediator of RNA polymerase II tra... | 163 | 0.00000000001 | 62.8 | 28 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q5ACU4 | 178 | MED21_CANAL Mediator of RNA polymerase II tra... | 172 | 0.000000005 | 55.1 | 27 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q5AZQ7 | 203 | MED21_EMENI Mediator of RNA polymerase II tra... | 40 | 0.0008 | 41.2 | 50 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q1DXC2 | 192 | MED21_COCIM Mediator of RNA polymerase II tra... | 31 | 0.002 | 39.7 | 58 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q6BQ63 | 173 | MED21_DEBHA Mediator of RNA polymerase II tra... | 172 | 0.00000008 | 52 | 26 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q0U499 | 155 | MED21_PHANO Mediator of RNA polymerase II tra... | 156 | 0.0000001 | 51.2 | 29 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q7ZTI5 | 145 | MED21_DANRE Mediator of RNA polymerase II tra... | 133 | 0.00002 | 45.1 | 29 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q13503 | 144 | MED21_HUMAN Mediator of RNA polymerase II tra... | 110 | 0.00006 | 43.5 | 32 | 50 | GO:0016592; C:mediator complex; IDA:MGI. |  |  |  |  |  |  |  |  |  | GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; IDA:MGI. |  |  |  |  |  |  |  |  |  | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. | 21 | Q2TBU8 | 144 | MED21_BOVIN Mediator of RNA polymerase II tra... | 110 | 0.00006 | 43.5 | 32 | 50 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q9CQ39 | 144 | MED21_MOUSE Mediator of RNA polymerase II tra... | 110 | 0.00007 | 43.5 | 32 | 50 | GO:0016592; C:mediator complex; IDA:MGI. |  |  |  |  |  |  |  |  |  | GO:0005515; F:protein binding; IPI:MGI. |  |  |  |  |  |  |  |  |  | GO:0001824; P:blastocyst development; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IC:MGI. | 23 | Q4R6N3 | 144 | MED21_MACFA Mediator of RNA polymerase II tra... | 110 | 0.00007 | 43.5 | 32 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q5RE46 | 144 | MED21_PONAB Mediator of RNA polymerase II tra... | 109 | 0.00009 | 43.1 | 32 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | Q9W5P1 | 142 | MED21_DROME Mediator of RNA polymerase II tra... | 113 | 0.019 | 37 | 31 | 46 | GO:0016592; C:mediator complex; IDA:UniProtKB. |  |  |  |  |  |  |  |  |  | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IMP:UniProtKB. |  |  |  |  |  |  |  |  |  |  | 26 | Q55BM1 | 1360 | Y0444_DICDI Probable inactive protein kinase ... | 109 | 0.37 | 34.3 | 26 | 52 |  |  |  |  |  |  |  |  |  |  | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  |  | 27 | Q16RX1 | 141 | MED21_AEDAE Mediator of RNA polymerase II tra... | 133 | 0.89 | 32.3 | 27 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q7PTL0 | 154 | MED21_ANOGA Mediator of RNA polymerase II tra... | 28 | 2.6 | 31.2 | 50 | 64 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q86YP4 | 633 | P66A_HUMAN Transcriptional repressor p66-alph... | 75 | 2.7 | 31.6 | 31 | 53 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016581; C:NuRD complex; IDA:UniProtKB. |  |  |  |  |  |  |  |  |  | GO:0030674; F:protein binding, bridging; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0006306; P:DNA methylation; TAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q7MQ29 | 130 | TATB_VIBVY Sec-independent protein translocas... | 63 | 4 | 30.4 | 37 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0008565; F:protein transporter activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0009306; P:protein secretion; IEA:InterPro.::GO:0043953; P:protein transport by the Tat complex; IEA:InterPro. | 31 | Q8DDQ3 | 130 | TATB_VIBVU Sec-independent protein translocas... | 63 | 4 | 30.4 | 37 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. |  |  |  |  |  |  |  |  |  | GO:0008565; F:protein transporter activity; IEA:InterPro. |  |  |  |  |  |  |  |  |  | GO:0009306; P:protein secretion; IEA:InterPro.::GO:0043953; P:protein transport by the Tat complex; IEA:InterPro. |