| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9Z272 | 770 | GIT1_RAT ARF GTPase-activating protein GIT1 O... | 67 | 0.00000005 | 58.5 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0031267; F:small GTPase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:RGD. | 92 | Q9Y2X7 | 761 | GIT1_HUMAN ARF GTPase-activating protein GIT1... | 67 | 0.00000006 | 58.5 | 37 | 51 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc. | 93 | Q68FF6 | 770 | GIT1_MOUSE ARF GTPase-activating protein GIT1... | 67 | 0.00000006 | 58.2 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 94 | Q14161 | 759 | GIT2_HUMAN ARF GTPase-activating protein GIT2... | 42 | 0.00000008 | 58.2 | 52 | 60 | GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc. | 95 | Q8BZ05 | 1703 | ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 71 | 0.0000001 | 57.8 | 44 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 96 | Q10165 | 923 | CNT6_SCHPO Probable ribosylation factor GTPas... | 50 | 0.0000005 | 55.8 | 42 | 60 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:PomBase. | 97 | Q8WWN8 | 1544 | ARAP3_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 71 | 0.0000005 | 55.8 | 38 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB. | 98 | Q4KLH5 | 561 | AGFG1_RAT Arf-GAP domain and FG repeat-contai... | 123 | 0.000003 | 53.1 | 30 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 99 | P52594 | 562 | AGFG1_HUMAN Arf-GAP domain and FG repeat-cont... | 123 | 0.000003 | 53.1 | 30 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 100 | Q8K2K6 | 561 | AGFG1_MOUSE Arf-GAP domain and FG repeat-cont... | 123 | 0.000003 | 53.1 | 30 | 45 | GO:0042995; C:cell projection; IDA:MGI.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0045109; P:intermediate filament organization; IMP:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007289; P:spermatid nucleus differentiation; IMP:MGI.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 101 | Q2TA45 | 562 | AGFG1_BOVIN Arf-GAP domain and FG repeat-cont... | 123 | 0.000003 | 52.8 | 30 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 102 | Q8R5G7 | 1538 | ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 66 | 0.000004 | 52.8 | 39 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 103 | P40956 | 396 | GTS1_YEAST Protein GTS1 OS=Saccharomyces cere... | 122 | 0.000005 | 52 | 32 | 48 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IMP:SGD.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0000989; F:transcription factor binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:SGD.::GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007624; P:ultradian rhythm; IMP:SGD. | 104 | Q80WC7 | 479 | AGFG2_MOUSE Arf-GAP domain and FG repeat-cont... | 151 | 0.0002 | 47.4 | 27 | 43 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 105 | Q1ZXH8 | 1632 | GXCDD_DICDI Guanine exchange factor for Rac 3... | 44 | 0.0004 | 46.2 | 39 | 64 | GO:0005938; C:cell cortex; IMP:dictyBase.::GO:0032009; C:early phagosome; IMP:dictyBase.::GO:0005626; C:insoluble fraction; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:dictyBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:dictyBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IPI:dictyBase. | 106 | O95081 | 481 | AGFG2_HUMAN Arf-GAP domain and FG repeat-cont... | 141 | 0.0007 | 45.4 | 27 | 45 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 107 | Q54DK4 | 1352 | AK1_DICDI Alpha-protein kinase 1 OS=Dictyoste... | 78 | 0.15 | 38.1 | 28 | 50 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 108 | Q703G9 | 972 | POLS_IPNVS Structural polyprotein OS=Infectio... | 224 | 2.5 | 34.3 | 23 | 39 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0019012; C:virion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 109 | Q99NB9 | 1304 | SF3B1_MOUSE Splicing factor 3B subunit 1 OS=M... | 38 | 3 | 33.9 | 34 | 55 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 110 | O75533 | 1304 | SF3B1_HUMAN Splicing factor 3B subunit 1 OS=H... | 38 | 3 | 33.9 | 34 | 55 | GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005689; C:U12-type spliceosomal complex; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0000398; P:nuclear mRNA splicing, via spliceosome; NAS:UniProtKB. | 111 | P35207 | 1287 | SKI2_YEAST Antiviral helicase SKI2 OS=Sacchar... | 62 | 4.6 | 33.5 | 37 | 47 | GO:0055087; C:Ski complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 112 | P22495 | 972 | POLS_IPNVN Structural polyprotein OS=Infectio... | 119 | 4.9 | 33.1 | 31 | 42 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0019028; C:viral capsid; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 113 | O57683 | 1307 | SF3B1_XENLA Splicing factor 3B subunit 1 OS=X... | 38 | 6.3 | 32.7 | 34 | 58 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 114 | Q96N67 | 2140 | DOCK7_HUMAN Dedicator of cytokinesis protein ... | 59 | 7.4 | 32.7 | 34 | 51 | GO:0030424; C:axon; TAS:BHF-UCL.::GO:0045178; C:basal part of cell; TAS:BHF-UCL.::GO:0030426; C:growth cone; TAS:BHF-UCL. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IDA:BHF-UCL.::GO:0007409; P:axonogenesis; IMP:BHF-UCL.::GO:0045200; P:establishment of neuroblast polarity; IMP:BHF-UCL.::GO:0000226; P:microtubule cytoskeleton organization; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL. |
