| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q3UHD9 | 1186 | AGAP2_MOUSE Arf-GAP with GTPase, ANK repeat a... | 97 | 0.0000000000002 | 76.3 | 39 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:MGI.::GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 62 | Q8CGU4 | 1186 | AGAP2_RAT Arf-GAP with GTPase, ANK repeat and... | 97 | 0.0000000000002 | 75.9 | 39 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 63 | Q8TDY4 | 903 | ASAP3_HUMAN Arf-GAP with SH3 domain, ANK repe... | 88 | 0.0000000000003 | 75.1 | 39 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 64 | Q5U464 | 904 | ASAP3_MOUSE Arf-GAP with SH3 domain, ANK repe... | 93 | 0.0000000000003 | 75.1 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 65 | Q9C6C3 | 776 | AGD2_ARATH ADP-ribosylation factor GTPase-act... | 58 | 0.0000000000008 | 73.9 | 50 | 69 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 66 | Q9SMX5 | 775 | AGD4_ARATH ADP-ribosylation factor GTPase-act... | 48 | 0.000000000001 | 73.6 | 56 | 73 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 67 | Q8VHH5 | 910 | AGAP3_MOUSE Arf-GAP with GTPase, ANK repeat a... | 69 | 0.000000000003 | 72 | 43 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 68 | Q6NRL1 | 864 | AGAP1_XENLA Arf-GAP with GTPase, ANK repeat a... | 72 | 0.000000000004 | 71.6 | 44 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 69 | Q96P47 | 875 | AGAP3_HUMAN Arf-GAP with GTPase, ANK repeat a... | 69 | 0.000000000007 | 70.9 | 42 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 70 | Q8BXK8 | 857 | AGAP1_MOUSE Arf-GAP with GTPase, ANK repeat a... | 80 | 0.00000000001 | 70.1 | 39 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 71 | Q9UPQ3 | 857 | AGAP1_HUMAN Arf-GAP with GTPase, ANK repeat a... | 80 | 0.00000000001 | 70.1 | 39 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 72 | Q9NPF8 | 381 | ADAP2_HUMAN Arf-GAP with dual PH domain-conta... | 84 | 0.00000000002 | 68.9 | 43 | 61 | GO:0005740; C:mitochondrial envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0030674; F:protein binding, bridging; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; IEP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 73 | Q8RXE7 | 649 | AGD14_ARATH Probable ADP-ribosylation factor ... | 82 | 0.00000000004 | 68.2 | 34 | 57 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 74 | Q04412 | 482 | AGE1_YEAST ADP-ribosylation factor GTPase-act... | 72 | 0.00000000008 | 67 | 42 | 67 | GO:0005768; C:endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IGI:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 75 | Q9JK15 | 376 | ADAP2_RAT Arf-GAP with dual PH domain-contain... | 75 | 0.0000000002 | 65.5 | 44 | 56 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005740; C:mitochondrial envelope; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IMP:RGD.::GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 76 | Q8R2V5 | 381 | ADAP2_MOUSE Arf-GAP with dual PH domain-conta... | 70 | 0.0000000002 | 65.5 | 47 | 59 | GO:0005740; C:mitochondrial envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; NAS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 77 | Q5VW22 | 663 | AGAP6_HUMAN Arf-GAP with GTPase, ANK repeat a... | 56 | 0.0000000003 | 65.5 | 45 | 66 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 78 | Q8TF27 | 550 | AGA11_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.0000000005 | 64.7 | 37 | 56 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 79 | Q5T2P9 | 658 | AGA10_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.0000000006 | 64.7 | 35 | 54 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 80 | Q5VTM2 | 703 | AGAP9_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.000000001 | 63.9 | 35 | 54 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 81 | Q96P64 | 663 | AGAP4_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.000000001 | 63.9 | 35 | 56 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 82 | Q5VUJ5 | 663 | AGAP7_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.000000001 | 63.9 | 35 | 56 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 83 | Q96P48 | 1450 | ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 53 | 0.000000002 | 63.5 | 53 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 84 | Q9UUE2 | 870 | CSX2_SCHPO Protein csx2 OS=Schizosaccharomyce... | 68 | 0.000000002 | 63.5 | 32 | 57 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071276; P:cellular response to cadmium ion; IMP:PomBase.::GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase. | 85 | Q5SRD3 | 663 | AGAP8_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.000000004 | 62 | 34 | 54 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 86 | A8MT82 | 671 | CTLFB_HUMAN Putative centaurin-gamma-like fam... | 79 | 0.00000002 | 60.1 | 34 | 54 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 87 | Q4LDD4 | 1452 | ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 53 | 0.00000002 | 60.5 | 51 | 58 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 88 | Q8WZ64 | 1704 | ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 71 | 0.00000002 | 60.1 | 45 | 55 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 89 | Q9JLQ2 | 708 | GIT2_MOUSE ARF GTPase-activating protein GIT2... | 67 | 0.00000003 | 59.3 | 40 | 49 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 90 | A6NIR3 | 686 | AGAP5_HUMAN Arf-GAP with GTPase, ANK repeat a... | 79 | 0.00000003 | 59.3 | 34 | 54 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 91 | Q9Z272 | 770 | GIT1_RAT ARF GTPase-activating protein GIT1 O... | 67 | 0.00000005 | 58.5 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0031267; F:small GTPase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:RGD. |
