| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O29627 | 326 | LEU3_ARCFU 3-isopropylmalate dehydrogenase OS... | 330 | 2e-86 | 271 | 44 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 32 | Q68FX0 | 385 | IDH3B_RAT Isocitrate dehydrogenase [NAD] subu... | 337 | 3e-85 | 270 | 42 | 65 | GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IC:RGD. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006102; P:isocitrate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. | 33 | Q28479 | 385 | IDH3B_MACFA Isocitrate dehydrogenase [NAD] su... | 337 | 1e-84 | 269 | 41 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 34 | O43837 | 385 | IDH3B_HUMAN Isocitrate dehydrogenase [NAD] su... | 337 | 3e-84 | 268 | 41 | 65 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006102; P:isocitrate metabolic process; TAS:ProtInc.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome. | 35 | Q93353 | 379 | IDH3B_CAEEL Probable isocitrate dehydrogenase... | 388 | 3e-83 | 265 | 39 | 62 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 36 | Q5RBT4 | 385 | IDH3B_PONAB Isocitrate dehydrogenase [NAD] su... | 337 | 9e-83 | 264 | 41 | 65 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 37 | Q1RJU4 | 483 | IDH_RICBR Isocitrate dehydrogenase [NADP] OS=... | 339 | 1e-80 | 261 | 43 | 63 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 38 | Q8BPC6 | 396 | IDHG2_MOUSE Probable isocitrate dehydrogenase... | 327 | 2e-80 | 258 | 42 | 63 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 39 | O27441 | 329 | LEU3_METTH 3-isopropylmalate dehydrogenase OS... | 330 | 2e-78 | 251 | 43 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 40 | Q4QQT5 | 395 | IDHG2_RAT Probable isocitrate dehydrogenase [... | 327 | 1e-77 | 251 | 40 | 63 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 41 | Q68XA5 | 483 | IDH_RICTY Isocitrate dehydrogenase [NADP] OS=... | 339 | 2e-77 | 253 | 42 | 62 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 42 | Q9ZDR0 | 483 | IDH_RICPR Isocitrate dehydrogenase [NADP] OS=... | 339 | 2e-77 | 253 | 42 | 62 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 43 | Q4UKR1 | 483 | IDH_RICFE Isocitrate dehydrogenase [NADP] OS=... | 339 | 5e-77 | 252 | 42 | 62 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 44 | Q92IR7 | 483 | IDH_RICCN Isocitrate dehydrogenase [NADP] OS=... | 339 | 1e-76 | 251 | 42 | 62 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 45 | Q58130 | 333 | LEU3_METJA 3-isopropylmalate/3-methylmalate d... | 336 | 1e-72 | 236 | 40 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 46 | P50455 | 337 | LEU3_SULTO 3-isopropylmalate dehydrogenase OS... | 343 | 7e-71 | 231 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 47 | Q58991 | 347 | AKSF_METJA Homoisocitrate dehydrogenase OS=JC... | 346 | 1e-68 | 226 | 41 | 59 | | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:InterPro.::GO:0047046; F:homoisocitrate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:InterPro. | 48 | Q9UXB2 | 336 | LEU3_SULSO 3-isopropylmalate dehydrogenase OS... | 339 | 2e-67 | 223 | 39 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 49 | P40495 | 371 | LYS12_YEAST Homoisocitrate dehydrogenase, mit... | 350 | 1e-60 | 206 | 39 | 57 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0047046; F:homoisocitrate dehydrogenase activity; IDA:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW. | 50 | O14104 | 362 | LYS12_SCHPO Probable homoisocitrate dehydroge... | 364 | 5e-58 | 199 | 36 | 55 | GO:0005739; C:mitochondrion; ISS:PomBase. | | | | | | | | | | GO:0047046; F:homoisocitrate dehydrogenase activity; ISS:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0009085; P:lysine biosynthetic process; IMP:PomBase. | 51 | O29610 | 412 | IDH_ARCFU Isocitrate dehydrogenase [NADP] OS=... | 405 | 5e-57 | 197 | 34 | 50 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 52 | B1VG35 | 339 | LEU3_CORU7 3-isopropylmalate dehydrogenase OS... | 319 | 8e-55 | 189 | 38 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 53 | C3PFX5 | 339 | LEU3_CORA7 3-isopropylmalate dehydrogenase OS... | 351 | 9e-54 | 187 | 38 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 54 | P08200 | 416 | IDH_ECOLI Isocitrate dehydrogenase [NADP] OS=... | 413 | 1e-53 | 188 | 32 | 49 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0022900; P:electron transport chain; IMP:EcoliWiki.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IDA:EcoliWiki. | 55 | A4QDP9 | 340 | LEU3_CORGB 3-isopropylmalate dehydrogenase OS... | 313 | 1e-52 | 184 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 56 | P94631 | 340 | LEU3_CORGL 3-isopropylmalate dehydrogenase OS... | 313 | 2e-52 | 183 | 37 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 57 | Q9ZH99 | 427 | IDH_COXBU Isocitrate dehydrogenase [NADP] OS=... | 415 | 8e-52 | 184 | 32 | 48 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 58 | P41560 | 415 | IDH1_COLMA Isocitrate dehydrogenase [NADP] 1 ... | 407 | 2e-51 | 183 | 31 | 49 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 59 | Q8FPV5 | 340 | LEU3_COREF 3-isopropylmalate dehydrogenase OS... | 313 | 3e-51 | 180 | 36 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 60 | Q9ZN36 | 425 | IDH_HELPJ Isocitrate dehydrogenase [NADP] OS=... | 420 | 9e-51 | 181 | 32 | 49 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 61 | O67480 | 426 | IDH_AQUAE Isocitrate dehydrogenase [NADP] OS=... | 389 | 1e-50 | 181 | 32 | 51 | | | | | | | | | | | GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. |
