| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | A5PK00 | 386 | VPS36_BOVIN Vacuolar protein-sorting-associat... | 336 | 2e-40 | 155 | 33 | 52 | GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q91XD6 | 386 | VPS36_MOUSE Vacuolar protein-sorting-associat... | 337 | 4e-39 | 152 | 32 | 51 | GO:0005770; C:late endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; IDA:MGI. | | | | | | | | | | GO:0016197; P:endosome transport; IC:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | P0C0A2 | 386 | VPS36_RAT Vacuolar protein-sorting-associated... | 337 | 4e-39 | 152 | 32 | 51 | GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q86VN1 | 386 | VPS36_HUMAN Vacuolar protein-sorting-associat... | 336 | 2e-38 | 150 | 32 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q7ZVK4 | 382 | VPS36_DANRE Vacuolar protein-sorting-associat... | 313 | 6e-38 | 148 | 33 | 54 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 6 | Q6DDF4 | 388 | VPS36_XENLA Vacuolar protein-sorting-associat... | 336 | 2e-37 | 147 | 32 | 50 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 7 | O43038 | 467 | VPS36_SCHPO Vacuolar protein-sorting-associat... | 611 | 8e-36 | 144 | 24 | 37 | GO:0000814; C:ESCRT II complex; ISS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006900; P:membrane budding; IC:PomBase.::GO:0045053; P:protein retention in Golgi apparatus; ISS:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 8 | Q06696 | 566 | VPS36_YEAST Vacuolar protein-sorting-associat... | 639 | 2e-34 | 141 | 24 | 42 | GO:0000814; C:ESCRT II complex; IDA:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IPI:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IC:SGD. | 9 | Q9FF81 | 440 | VPS36_ARATH Vacuolar protein sorting-associat... | 316 | 1e-31 | 132 | 34 | 50 | GO:0000814; C:ESCRT II complex; ISS:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 10 | Q9VU87 | 399 | VPS36_DROME Vacuolar protein-sorting-associat... | 317 | 1e-23 | 107 | 30 | 45 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0003730; F:mRNA 3'-UTR binding; IDA:FlyBase. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; IMP:FlyBase.::GO:0008593; P:regulation of Notch signaling pathway; IEP:FlyBase. | 11 | Q54T18 | 611 | VPS36_DICDI Vacuolar protein-sorting-associat... | 46 | 2.1 | 35 | 37 | 61 | GO:0000814; C:ESCRT II complex; ISS:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0006605; P:protein targeting; ISS:dictyBase. | 12 | Q9HLX6 | 493 | LONH_THEAC Putative lon protease homolog OS=N... | 166 | 0.006 | 43.1 | 28 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016851; F:magnesium chelatase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | P58275 | 495 | LONH_THEVO Putative lon protease homolog OS=1... | 166 | 0.015 | 42 | 28 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016851; F:magnesium chelatase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:InterPro.::GO:0015979; P:photosynthesis; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 14 | Q5U303 | 693 | TAB2_RAT TGF-beta-activated kinase 1 and MAP3... | 81 | 0.077 | 39.7 | 31 | 43 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0070530; F:K63-linked polyubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB. | 15 | Q99K90 | 693 | TAB2_MOUSE TGF-beta-activated kinase 1 and MA... | 82 | 0.078 | 39.7 | 32 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0070530; F:K63-linked polyubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB. | 16 | Q9NYJ8 | 693 | TAB2_HUMAN TGF-beta-activated kinase 1 and MA... | 81 | 0.13 | 39.3 | 31 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 17 | Q8TAT6 | 608 | NPL4_HUMAN Nuclear protein localization prote... | 38 | 0.27 | 38.1 | 47 | 55 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; ISS:HGNC.::GO:0030433; P:ER-associated protein catabolic process; ISS:HGNC.::GO:0007030; P:Golgi organization; ISS:HGNC. | 18 | Q6NZP1 | 1069 | ZRAB3_MOUSE Zinc finger Ran-binding domain-co... | 29 | 0.27 | 38.1 | 55 | 66 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | P58022 | 776 | LOXL2_MOUSE Lysyl oxidase homolog 2 OS=Mus mu... | 197 | 0.27 | 38.1 | 25 | 35 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0016641; F:oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | | 20 | Q5RFW2 | 711 | TAB2_DANRE TGF-beta-activated kinase 1 and MA... | 78 | 0.41 | 37.4 | 33 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060027; P:convergent extension involved in gastrulation; IMP:ZFIN.::GO:0007507; P:heart development; IMP:UniProtKB. | 21 | O75808 | 1086 | CAN15_HUMAN Calpain-15 OS=Homo sapiens (Human... | 29 | 0.43 | 37.4 | 48 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 22 | Q95218 | 1594 | DMBT1_RABIT Deleted in malignant brain tumors... | 99 | 0.57 | 37.4 | 29 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; ISS:UniProtKB.::GO:0042589; C:zymogen granule membrane; ISS:UniProtKB. | | | | | | | | | | GO:0051636; F:Gram-negative bacterial cell surface binding; ISS:UniProtKB.::GO:0051637; F:Gram-positive bacterial cell surface binding; ISS:UniProtKB.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.::GO:0035375; F:zymogen binding; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 23 | Q8N5C8 | 712 | TAB3_HUMAN TGF-beta-activated kinase 1 and MA... | 25 | 0.66 | 37 | 56 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 24 | Q571K4 | 716 | TAB3_MOUSE TGF-beta-activated kinase 1 and MA... | 25 | 0.81 | 36.6 | 56 | 64 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 25 | Q7ZXH3 | 692 | TAB3_XENLA Mitogen-activated protein kinase k... | 44 | 0.84 | 36.6 | 39 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 26 | A5V6T7 | 314 | ACDH1_SPHWW Acetaldehyde dehydrogenase 1/2 OS... | 33 | 1.4 | 35.4 | 52 | 61 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0008774; F:acetaldehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 27 | Q5FWF4 | 1079 | ZRAB3_HUMAN Zinc finger Ran-binding domain-co... | 81 | 2 | 35.4 | 33 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 28 | Q9P219 | 2028 | DAPLE_HUMAN Protein Daple OS=Homo sapiens (Hu... | 135 | 2.2 | 35.4 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 29 | P0CP30 | 693 | NPL4_CRYNJ Nuclear protein localization prote... | 22 | 2.4 | 35 | 59 | 64 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 30 | P0CP31 | 693 | NPL4_CRYNB Nuclear protein localization prote... | 22 | 2.4 | 35 | 59 | 64 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 31 | P60670 | 608 | NPL4_MOUSE Nuclear protein localization prote... | 38 | 4.1 | 34.3 | 42 | 53 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; ISS:HGNC.::GO:0030433; P:ER-associated protein catabolic process; ISS:HGNC.::GO:0007030; P:Golgi organization; ISS:HGNC. |
