rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q5XHY7 | 523 | STAM2_RAT Signal transducing adapter molecule... | 50 | 0.9 | 36.2 | 36 | 54 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 32 | Q96KQ4 | 1090 | ASPP1_HUMAN Apoptosis-stimulating of p53 prot... | 55 | 0.001 | 46.2 | 45 | 62 | GO:0005737; C:cytoplasm; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB. | 33 | O43281 | 561 | EFS_HUMAN Embryonal Fyn-associated substrate ... | 96 | 0.001 | 45.8 | 36 | 50 | GO:0005737; C:cytoplasm; TAS:ProtInc. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc. | 34 | Q6CHN0 | 1136 | SLA1_YARLI Actin cytoskeleton-regulatory comp... | 63 | 3.5 | 34.7 | 30 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 35 | P0CR79 | 660 | HSE1_CRYNB Class E vacuolar protein-sorting m... | 58 | 0.001 | 45.4 | 36 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 36 | Q64355 | 560 | EFS_MOUSE Embryonal Fyn-associated substrate ... | 66 | 0.001 | 45.1 | 39 | 53 | | | | | | | | | | | GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 37 | Q8NFA2 | 376 | NOXO1_HUMAN NADPH oxidase organizer 1 OS=Homo... | 109 | 0.002 | 44.7 | 28 | 41 | GO:0043020; C:NADPH oxidase complex; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; TAS:BHF-UCL. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.::GO:0060263; P:regulation of respiratory burst; TAS:BHF-UCL. | 38 | O01498 | 457 | STAM1_CAEEL Signal transducing adapter molecu... | 74 | 0.007 | 42.7 | 36 | 51 | GO:0044441; C:cilium part; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0033565; C:ESCRT-0 complex; IPI:WormBase. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:WormBase.::GO:0043130; F:ubiquitin binding; IDA:WormBase. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:WormBase.::GO:0048013; P:ephrin receptor signaling pathway; IGI:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB. | 39 | P0CR78 | 660 | HSE1_CRYNJ Class E vacuolar protein-sorting m... | 57 | 0.002 | 45.1 | 37 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 40 | O93436 | 468 | STAM2_CHICK Signal transducing adapter molecu... | 84 | 0.35 | 37.4 | 33 | 52 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 41 | O89100 | 322 | GRAP2_MOUSE GRB2-related adaptor protein 2 OS... | 59 | 0.002 | 44.3 | 32 | 58 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 42 | O75791 | 330 | GRAP2_HUMAN GRB2-related adapter protein 2 OS... | 59 | 0.002 | 44.3 | 32 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 43 | P00528 | 552 | SRC64_DROME Tyrosine-protein kinase Src64B OS... | 89 | 0.002 | 44.7 | 30 | 49 | GO:0045172; C:germline ring canal; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0008302; P:female germline ring canal formation, actin assembly; IMP:FlyBase.::GO:0008335; P:female germline ring canal stabilization; IMP:FlyBase.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030046; P:parallel actin filament bundle assembly; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IGI:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase. | 44 | P34109 | 1109 | MYOD_DICDI Myosin ID heavy chain OS=Dictyoste... | 52 | 0.86 | 36.6 | 33 | 63 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 45 | Q02977 | 536 | YRK_CHICK Proto-oncogene tyrosine-protein kin... | 35 | 0.008 | 42.7 | 51 | 74 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 46 | Q61644 | 441 | PACN1_MOUSE Protein kinase C and casein kinas... | 58 | 0.003 | 43.9 | 38 | 53 | GO:0030137; C:COPI-coated vesicle; IDA:MGI. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI. | 47 | P10936 | 537 | YES_XENLA Tyrosine-protein kinase Yes OS=Xeno... | 61 | 0.64 | 36.6 | 26 | 54 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 48 | Q9BY11 | 444 | PACN1_HUMAN Protein kinase C and casein kinas... | 58 | 0.003 | 43.9 | 38 | 53 | | | | | | | | | | | GO:0004672; F:protein kinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB. | 49 | Q5R411 | 444 | PACN1_PONAB Protein kinase C and casein kinas... | 58 | 0.003 | 43.9 | 38 | 53 | | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 50 | P07947 | 543 | YES_HUMAN Tyrosine-protein kinase Yes OS=Homo... | 62 | 0.56 | 37 | 26 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 51 | Q8TC17 | 118 | GRAPL_HUMAN GRB2-related adapter protein-like... | 54 | 0.003 | 41.6 | 31 | 57 | | | | | | | | | | | | | | | | | | | | | | 52 | P10569 | 1168 | MYSC_ACACA Myosin IC heavy chain OS=Acanthamo... | 56 | 0.19 | 38.5 | 36 | 57 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 53 | Q9Z0W5 | 441 | PACN1_RAT Protein kinase C and casein kinase ... | 58 | 0.003 | 43.9 | 38 | 53 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IDA:RGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 54 | F1LM93 | 541 | YES_RAT Tyrosine-protein kinase Yes OS=Rattus... | 59 | 1.9 | 35 | 25 | 54 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005154; F:epidermal growth factor receptor binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:RGD. | 55 | Q04736 | 541 | YES_MOUSE Tyrosine-protein kinase Yes OS=Mus ... | 62 | 0.34 | 37.7 | 26 | 55 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0015758; P:glucose transport; IDA:MGI. | 56 | Q2HDI2 | 1214 | MYO1_CHAGB Myosin-1 OS=6347 / NRRL 1970) (Soi... | 52 | 0.004 | 44.3 | 37 | 62 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 57 | P32790 | 1244 | SLA1_YEAST Actin cytoskeleton-regulatory comp... | 68 | 0.55 | 37 | 26 | 49 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0006897; P:endocytosis; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD. | 58 | A6ZKU1 | 1244 | SLA1_YEAS7 Actin cytoskeleton-regulatory comp... | 68 | 0.55 | 37 | 26 | 49 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 59 | Q09822 | 927 | CDC15_SCHPO Cell division control protein 15 ... | 120 | 0.88 | 36.6 | 25 | 43 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032178; C:medial membrane band; IDA:PomBase. | | | | | | | | | | GO:0043495; F:protein anchor; TAS:PomBase. | | | | | | | | | | GO:0030866; P:cortical actin cytoskeleton organization; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0061166; P:establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051125; P:regulation of actin nucleation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 60 | P09324 | 541 | YES_CHICK Tyrosine-protein kinase Yes OS=Gall... | 84 | 0.21 | 38.1 | 25 | 48 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 61 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 174 | 0.38 | 37.7 | 21 | 41 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. |