rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q9DDA9 | 477 | PACN2_XENLA Protein kinase C and casein kinas... | 100 | 4.8 | 33.9 | 26 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 212 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 35 | 0.49 | 37 | 43 | 71 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 213 | Q8N2Y8 | 1516 | RUSC2_HUMAN Iporin OS=Homo sapiens (Human). G... | 84 | 0.41 | 37.7 | 31 | 52 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 214 | Q2KJA1 | 368 | SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi... | 57 | 0.41 | 37 | 32 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 215 | Q75JD4 | 533 | Y1676_DICDI SH3 and FCH domain-containing pro... | 56 | 0.42 | 37.4 | 30 | 50 | | | | | | | | | | | | | | | | | | | | | | 216 | Q54CL3 | 570 | PEX13_DICDI Probable peroxisomal membrane pro... | 57 | 0.45 | 37.4 | 28 | 53 | GO:0005779; C:integral to peroxisomal membrane; ISS:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; ISS:dictyBase. | 217 | A2QW93 | 611 | HSE1_ASPNC Class E vacuolar protein-sorting m... | 84 | 0.46 | 37.4 | 31 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 218 | Q6CVA8 | 508 | HSE1_KLULA Class E vacuolar protein-sorting m... | 75 | 0.46 | 37 | 33 | 49 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 219 | Q99961 | 368 | SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu... | 57 | 0.49 | 37 | 32 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 220 | Q7ZYG4 | 214 | OSTF1_XENLA Osteoclast-stimulating factor 1 O... | 52 | 0.49 | 36.2 | 37 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 221 | P15054 | 587 | SRC_AVIS2 Tyrosine-protein kinase transformin... | 51 | 2 | 35 | 31 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 222 | Q91Z67 | 1071 | FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p... | 90 | 0.52 | 37.4 | 26 | 48 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 223 | Q8I1C0 | 369 | SH3G3_DROPS Endophilin-A OS=Drosophila pseudo... | 73 | 0.53 | 36.6 | 27 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 224 | O43125 | 296 | CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce... | 55 | 0.53 | 36.6 | 35 | 53 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 225 | Q5ZJJ9 | 202 | OSTF1_CHICK Osteoclast-stimulating factor 1 O... | 52 | 0.56 | 36.2 | 37 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 226 | Q62936 | 849 | DLG3_RAT Disks large homolog 3 OS=Rattus norv... | 42 | 0.62 | 37 | 43 | 62 | GO:0043198; C:dendritic shaft; IDA:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 227 | P70175 | 849 | DLG3_MOUSE Disks large homolog 3 OS=Mus muscu... | 42 | 0.62 | 37 | 43 | 62 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 228 | Q13882 | 451 | PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo ... | 77 | 0.63 | 36.6 | 32 | 53 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IDA:UniProtKB. | 229 | O00750 | 1634 | P3C2B_HUMAN Phosphatidylinositol 4-phosphate ... | 103 | 0.64 | 37 | 25 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 230 | Q6FN49 | 450 | HSE1_CANGA Class E vacuolar protein-sorting m... | 64 | 0.66 | 36.6 | 27 | 52 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 231 | Q9P7E8 | 857 | APP1_SCHPO Protein app1 OS=Schizosaccharomyce... | 62 | 0.67 | 37 | 32 | 52 | GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IC:PomBase. | 232 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 76 | 0.67 | 36.6 | 30 | 49 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 233 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 107 | 0.68 | 36.6 | 25 | 46 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 234 | Q9Y5K6 | 639 | CD2AP_HUMAN CD2-associated protein OS=Homo sa... | 85 | 8.4 | 33.1 | 27 | 42 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc. | 235 | Q14155 | 803 | ARHG7_HUMAN Rho guanine nucleotide exchange f... | 63 | 0.7 | 36.6 | 30 | 52 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 236 | Q92796 | 817 | DLG3_HUMAN Disks large homolog 3 OS=Homo sapi... | 42 | 0.72 | 36.6 | 43 | 62 | GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0019902; F:phosphatase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 237 | Q555L8 | 389 | Y4695_DICDI SH3 and FCH domain-containing pro... | 69 | 0.72 | 36.2 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 238 | Q9QY53 | 687 | NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M... | 53 | 0.73 | 36.6 | 34 | 57 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB. | 239 | Q8I190 | 369 | SH3G3_DROVI Endophilin-A OS=Drosophila virili... | 73 | 0.78 | 36.2 | 27 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 240 | Q92882 | 214 | OSTF1_HUMAN Osteoclast-stimulating factor 1 O... | 52 | 0.8 | 35.8 | 35 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 241 | O55043 | 646 | ARHG7_RAT Rho guanine nucleotide exchange fac... | 40 | 0.81 | 36.6 | 38 | 63 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD. |