| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q7RZU4 | 954 | SET2_NEUCR Histone-lysine N-methyltransferase... | 856 | 0 | 824 | 52 | 66 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q2H988 | 894 | SET2_CHAGB Histone-lysine N-methyltransferase... | 851 | 0 | 816 | 51 | 67 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q4IB50 | 1051 | SET2_GIBZE Histone-lysine N-methyltransferase... | 940 | 0 | 776 | 48 | 64 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q1DU03 | 1003 | SET2_COCIM Histone-lysine N-methyltransferase... | 813 | 0 | 706 | 47 | 62 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q2UTN6 | 965 | SET2_ASPOR Histone-lysine N-methyltransferase... | 781 | 0 | 695 | 49 | 63 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q4WTT2 | 966 | SET2_ASPFU Histone-lysine N-methyltransferase... | 770 | 0 | 681 | 49 | 63 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q5ASA5 | 980 | SET2_EMENI Histone-lysine N-methyltransferase... | 776 | 0 | 667 | 48 | 62 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q6BM04 | 731 | SET2_DEBHA Histone-lysine N-methyltransferase... | 95 | 1.2 | 36.6 | 26 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | O14026 | 798 | SET2_SCHPO Histone-lysine N-methyltransferase... | 419 | 2e-130 | 419 | 48 | 64 | GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:PomBase. | | | | | | | | | | GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:PomBase. | 10 | Q6CXP5 | 702 | SET2_KLULA Histone-lysine N-methyltransferase... | 424 | 2e-124 | 400 | 47 | 65 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q6FX50 | 716 | SET2_CANGA Histone-lysine N-methyltransferase... | 446 | 1e-119 | 388 | 44 | 63 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q6C5G5 | 768 | SET2_YARLI Histone-lysine N-methyltransferase... | 546 | 5e-116 | 380 | 40 | 54 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q757Y8 | 684 | SET2_ASHGO Histone-lysine N-methyltransferase... | 689 | 4e-114 | 372 | 36 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | P46995 | 733 | SET2_YEAST Histone-lysine N-methyltransferase... | 461 | 5e-114 | 373 | 42 | 61 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IPI:SGD. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:SGD. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:SGD.::GO:0016575; P:histone deacetylation; IMP:SGD.::GO:0060195; P:negative regulation of antisense RNA transcription; IMP:SGD.::GO:0071441; P:negative regulation of histone H3-K14 acetylation; IMP:SGD.::GO:2000616; P:negative regulation of histone H3-K9 acetylation; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0035066; P:positive regulation of histone acetylation; IGI:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006354; P:transcription elongation, DNA-dependent; IDA:SGD. | 15 | Q59XV0 | 844 | SET2_CANAL Histone-lysine N-methyltransferase... | 109 | 3.1 | 35.4 | 24 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | P0CO29 | 834 | SET2_CRYNB Histone-lysine N-methyltransferase... | 499 | 5e-108 | 360 | 41 | 57 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | P0CO28 | 834 | SET2_CRYNJ Histone-lysine N-methyltransferase... | 499 | 6e-108 | 360 | 41 | 57 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q4PBL3 | 972 | SET2_USTMA Histone-lysine N-methyltransferase... | 493 | 4e-88 | 308 | 35 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q9BYW2 | 2564 | SETD2_HUMAN Histone-lysine N-methyltransferas... | 387 | 1e-57 | 221 | 34 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q2LAE1 | 1759 | ASHH2_ARATH Histone-lysine N-methyltransferas... | 200 | 7e-48 | 189 | 44 | 64 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048653; P:anther development; IMP:TAIR.::GO:0016116; P:carotenoid metabolic process; IMP:TAIR.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0010452; P:histone H3-K36 methylation; IDA:TAIR.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0048481; P:ovule development; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0031062; P:positive regulation of histone methylation; IDA:TAIR.::GO:0040029; P:regulation of gene expression, epigenetic; IMP:TAIR.::GO:0010363; P:regulation of plant-type hypersensitive response; IMP:TAIR.::GO:0010223; P:secondary shoot formation; IMP:TAIR. | 21 | Q9VYD1 | 2313 | C1716_DROME Probable histone-lysine N-methylt... | 118 | 0.33 | 38.5 | 25 | 45 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:FlyBase.::GO:0051219; F:phosphoprotein binding; IPI:FlyBase. | | | | | | | | | | GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase. | 22 | Q6P2L6 | 1439 | NSD3_MOUSE Histone-lysine N-methyltransferase... | 225 | 1e-44 | 179 | 40 | 59 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q84WW6 | 492 | ASHH1_ARATH Histone-lysine N-methyltransferas... | 196 | 5e-44 | 171 | 43 | 60 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006281; P:DNA repair; IMP:TAIR.::GO:0010224; P:response to UV-B; IEP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR. | 24 | Q9BZ95 | 1437 | NSD3_HUMAN Histone-lysine N-methyltransferase... | 178 | 7e-44 | 177 | 45 | 63 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | O88491 | 2588 | NSD1_MOUSE Histone-lysine N-methyltransferase... | 178 | 1e-42 | 173 | 44 | 60 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | O96028 | 1365 | NSD2_HUMAN Probable histone-lysine N-methyltr... | 186 | 2e-42 | 172 | 44 | 59 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q96L73 | 2696 | NSD1_HUMAN Histone-lysine N-methyltransferase... | 178 | 2e-42 | 172 | 44 | 59 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q8BVE8 | 1365 | NSD2_MOUSE Probable histone-lysine N-methyltr... | 183 | 6e-42 | 171 | 44 | 60 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0003289; P:atrial septum primum morphogenesis; IMP:MGI.::GO:0003290; P:atrial septum secundum morphogenesis; IMP:MGI.::GO:0060348; P:bone development; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q99MY8 | 2958 | ASH1L_MOUSE Histone-lysine N-methyltransferas... | 216 | 1e-37 | 157 | 37 | 56 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | Q9NR48 | 2969 | ASH1L_HUMAN Histone-lysine N-methyltransferas... | 208 | 2e-37 | 156 | 37 | 57 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005923; C:tight junction; TAS:ProtInc. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006323; P:DNA packaging; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 31 | Q8MT36 | 1427 | MES4_DROME Probable histone-lysine N-methyltr... | 185 | 3e-35 | 149 | 38 | 56 | GO:0000228; C:nuclear chromosome; ISS:UniProtKB. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016458; P:gene silencing; ISS:UniProtKB.::GO:0018992; P:germ-line sex determination; ISS:UniProtKB. |
