| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8MT36 | 1427 | MES4_DROME Probable histone-lysine N-methyltr... | 185 | 3e-35 | 149 | 38 | 56 | GO:0000228; C:nuclear chromosome; ISS:UniProtKB. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016458; P:gene silencing; ISS:UniProtKB.::GO:0018992; P:germ-line sex determination; ISS:UniProtKB. | 32 | Q949T8 | 497 | ASHR3_ARATH Histone-lysine N-methyltransferas... | 176 | 5e-34 | 141 | 40 | 60 | GO:0000785; C:chromatin; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 33 | Q9VW15 | 2226 | ASH1_DROME Histone-lysine N-methyltransferase... | 276 | 1e-33 | 144 | 33 | 50 | GO:0005634; C:nucleus; IC:FlyBase.::GO:0035327; C:transcriptionally active chromatin; IMP:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); NAS:FlyBase.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); NAS:FlyBase.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0018991; P:oviposition; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | Q9M1X9 | 352 | ASHH4_ARATH Putative histone-lysine N-methylt... | 165 | 8e-31 | 129 | 38 | 59 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 35 | Q945S8 | 363 | ASHH3_ARATH Histone-lysine N-methyltransferas... | 152 | 3e-30 | 128 | 41 | 61 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 36 | Q1DR06 | 1271 | SET1_COCIM Histone-lysine N-methyltransferase... | 151 | 1e-19 | 98.6 | 33 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 37 | Q2UMH3 | 1229 | SET1_ASPOR Histone-lysine N-methyltransferase... | 151 | 1e-19 | 98.6 | 33 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 38 | Q5B0Y5 | 1220 | SET1_EMENI Histone-lysine N-methyltransferase... | 151 | 2e-19 | 98.2 | 32 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 39 | Q8IRW8 | 2431 | TRR_DROME Histone-lysine N-methyltransferase ... | 147 | 3e-19 | 97.8 | 36 | 54 | GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:FlyBase.::GO:0005102; F:receptor binding; IPI:FlyBase.::GO:0003713; F:transcription coactivator activity; IGI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:FlyBase.::GO:0007458; P:progression of morphogenetic furrow involved in compound eye morphogenesis; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 40 | Q4WNH8 | 1241 | SET1_ASPFU Histone-lysine N-methyltransferase... | 162 | 3e-19 | 97.4 | 33 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 41 | Q8X0S9 | 1313 | SET1_NEUCR Histone-lysine N-methyltransferase... | 169 | 4e-19 | 97.4 | 31 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 42 | Q28CQ7 | 406 | SUV92_XENTR Histone-lysine N-methyltransferas... | 237 | 5e-19 | 94 | 30 | 49 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | Q98SM3 | 748 | EZH2A_XENLA Histone-lysine N-methyltransferas... | 128 | 1e-18 | 94.7 | 38 | 56 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | P42124 | 760 | EZ_DROME Histone-lysine N-methyltransferase E... | 171 | 1e-18 | 94.7 | 35 | 50 | GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0000790; C:nuclear chromatin; NAS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006723; P:cuticle hydrocarbon biosynthetic process; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0016458; P:gene silencing; NAS:UniProtKB.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 45 | P38827 | 1080 | SET1_YEAST Histone-lysine N-methyltransferase... | 184 | 2e-18 | 94.4 | 30 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IMP:SGD. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:SGD.::GO:0000183; P:chromatin silencing at rDNA; TAS:SGD.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IDA:SGD.::GO:0018027; P:peptidyl-lysine dimethylation; IMP:SGD.::GO:0035066; P:positive regulation of histone acetylation; IGI:SGD.::GO:0043618; P:regulation of transcription from RNA polymerase II promoter in response to stress; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 46 | Q2GWF3 | 1076 | SET1_CHAGB Histone-lysine N-methyltransferase... | 151 | 3e-18 | 94 | 33 | 50 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 47 | Q18221 | 1507 | SET2_CAEEL Probable histone-lysine N-methyltr... | 148 | 3e-18 | 94.4 | 30 | 50 | GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 48 | Q9Y7R4 | 920 | SET1_SCHPO Histone-lysine N-methyltransferase... | 127 | 4e-18 | 93.6 | 40 | 53 | GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0000790; C:nuclear chromatin; NAS:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); TAS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0000077; P:DNA damage checkpoint; IGI:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 49 | Q4R381 | 746 | EZH2_MACFA Histone-lysine N-methyltransferase... | 128 | 6e-18 | 92.8 | 38 | 55 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 50 | Q15910 | 746 | EZH2_HUMAN Histone-lysine N-methyltransferase... | 128 | 6e-18 | 92.8 | 38 | 55 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q28D84 | 748 | EZH2_XENTR Histone-lysine N-methyltransferase... | 128 | 6e-18 | 92.8 | 38 | 55 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | Q6DGD3 | 411 | SV91A_DANRE Histone-lysine N-methyltransferas... | 141 | 6e-18 | 90.9 | 38 | 55 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031017; P:exocrine pancreas development; IMP:ZFIN.::GO:0051567; P:histone H3-K9 methylation; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 53 | Q61188 | 746 | EZH2_MOUSE Histone-lysine N-methyltransferase... | 128 | 6e-18 | 92.8 | 38 | 55 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0045120; C:pronucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001047; F:core promoter binding; IDA:MGI.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI. | | | | | | | | | | GO:0021695; P:cerebellar cortex development; IMP:MGI.::GO:0070314; P:G1 to G0 transition; IMP:MGI.::GO:0070734; P:histone H3-K27 methylation; IMP:MGI.::GO:0045605; P:negative regulation of epidermal cell differentiation; IMP:MGI.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0051154; P:negative regulation of striated muscle cell differentiation; IDA:MGI.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0014013; P:regulation of gliogenesis; IMP:MGI.::GO:0001932; P:regulation of protein phosphorylation; IMP:MGI.::GO:0000084; P:S phase of mitotic cell cycle; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 54 | A7E2Z2 | 747 | EZH1_BOVIN Histone-lysine N-methyltransferase... | 129 | 6e-18 | 92.4 | 40 | 58 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 55 | P70351 | 747 | EZH1_MOUSE Histone-lysine N-methyltransferase... | 129 | 7e-18 | 92.4 | 40 | 58 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 56 | Q4V863 | 748 | EZH2B_XENLA Histone-lysine N-methyltransferas... | 128 | 8e-18 | 92.4 | 38 | 55 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 57 | Q92800 | 747 | EZH1_HUMAN Histone-lysine N-methyltransferase... | 129 | 8e-18 | 92.4 | 40 | 58 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; TAS:ProtInc.::GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 58 | Q08BS4 | 760 | EZH2_DANRE Histone-lysine N-methyltransferase... | 128 | 9e-18 | 92 | 38 | 55 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 59 | Q75D88 | 975 | SET1_ASHGO Histone-lysine N-methyltransferase... | 151 | 9e-18 | 92.4 | 33 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 60 | O44757 | 1312 | LIN59_CAEEL Probable histone-lysine N-methylt... | 197 | 1e-17 | 92.4 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007413; P:axonal fasciculation; IMP:WormBase.::GO:0016358; P:dendrite development; IMP:WormBase.::GO:0001715; P:ectodermal cell fate specification; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0048566; P:embryonic digestive tract development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0040014; P:regulation of multicellular organism growth; IMP:WormBase.::GO:0045138; P:tail tip morphogenesis; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 61 | Q80UJ9 | 309 | SETMR_MOUSE Histone-lysine N-methyltransferas... | 216 | 2e-17 | 88.6 | 31 | 46 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
