rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P0C2N5 | 883 | SV421_RAT Histone-lysine N-methyltransferase ... | 55 | 0.11 | 40 | 36 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 182 | Q4FZB7 | 885 | SV421_HUMAN Histone-lysine N-methyltransferas... | 55 | 0.11 | 40 | 36 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 183 | Q6GP17 | 855 | S421A_XENLA Histone-lysine N-methyltransferas... | 55 | 0.14 | 39.7 | 36 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 184 | Q14203 | 1278 | DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapien... | 219 | 0.16 | 39.7 | 26 | 43 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; NAS:ProtInc.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 185 | Q5RJX8 | 785 | S421B_XENLA Histone-lysine N-methyltransferas... | 55 | 0.16 | 39.7 | 36 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 186 | Q5AZY3 | 641 | SET9_EMENI Histone-lysine N-methyltransferase... | 57 | 0.19 | 39.3 | 33 | 46 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 187 | Q06ZW3 | 551 | SETB2_DANRE Histone-lysine N-methyltransferas... | 64 | 0.2 | 38.9 | 36 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0001947; P:heart looping; IMP:UniProtKB.::GO:0070986; P:left/right axis specification; IMP:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB. | 188 | Q54DL6 | 521 | Y2140_DICDI SET and MYND domain-containing pr... | 41 | 0.21 | 38.9 | 41 | 63 | | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 189 | O08788 | 1281 | DCTN1_MOUSE Dynactin subunit 1 OS=Mus musculu... | 130 | 0.22 | 39.3 | 29 | 50 | GO:0031252; C:cell leading edge; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 190 | Q9USK2 | 441 | SET9_SCHPO Histone-lysine N-methyltransferase... | 69 | 0.23 | 38.9 | 33 | 45 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IMP:PomBase. | | | | | | | | | | GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0000077; P:DNA damage checkpoint; IMP:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 191 | Q5U3H2 | 808 | SV421_DANRE Histone-lysine N-methyltransferas... | 55 | 0.36 | 38.5 | 35 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 192 | Q29RP8 | 393 | SV421_BOVIN Histone-lysine N-methyltransferas... | 55 | 0.52 | 37.4 | 36 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 193 | Q6FTT0 | 515 | SET5_CANGA Potential protein lysine methyltra... | 95 | 0.62 | 37.4 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 194 | A0JMZ4 | 761 | SV422_XENLA Histone-lysine N-methyltransferas... | 55 | 0.68 | 37.4 | 35 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 195 | Q9T0G7 | 650 | SUVH9_ARATH Probable histone-lysine N-methylt... | 180 | 0.7 | 37.4 | 24 | 40 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009294; P:DNA mediated transformation; IMP:TAIR. | 196 | Q5VQL1 | 708 | RH14_ORYSJ DEAD-box ATP-dependent RNA helicas... | 57 | 0.99 | 37 | 39 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. | 197 | O95402 | 600 | MED26_HUMAN Mediator of RNA polymerase II tra... | 55 | 1.2 | 36.6 | 35 | 64 | GO:0016592; C:mediator complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc. | | | | | | | | | | GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome. | 198 | O74467 | 319 | SET5_SCHPO SET domain-containing protein 5 OS... | 97 | 1.5 | 35.8 | 34 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; TAS:PomBase. | | | | | | | | | | | 199 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 120 | 1.9 | 36.2 | 27 | 40 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 200 | Q6C519 | 866 | SET9_YARLI Histone-lysine N-methyltransferase... | 69 | 2 | 35.8 | 30 | 43 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 201 | Q9CWR2 | 428 | SMYD3_MOUSE SET and MYND domain-containing pr... | 106 | 2.6 | 35.4 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 202 | A5DQN2 | 483 | SET5_PICGU Potential protein lysine methyltra... | 39 | 3 | 35 | 46 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 203 | Q9W5E0 | 1300 | SUV42_DROME Histone-lysine N-methyltransferas... | 88 | 4.1 | 35 | 27 | 43 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:FlyBase. | | | | | | | | | | GO:0034772; P:histone H4-K20 dimethylation; IMP:FlyBase.::GO:0034773; P:histone H4-K20 trimethylation; IMP:FlyBase.::GO:0040029; P:regulation of gene expression, epigenetic; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 204 | A5PK23 | 599 | MED26_BOVIN Mediator of RNA polymerase II tra... | 55 | 4.2 | 34.7 | 35 | 64 | GO:0016592; C:mediator complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0001104; F:RNA polymerase II transcription cofactor activity; ISS:UniProtKB. | | | | | | | | | | | 205 | P42948 | 560 | SET4_YEAST SET domain-containing protein 4 OS... | 147 | 4.9 | 34.7 | 23 | 48 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW. | 206 | P28774 | 1004 | AT1B_ARTSF Sodium/potassium-transporting ATPa... | 97 | 5 | 34.7 | 24 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:EC. | | | | | | | | | | GO:0006754; P:ATP biosynthetic process; IEA:InterPro. | 207 | Q86Y97 | 462 | SV422_HUMAN Histone-lysine N-methyltransferas... | 55 | 5.7 | 34.3 | 33 | 47 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 208 | Q7TN02 | 588 | MED26_MOUSE Mediator of RNA polymerase II tra... | 55 | 6 | 34.3 | 31 | 64 | GO:0016592; C:mediator complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0001104; F:RNA polymerase II transcription cofactor activity; ISS:UniProtKB. | | | | | | | | | | | 209 | Q5S006 | 2527 | LRRK2_MOUSE Leucine-rich repeat serine/threon... | 88 | 6.7 | 34.3 | 27 | 45 | GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0005802; C:trans-Golgi network; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0035564; P:regulation of kidney size; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 210 | Q6DHG0 | 373 | SETD7_DANRE Histone-lysine N-methyltransferas... | 54 | 6.8 | 33.9 | 39 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 211 | Q5NFN4 | 668 | UVRB_FRATT UvrABC system protein B OS=Francis... | 70 | 7.2 | 34.3 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:InterPro. | | | | | | | | | | GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW. |