| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q4KLN7 | 525 | ARFG3_RAT ADP-ribosylation factor GTPase-acti... | 48 | 0.0000001 | 59.3 | 52 | 65 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 92 | Q4R4C9 | 516 | ARFG3_MACFA ADP-ribosylation factor GTPase-ac... | 48 | 0.0000002 | 58.9 | 52 | 65 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 93 | Q5R787 | 516 | ARFG3_PONAB ADP-ribosylation factor GTPase-ac... | 48 | 0.0000002 | 58.5 | 52 | 65 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 94 | Q9NP61 | 516 | ARFG3_HUMAN ADP-ribosylation factor GTPase-ac... | 48 | 0.0000002 | 58.5 | 52 | 65 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0008565; F:protein transporter activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0009306; P:protein secretion; IEP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB. | 95 | Q09531 | 529 | YQP4_CAEEL Uncharacterized protein F07F6.4 OS... | 75 | 0.0000003 | 58.2 | 36 | 56 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 96 | O94601 | 321 | YC8E_SCHPO Uncharacterized protein C622.14 OS... | 66 | 0.0000006 | 56.6 | 41 | 61 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; ISS:PomBase. | 97 | Q1ZXH8 | 1632 | GXCDD_DICDI Guanine exchange factor for Rac 3... | 100 | 0.000001 | 56.6 | 34 | 58 | GO:0005938; C:cell cortex; IMP:dictyBase.::GO:0032009; C:early phagosome; IMP:dictyBase.::GO:0005626; C:insoluble fraction; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:dictyBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:dictyBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IPI:dictyBase. | 98 | Q8RXE7 | 649 | AGD14_ARATH Probable ADP-ribosylation factor ... | 125 | 0.0002 | 49.7 | 29 | 50 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 99 | Q54DK4 | 1352 | AK1_DICDI Alpha-protein kinase 1 OS=Dictyoste... | 124 | 0.0002 | 49.7 | 29 | 48 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 100 | P40956 | 396 | GTS1_YEAST Protein GTS1 OS=Saccharomyces cere... | 106 | 0.0002 | 48.9 | 28 | 49 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IMP:SGD.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0000989; F:transcription factor binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:SGD.::GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007624; P:ultradian rhythm; IMP:SGD. | 101 | O13818 | 1213 | YEE2_SCHPO Uncharacterized PH domain-containi... | 137 | 0.0002 | 49.3 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 102 | Q7YQL5 | 802 | OPHN1_PONPY Oligophrenin-1 OS=Pongo pygmaeus ... | 279 | 0.0005 | 48.1 | 23 | 39 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 103 | Q7YQL6 | 802 | OPHN1_PANTR Oligophrenin-1 OS=Pan troglodytes... | 279 | 0.0005 | 48.1 | 23 | 39 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 104 | O60890 | 802 | OPHN1_HUMAN Oligophrenin-1 OS=Homo sapiens (H... | 279 | 0.0005 | 47.8 | 23 | 39 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:ProtInc.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc. | 105 | P32572 | 300 | SPS18_YEAST Sporulation protein SPS18 OS=Sacc... | 73 | 0.001 | 46.2 | 33 | 60 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:SGD. | 106 | P0CAX5 | 802 | OPHN1_RAT Oligophrenin-1 OS=Rattus norvegicus... | 267 | 0.001 | 47 | 22 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 107 | Q99J31 | 802 | OPHN1_MOUSE Oligophrenin-1 OS=Mus musculus (M... | 176 | 0.002 | 46.2 | 25 | 46 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IMP:MGI.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI. | 108 | Q8WWN9 | 437 | ICEF1_HUMAN Interactor protein for cytohesin ... | 103 | 0.004 | 44.7 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005344; F:oxygen transporter activity; NAS:UniProtKB.::GO:0004601; F:peroxidase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006979; P:response to oxidative stress; ISS:UniProtKB. | 109 | Q4KLH5 | 561 | AGFG1_RAT Arf-GAP domain and FG repeat-contai... | 128 | 0.009 | 43.5 | 29 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 110 | Q8K2K6 | 561 | AGFG1_MOUSE Arf-GAP domain and FG repeat-cont... | 128 | 0.01 | 43.5 | 29 | 45 | GO:0042995; C:cell projection; IDA:MGI.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0045109; P:intermediate filament organization; IMP:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007289; P:spermatid nucleus differentiation; IMP:MGI.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 111 | P52594 | 562 | AGFG1_HUMAN Arf-GAP domain and FG repeat-cont... | 119 | 0.01 | 43.5 | 29 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 112 | Q2TA45 | 562 | AGFG1_BOVIN Arf-GAP domain and FG repeat-cont... | 119 | 0.01 | 43.5 | 29 | 45 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 113 | Q5DU31 | 406 | ICEF1_MOUSE Interactor protein for cytohesin ... | 102 | 0.018 | 42.4 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 114 | Q8K3H0 | 707 | DP13A_MOUSE DCC-interacting protein 13-alpha ... | 100 | 0.019 | 42.7 | 30 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB. | 115 | Q9UKG1 | 709 | DP13A_HUMAN DCC-interacting protein 13-alpha ... | 100 | 0.022 | 42.7 | 30 | 48 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0012506; C:vesicle membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0043422; F:protein kinase B binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:BHF-UCL.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0090003; P:regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046324; P:regulation of glucose import; IMP:BHF-UCL. | 116 | Q80VL0 | 406 | ICEF1_RAT Interactor protein for cytohesin ex... | 103 | 0.059 | 40.8 | 28 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0033126; P:positive regulation of GTP catabolic process; IDA:RGD. | 117 | A6NI28 | 874 | RHG42_HUMAN Rho GTPase-activating protein 42 ... | 246 | 0.068 | 41.2 | 21 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 118 | Q80YA9 | 1032 | CNKR2_MOUSE Connector enhancer of kinase supp... | 101 | 0.086 | 40.8 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 119 | Q8WXI2 | 1034 | CNKR2_HUMAN Connector enhancer of kinase supp... | 101 | 0.087 | 40.8 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 120 | Q9Z1T4 | 1032 | CNKR2_RAT Connector enhancer of kinase suppre... | 101 | 0.088 | 40.8 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 121 | Q9UQC2 | 676 | GAB2_HUMAN GRB2-associated-binding protein 2 ... | 97 | 0.095 | 40.4 | 28 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB. |
