Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Magnaporthe oryzae 70-15 (MG8)
Locus:
MGG_01597
Length:
1126
Number of sequences:
12991
Description:
ARF GTPase activator
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q9UQC2    676   GAB2_HUMAN GRB2-associated-binding protein 2 ...970.095     40.4     28     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; IDA:UniProtKB.
GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.
122Q5KSL6    1271   DGKK_HUMAN Diacylglycerol kinase kappa OS=Hom...1050.13     40     31     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; IDA:HGNC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; IEA:InterPro.::GO:0046339; P:diacylglycerol metabolic process; IDA:HGNC.::GO:0035556; P:intracellular signal transduction; IDA:HGNC.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0006979; P:response to oxidative stress; IDA:HGNC.
123Q9QYY0    695   GAB1_MOUSE GRB2-associated-binding protein 1 ...990.17     39.7     28     43GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IDA:MGI.
GO:0007257; P:activation of JUN kinase activity; IMP:MGI.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:MGI.::GO:0008544; P:epidermis development; IMP:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0070102; P:interleukin-6-mediated signaling pathway; IMP:MGI.::GO:0060711; P:labyrinthine layer development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0030334; P:regulation of cell migration; IGI:MGI.::GO:0006979; P:response to oxidative stress; IDA:MGI.
124Q99PF6    694   GAB1_MESAU GRB2-associated-binding protein 1 ...990.17     39.7     28     43
GO:0005543; F:phospholipid binding; IEA:InterPro.
125Q8NEU8    664   DP13B_HUMAN DCC-interacting protein 13-beta O...490.21     39.3     39     55GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
126Q9Z1S8    665   GAB2_MOUSE GRB2-associated-binding protein 2 ...970.25     39.3     27     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:UniProtKB.
GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IMP:UniProtKB.
127Q9UNA1    814   RHG26_HUMAN Rho GTPase-activating protein 26 ...1770.32     38.9     22     44GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
128Q8IVF5    1701   TIAM2_HUMAN T-lymphoma invasion and metastasi...1190.32     38.9     29     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
129Q9XWN6    709   ANI3_CAEEL Anillin-like protein 3 OS=Caenorha...950.32     38.9     25     48
GO:0005543; F:phospholipid binding; IEA:InterPro.
130Q6ZQ82    814   RHG26_MOUSE Rho GTPase-activating protein 26 ...1770.4     38.5     22     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
131Q9EQH1    665   GAB2_RAT GRB2-associated-binding protein 2 OS...970.46     38.1     27     41GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:UniProtKB.
GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.
132Q8K3G9    662   DP13B_MOUSE DCC-interacting protein 13-beta O...490.53     38.1     37     55GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB.
133Q6ZM89    805   RHG42_DANRE Rho GTPase-activating protein 42 ...2490.62     37.7     21     39GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
134Q9W5D0    1820   Y34F_DROME Uncharacterized protein CG42248 OS...830.67     37.7     33     46GO:0005856; C:cytoskeleton; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.
135Q13480    694   GAB1_HUMAN GRB2-associated-binding protein 1 ...990.68     37.7     27     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
136A6QLU3    694   GAB1_BOVIN GRB2-associated-binding protein 1 ...990.72     37.7     27     43
GO:0005543; F:phospholipid binding; IEA:InterPro.
137Q9HB21    404   PKHA1_HUMAN Pleckstrin homology domain-contai...960.92     37     25     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0045184; P:establishment of protein localization; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IDA:UniProtKB.::GO:0031529; P:ruffle organization; IDA:UniProtKB.
138P45443    4367   DYHC_NEUCR Dynein heavy chain, cytoplasmic OS...571.1     37.4     39     53GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
139Q54XE8    576   GACP_DICDI Rho GTPase-activating protein gacP...2391.5     36.6     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
140Q64398    1154   DGKH_MESAU Diacylglycerol kinase eta OS=Mesoc...771.6     36.6     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
141Q8BUL6    383   PKHA1_MOUSE Pleckstrin homology domain-contai...961.7     36.2     25     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008209; P:androgen metabolic process; IMP:MGI.::GO:0008210; P:estrogen metabolic process; IGI:MGI.::GO:0060325; P:face morphogenesis; IMP:MGI.::GO:0033327; P:Leydig cell differentiation; IMP:MGI.::GO:0001553; P:luteinization; IGI:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.
142Q5FWH7    689   S39AC_MOUSE Zinc transporter ZIP12 OS=Mus mus...1561.8     36.2     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
143Q86XP1    1220   DGKH_HUMAN Diacylglycerol kinase eta OS=Homo ...802.7     35.8     31     49GO:0005768; C:endosome; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; IMP:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051259; P:protein oligomerization; IMP:UniProtKB.
144Q7TQG1    1173   PKHA6_MOUSE Pleckstrin homology domain-contai...1052.8     35.8     27     45
GO:0005543; F:phospholipid binding; IEA:InterPro.
145Q6ZPF3    1715   TIAM2_MOUSE T-lymphoma invasion and metastasi...1174.7     35     24     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
146Q180E4    787   LON_CLOD6 Lon protease OS=Clostridium diffici...1785     35     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
147Q6DFV3    1944   RHG21_MOUSE Rho GTPase-activating protein 21 ...1167.2     34.7     24     41GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
148Q09994    1009   ANI2_CAEEL Anillin-like protein 2 OS=Caenorha...1057.7     34.3     28     46GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.
149Q8BSM5    595   GAB3_MOUSE GRB2-associated-binding protein 3 ...1498.7     33.9     26     41
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030225; P:macrophage differentiation; IDA:MGI.
150B6RSP1    1197   PKHA7_DANRE Pleckstrin homology domain-contai...809.3     34.3     26     48GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB.
GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB.
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