| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A1D9Z6 | 1388 | DCL2_NEOFI Dicer-like protein 2 OS=181) (Aspe... | 579 | 2e-26 | 122 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 32 | A2QX45 | 1362 | DCL22_ASPNC Dicer-like protein 2-2 OS=Aspergi... | 354 | 0.0000000000009 | 77.4 | 23 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 33 | Q4WA22 | 1388 | DCL2_ASPFU Dicer-like protein 2 OS=A1100) (As... | 136 | 0.002 | 47 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 34 | A1C9M6 | 1389 | DCL2_ASPCL Dicer-like protein 2 OS=3887 / NRR... | 563 | 3e-26 | 121 | 27 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 35 | Q9LXW7 | 1580 | DCL3_ARATH Endoribonuclease Dicer homolog 3 O... | 180 | 7.8 | 35 | 24 | 39 | GO:0005730; C:nucleolus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010216; P:maintenance of DNA methylation; IMP:TAIR.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IMP:TAIR. | 36 | P0C5H7 | 1429 | DCL2_EMENI Dicer-like protein 2 OS=194 / M139... | 34 | 0.57 | 38.5 | 44 | 65 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 37 | Q6TV19 | 1865 | DICER_DANRE Endoribonuclease Dicer OS=Danio r... | 100 | 0.97 | 38.1 | 30 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070883; F:pre-miRNA binding; IDA:ZFIN.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0035279; P:mRNA cleavage involved in gene silencing by miRNA; IGI:ZFIN.::GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB.::GO:0021591; P:ventricular system development; IMP:ZFIN. | 38 | Q7SCC1 | 1540 | DCL2_NEUCR Dicer-like protein 2 OS=1257 / FGS... | 488 | 0.0000000000001 | 80.1 | 24 | 38 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro. | 39 | Q99J87 | 678 | DHX58_MOUSE Probable ATP-dependent RNA helica... | 532 | 1e-29 | 130 | 28 | 44 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IMP:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IMP:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; IMP:UniProtKB. | 40 | Q6TUI4 | 1923 | DICER_BOVIN Endoribonuclease Dicer OS=Bos tau... | 388 | 5e-20 | 101 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB. | 41 | B3DLA6 | 1893 | DICER_XENTR Endoribonuclease Dicer OS=Xenopus... | 382 | 8e-20 | 100 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB. | 42 | A0MQH0 | 1917 | DICER_CRIGR Endoribonuclease Dicer OS=Cricetu... | 110 | 0.85 | 38.1 | 29 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB. | 43 | Q25BN1 | 1921 | DICER_CHICK Endoribonuclease Dicer OS=Gallus ... | 76 | 1.9 | 37 | 34 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro. | | | | | | | | | | GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB. | 44 | Q9UPY3 | 1922 | DICER_HUMAN Endoribonuclease Dicer OS=Homo sa... | 76 | 1.8 | 37 | 34 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016442; C:RNA-induced silencing complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004525; F:ribonuclease III activity; IDA:UniProtKB. | | | | | | | | | | GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0021675; P:nerve development; ISS:BHF-UCL.::GO:0048812; P:neuron projection morphogenesis; ISS:BHF-UCL.::GO:0032290; P:peripheral nervous system myelin formation; ISS:BHF-UCL.::GO:0031643; P:positive regulation of myelination; ISS:BHF-UCL.::GO:0014040; P:positive regulation of Schwann cell differentiation; ISS:BHF-UCL.::GO:0031054; P:pre-miRNA processing; IDA:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; IDA:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; IMP:UniProtKB. | 45 | Q8R418 | 1916 | DICER_MOUSE Endoribonuclease Dicer OS=Mus mus... | 110 | 0.18 | 40.4 | 29 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004525; F:ribonuclease III activity; ISS:UniProtKB. | | | | | | | | | | GO:0010626; P:negative regulation of Schwann cell proliferation; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0021675; P:nerve development; IMP:BHF-UCL.::GO:0048812; P:neuron projection morphogenesis; IMP:BHF-UCL.::GO:0032290; P:peripheral nervous system myelin formation; IMP:BHF-UCL.::GO:0031643; P:positive regulation of myelination; IMP:BHF-UCL.::GO:0014040; P:positive regulation of Schwann cell differentiation; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0008593; P:regulation of Notch signaling pathway; IC:BHF-UCL.::GO:0001932; P:regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB. | 46 | O95786 | 925 | DDX58_HUMAN Probable ATP-dependent RNA helica... | 512 | 7e-25 | 116 | 27 | 44 | GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0009597; P:detection of virus; IDA:BHF-UCL.::GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; IDA:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.::GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.::GO:0039529; P:RIG-I signaling pathway; IMP:UniProtKB. | 47 | Q6Q899 | 926 | DDX58_MOUSE Probable ATP-dependent RNA helica... | 510 | 1e-24 | 116 | 26 | 46 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0002230; P:positive regulation of defense response to virus by host; ISS:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0043330; P:response to exogenous dsRNA; IMP:MGI. | 48 | Q9GLV6 | 940 | DDX58_PIG Probable ATP-dependent RNA helicase... | 517 | 7e-24 | 113 | 27 | 43 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.::GO:0005923; C:tight junction; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0002230; P:positive regulation of defense response to virus by host; ISS:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0039529; P:RIG-I signaling pathway; ISS:UniProtKB. | 49 | Q7SDF3 | 1168 | MPH1_NEUCR ATP-dependent DNA helicase mph-1 O... | 538 | 1e-20 | 103 | 25 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 50 | Q9HE09 | 783 | MFH2_SCHPO Putative ATP-dependent RNA helicas... | 511 | 5e-19 | 97.4 | 26 | 41 | GO:0005730; C:nucleolus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IC:PomBase.::GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:PomBase.::GO:0033567; P:DNA replication, Okazaki fragment processing; ISS:PomBase. | 51 | A4RN08 | 1102 | MPH1_MAGO7 ATP-dependent DNA helicase MPH1 OS... | 550 | 8e-19 | 97.1 | 25 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 52 | Q2HG76 | 1134 | MPH1_CHAGB ATP-dependent DNA helicase MPH1 OS... | 537 | 2e-18 | 95.9 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 53 | Q96C10 | 678 | DHX58_HUMAN Probable ATP-dependent RNA helica... | 180 | 0.00000000003 | 72 | 33 | 49 | GO:0005737; C:cytoplasm; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IDA:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IDA:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; ISS:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; ISS:UniProtKB. | 54 | Q9VCU9 | 2249 | DCR1_DROME Endoribonuclease Dcr-1 OS=Drosophi... | 75 | 0.8 | 38.1 | 35 | 44 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016442; C:RNA-induced silencing complex; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016443; F:bidentate ribonuclease III activity; IDA:FlyBase.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0033227; P:dsRNA transport; IMP:FlyBase.::GO:0042078; P:germ-line stem cell division; IMP:FlyBase.::GO:0045448; P:mitotic cell cycle, embryonic; IMP:FlyBase.::GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0031054; P:pre-miRNA processing; IDA:FlyBase.::GO:0030422; P:production of siRNA involved in RNA interference; IDA:UniProtKB.::GO:0007367; P:segment polarity determination; IGI:FlyBase.::GO:0035087; P:siRNA loading onto RISC involved in RNA interference; IMP:FlyBase. | 55 | Q8Y691 | 229 | RNC_LISMO Ribonuclease 3 OS=Listeria monocyto... | 180 | 1e-16 | 85.9 | 33 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:EC.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0016075; P:rRNA catabolic process; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 56 | Q8R5F7 | 1025 | IFIH1_MOUSE Interferon-induced helicase C dom... | 232 | 0.00000000004 | 72 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0009615; P:response to virus; IMP:UniProtKB. | 57 | Q9UT23 | 834 | MFH1_SCHPO ATP-dependent DNA helicase mfh1 OS... | 507 | 1e-16 | 89.4 | 22 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0071821; C:FANCM-MHF complex; ISS:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IC:PomBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IDA:PomBase. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:PomBase.::GO:0033567; P:DNA replication, Okazaki fragment processing; ISS:PomBase.::GO:2000042; P:negative regulation of double-strand break repair via homologous recombination; IMP:PomBase.::GO:0071932; P:replication fork reversal; IDA:PomBase.::GO:0000732; P:strand displacement; IDA:PomBase. | 58 | Q58900 | 778 | Y1505_METJA Putative ATP-dependent RNA helica... | 485 | 2e-16 | 88.6 | 25 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:InterPro. | 59 | Q8IYD8 | 2048 | FANCM_HUMAN Fanconi anemia group M protein OS... | 562 | 4e-16 | 88.6 | 22 | 41 | GO:0071821; C:FANCM-MHF complex; IDA:UniProtKB.::GO:0043240; C:Fanconi anaemia nuclear complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006281; P:DNA repair; TAS:Reactome.::GO:0031297; P:replication fork processing; IMP:UniProtKB.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:UniProtKB. | 60 | Q9BYX4 | 1025 | IFIH1_HUMAN Interferon-induced helicase C dom... | 220 | 0.0000000003 | 68.9 | 30 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0039528; P:cytoplasmic pattern recognition receptor signaling pathway in response to virus; TAS:UniProtKB.::GO:0009597; P:detection of virus; TAS:BHF-UCL.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0032727; P:positive regulation of interferon-alpha production; IMP:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB. | 61 | Q92AK3 | 229 | RNC_LISIN Ribonuclease 3 OS=Listeria innocua ... | 180 | 5e-16 | 84 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:EC.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0016075; P:rRNA catabolic process; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. |
