rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q09778 | 899 | TSC1_SCHPO Tuberous sclerosis 1 protein homol... | 911 | 9e-33 | 140 | 22 | 41 | GO:0033596; C:TSC1-TSC2 complex; IPI:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0043091; P:L-arginine import; IGI:PomBase.::GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.::GO:0033157; P:regulation of intracellular protein transport; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 2 | Q92574 | 1164 | TSC1_HUMAN Hamartin OS=Homo sapiens (Human). ... | 239 | 0.00001 | 53.5 | 23 | 38 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0033596; C:TSC1-TSC2 complex; IDA:UniProtKB. | | | | | | | | | | GO:0051087; F:chaperone binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0007160; P:cell-matrix adhesion; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0017148; P:negative regulation of translation; IMP:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IDA:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:0043666; P:regulation of phosphoprotein phosphatase activity; IMP:UniProtKB.::GO:0051492; P:regulation of stress fiber assembly; IDA:UniProtKB.::GO:0006407; P:rRNA export from nucleus; IMP:UniProtKB. | 3 | Q9EP53 | 1161 | TSC1_MOUSE Hamartin OS=Mus musculus (Mouse). ... | 239 | 0.00003 | 51.6 | 23 | 38 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047485; F:protein N-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; IMP:MGI.::GO:0030030; P:cell projection organization; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0006813; P:potassium ion transport; IMP:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0050808; P:synapse organization; IMP:MGI. | 4 | Q9Z136 | 1163 | TSC1_RAT Hamartin OS=Rattus norvegicus (Rat).... | 239 | 0.00008 | 50.4 | 23 | 38 | GO:0030426; C:growth cone; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IPI:RGD.::GO:0030695; F:GTPase regulator activity; IMP:RGD.::GO:0047485; F:protein N-terminus binding; IPI:RGD. | | | | | | | | | | GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051492; P:regulation of stress fiber assembly; IMP:RGD. | 5 | Q5XKE5 | 535 | K2C79_HUMAN Keratin, type II cytoskeletal 79 ... | 191 | 0.0002 | 49.3 | 28 | 50 | GO:0045095; C:keratin filament; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | | 6 | Q148H7 | 535 | K2C79_BOVIN Keratin, type II cytoskeletal 79 ... | 197 | 0.003 | 44.7 | 28 | 47 | GO:0045095; C:keratin filament; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | | 7 | Q8VED5 | 531 | K2C79_MOUSE Keratin, type II cytoskeletal 79 ... | 154 | 0.01 | 43.1 | 28 | 48 | GO:0045095; C:keratin filament; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | | 8 | P22312 | 286 | PU92_SCICO Puff II/9-2 protein OS=Sciara copr... | 198 | 0.058 | 40.4 | 24 | 43 | | | | | | | | | | | | | | | | | | | | | | 9 | P11047 | 1609 | LAMC1_HUMAN Laminin subunit gamma-1 OS=Homo s... | 241 | 0.11 | 40.4 | 24 | 47 | GO:0005615; C:extracellular space; NAS:UniProtKB.::GO:0005606; C:laminin-1 complex; NAS:UniProtKB.::GO:0043259; C:laminin-10 complex; TAS:BHF-UCL.::GO:0043260; C:laminin-11 complex; TAS:BHF-UCL. | | | | | | | | | | GO:0005201; F:extracellular matrix structural constituent; IMP:HGNC. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016477; P:cell migration; IMP:HGNC.::GO:0007492; P:endoderm development; TAS:ProtInc.::GO:0022617; P:extracellular matrix disassembly; IMP:HGNC.::GO:0031581; P:hemidesmosome assembly; IMP:HGNC.::GO:0050679; P:positive regulation of epithelial cell proliferation; TAS:HGNC.::GO:0006461; P:protein complex assembly; IDA:HGNC.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL. | 10 | Q60902 | 907 | EP15R_MOUSE Epidermal growth factor receptor ... | 167 | 0.12 | 40 | 24 | 51 | GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 11 | Q0VF96 | 1302 | CGNL1_HUMAN Cingulin-like protein 1 OS=Homo s... | 281 | 0.15 | 39.7 | 27 | 46 | GO:0016459; C:myosin complex; IEA:InterPro.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 12 | P11657 | 1565 | PAC_STRMU Major cell-surface adhesin PAc OS=S... | 300 | 0.19 | 39.7 | 22 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009274; C:peptidoglycan-based cell wall; IEA:InterPro. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0044406; P:adhesion to host; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:InterPro. | 13 | Q9LI74 | 1004 | CHUP1_ARATH Protein CHUP1, chloroplastic OS=A... | 204 | 0.28 | 38.9 | 26 | 45 | GO:0009707; C:chloroplast outer membrane; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | GO:0009902; P:chloroplast relocation; IMP:TAIR. | 14 | Q6NZL0 | 945 | CF174_MOUSE Uncharacterized protein C6orf174 ... | 224 | 0.5 | 38.1 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 15 | Q2KJ21 | 680 | CACO1_BOVIN Calcium-binding and coiled-coil d... | 347 | 0.63 | 37.7 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 16 | Q6P864 | 429 | K1C18_XENTR Keratin, type I cytoskeletal 18 O... | 223 | 0.72 | 37.4 | 27 | 47 | GO:0005882; C:intermediate filament; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | | 17 | Q9Z2Y3 | 366 | HOME1_MOUSE Homer protein homolog 1 OS=Mus mu... | 172 | 0.81 | 37 | 27 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043034; C:costamere; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:MGI.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:MGI.::GO:0090279; P:regulation of calcium ion import; IMP:BHF-UCL.::GO:2001256; P:regulation of store-operated calcium entry; IMP:BHF-UCL.::GO:0003009; P:skeletal muscle contraction; IMP:MGI.::GO:0048741; P:skeletal muscle fiber development; IMP:MGI. | 18 | Q5JLY8 | 709 | GOGA5_ORYSJ Golgin-84 OS=Oryza sativa subsp. ... | 139 | 0.89 | 37 | 33 | 49 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 19 | Q9P219 | 2028 | DAPLE_HUMAN Protein Daple OS=Homo sapiens (Hu... | 177 | 0.89 | 37.4 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 20 | Q5TF21 | 947 | CF174_HUMAN Uncharacterized protein C6orf174 ... | 224 | 1.1 | 37 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 21 | Q9UBC2 | 864 | EP15R_HUMAN Epidermal growth factor receptor ... | 167 | 1.1 | 37 | 23 | 50 | GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 22 | P30622 | 1438 | CLIP1_HUMAN CAP-Gly domain-containing linker ... | 313 | 1.1 | 37 | 26 | 43 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; TAS:ProtInc.::GO:0005882; C:intermediate filament; TAS:ProtInc.::GO:0000776; C:kinetochore; TAS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 23 | Q7N291 | 415 | HUTI_PHOLL Imidazolonepropionase OS=Photorhab... | 71 | 1.2 | 36.6 | 32 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050480; F:imidazolonepropionase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019556; P:histidine catabolic process to glutamate and formamide; IEA:InterPro. | 24 | O95613 | 3336 | PCNT_HUMAN Pericentrin OS=Homo sapiens (Human... | 197 | 1.8 | 36.2 | 29 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042384; P:cilium assembly; IDA:MGI.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome. | 25 | P42566 | 896 | EPS15_HUMAN Epidermal growth factor receptor ... | 172 | 2.6 | 35.8 | 23 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0048268; P:clathrin coat assembly; IDA:BHF-UCL.::GO:0032456; P:endocytic recycling; IC:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 26 | Q5WHM8 | 876 | SYA_BACSK Alanine--tRNA ligase OS=Bacillus cl... | 92 | 2.7 | 35.4 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004813; F:alanine-tRNA ligase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro. | 27 | Q6VGS5 | 2009 | DAPLE_MOUSE Protein Daple OS=Mus musculus (Mo... | 306 | 3 | 35.4 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; IDA:UniProtKB. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0043621; F:protein self-association; IPI:UniProtKB. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 28 | Q6IG01 | 519 | K2C1B_RAT Keratin, type II cytoskeletal 1b OS... | 185 | 3.8 | 35 | 25 | 43 | GO:0045095; C:keratin filament; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | | 29 | A9II65 | 1176 | SMC_BORPD Chromosome partition protein Smc OS... | 123 | 4.2 | 35 | 29 | 46 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro. | 30 | P36583 | 1016 | PCK2_SCHPO Protein kinase C-like 2 OS=Schizos... | 181 | 5.2 | 34.7 | 26 | 45 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005622; C:intracellular; IC:GOC. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IC:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase. | 31 | B2KEW8 | 165 | ATPF_ELUMP ATP synthase subunit b OS=Elusimic... | 89 | 5.2 | 33.5 | 29 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW. | | | | | | | | | | GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. |