rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q5XIC8 | 295 | ALKB3_RAT Alpha-ketoglutarate-dependent dioxy... | 134 | 0.0000001 | 56.6 | 30 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; ISS:UniProtKB. | 2 | Q8K1E6 | 286 | ALKB3_MOUSE Alpha-ketoglutarate-dependent dio... | 134 | 0.0000005 | 54.7 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; IDA:MGI.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; ISS:UniProtKB. | 3 | Q96Q83 | 286 | ALKB3_HUMAN Alpha-ketoglutarate-dependent dio... | 134 | 0.000001 | 53.5 | 28 | 43 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.::GO:0008198; F:ferrous iron binding; IDA:UniProtKB.::GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; IDA:UniProtKB. | 4 | Q32L00 | 286 | ALKB3_BOVIN Alpha-ketoglutarate-dependent dio... | 134 | 0.000002 | 52.8 | 28 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; ISS:UniProtKB. | 5 | Q6P6J4 | 239 | ALKB2_MOUSE Alpha-ketoglutarate-dependent dio... | 157 | 0.002 | 43.1 | 24 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; ISS:UniProtKB.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035511; P:oxidative DNA demethylation; ISS:UniProtKB. | 6 | Q58DM4 | 278 | ALKB2_BOVIN Alpha-ketoglutarate-dependent dio... | 157 | 0.02 | 40.4 | 24 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; ISS:UniProtKB.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035511; P:oxidative DNA demethylation; ISS:UniProtKB. | 7 | Q6NS38 | 261 | ALKB2_HUMAN Alpha-ketoglutarate-dependent dio... | 153 | 0.021 | 40.4 | 24 | 36 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; IDA:UniProtKB.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.::GO:0008198; F:ferrous iron binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0035511; P:oxidative DNA demethylation; IDA:UniProtKB. | 8 | Q8K203 | 606 | NEIL3_MOUSE Endonuclease 8-like 3 OS=Mus musc... | 38 | 0.33 | 37 | 42 | 63 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0000405; F:bubble DNA binding; IDA:UniProtKB.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; IDA:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; IDA:UniProtKB.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 9 | Q9NXW9 | 302 | ALKB4_HUMAN Probable alpha-ketoglutarate-depe... | 58 | 0.18 | 37.4 | 36 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q5HZL1 | 687 | ERI2_XENLA ERI1 exoribonuclease 2 OS=Xenopus ... | 104 | 0.22 | 37.7 | 25 | 38 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 11 | O70157 | 1003 | TOP3A_MOUSE DNA topoisomerase 3-alpha OS=Mus ... | 44 | 0.25 | 37.7 | 41 | 48 | GO:0005694; C:chromosome; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro. | 12 | Q3MHN7 | 606 | NEIL3_BOVIN Endonuclease 8-like 3 OS=Bos taur... | 46 | 0.27 | 37.4 | 41 | 57 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0000405; F:bubble DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; ISS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.::GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 13 | Q8TAT5 | 605 | NEIL3_HUMAN Endonuclease 8-like 3 OS=Homo sap... | 38 | 1.2 | 35.4 | 39 | 61 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0000405; F:bubble DNA binding; ISS:UniProtKB.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019104; F:DNA N-glycosylase activity; ISS:UniProtKB.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.::GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro. | 14 | Q13472 | 1001 | TOP3A_HUMAN DNA topoisomerase 3-alpha OS=Homo... | 44 | 0.93 | 35.8 | 39 | 48 | GO:0005694; C:chromosome; IEA:InterPro.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0007126; P:meiosis; TAS:ProtInc. | 15 | Q68G58 | 516 | APEX2_MOUSE DNA-(apurinic or apyrimidinic sit... | 39 | 1.1 | 35.4 | 41 | 56 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 16 | Q5E9N9 | 514 | APEX2_BOVIN DNA-(apurinic or apyrimidinic sit... | 39 | 2.3 | 34.3 | 41 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:EC.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 17 | A8K979 | 691 | ERI2_HUMAN ERI1 exoribonuclease 2 OS=Homo sap... | 47 | 3.6 | 33.9 | 32 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 18 | Q5BKS4 | 688 | ERI2_MOUSE ERI1 exoribonuclease 2 OS=Mus musc... | 47 | 5.1 | 33.5 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | Q2NRM0 | 382 | LPXB_SODGM Lipid-A-disaccharide synthase OS=S... | 75 | 8.8 | 32.3 | 29 | 43 | | | | | | | | | | | GO:0008915; F:lipid-A-disaccharide synthase activity; IEA:EC. | | | | | | | | | | GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW. |