rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P82602 | 450 | FOLKP_CHLMU Folate synthesis bifunctional pro... | 479 | 2e-36 | 144 | 28 | 45 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 32 | P0A578 | 280 | DHPS1_MYCTU Dihydropteroate synthase 1 OS=Myc... | 300 | 4e-36 | 140 | 39 | 50 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IDA:MTBBASE.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.::GO:0046654; P:tetrahydrofolate biosynthetic process; IDA:MTBBASE. | 33 | P0A579 | 280 | DHPS1_MYCBO Dihydropteroate synthase 1 OS=Myc... | 300 | 4e-36 | 140 | 39 | 50 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 34 | Q821E2 | 447 | FOLKP_CHLCV Folate synthesis bifunctional pro... | 481 | 1e-31 | 130 | 28 | 46 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 35 | O84619 | 450 | FOLKP_CHLTR Folate synthesis bifunctional pro... | 468 | 4e-31 | 129 | 27 | 46 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 36 | Q9Z7E8 | 450 | FOLKP_CHLPN Folate synthesis bifunctional pro... | 480 | 2e-30 | 127 | 29 | 45 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 37 | P0AC12 | 271 | DHP2_SHIFL Dihydropteroate synthase type-2 OS... | 285 | 1e-26 | 113 | 33 | 50 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 38 | P0AC11 | 271 | DHP2_ECOLX Dihydropteroate synthase type-2 OS... | 285 | 1e-26 | 113 | 33 | 50 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 39 | P59655 | 314 | DHPS_STRR6 Dihydropteroate synthase OS=Strept... | 312 | 4e-26 | 112 | 33 | 53 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 40 | P05382 | 314 | DHPS_STRPN Dihydropteroate synthase OS=Strept... | 311 | 7e-26 | 112 | 33 | 51 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 41 | P29252 | 167 | HPPK_BACSU 2-amino-4-hydroxy-6-hydroxymethyld... | 128 | 9e-25 | 105 | 42 | 63 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 42 | P59657 | 270 | SULD_STRR6 Bifunctional folate synthesis prot... | 136 | 2e-24 | 107 | 45 | 63 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004150; F:dihydroneopterin aldolase activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 43 | P22291 | 270 | SULD_STRPN Bifunctional folate synthesis prot... | 136 | 3e-24 | 107 | 45 | 63 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004150; F:dihydroneopterin aldolase activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 44 | P71512 | 158 | HPPK_METEA 2-amino-4-hydroxy-6-hydroxymethyld... | 134 | 2e-23 | 101 | 41 | 60 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 45 | P43777 | 160 | HPPK_HAEIN 2-amino-4-hydroxy-6-hydroxymethyld... | 132 | 1e-22 | 99.8 | 42 | 60 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 46 | P0C0X2 | 291 | DHPS2_MYCLE Inactive dihydropteroate synthase... | 298 | 3e-22 | 101 | 34 | 47 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:InterPro. | | | | | | | | | | GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro. | 47 | Q8GJP4 | 349 | FOLKE_LACLM Bifunctional protein folKE OS=Lac... | 142 | 3e-21 | 99 | 36 | 61 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003934; F:GTP cyclohydrolase I activity; IEA:EC.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro. | 48 | O66550 | 160 | HPPK_AQUAE 2-amino-4-hydroxy-6-hydroxymethyld... | 131 | 6e-21 | 94.7 | 36 | 64 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 49 | P0C0G2 | 166 | HPPK_STRPY 2-amino-4-hydroxy-6-hydroxymethyld... | 152 | 2e-19 | 90.5 | 38 | 53 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 50 | P0C0G3 | 166 | HPPK_STRP1 2-amino-4-hydroxy-6-hydroxymethyld... | 152 | 2e-19 | 90.5 | 38 | 53 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 51 | Q49184 | 283 | DHP1_MYCFO Dihydropteroate synthase type-1 OS... | 313 | 3e-19 | 92.4 | 27 | 44 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 52 | P0C003 | 279 | DHP1_PSEAI Dihydropteroate synthase type-1 OS... | 310 | 1e-18 | 90.5 | 27 | 45 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 53 | P0C002 | 279 | DHP1_ECOLX Dihydropteroate synthase type-1 OS... | 310 | 1e-18 | 90.5 | 27 | 45 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 54 | P0C004 | 279 | DHP1_CORGT Dihydropteroate synthase type-1 OS... | 310 | 1e-18 | 90.5 | 27 | 45 | | | | | | | | | | | GO:0004156; F:dihydropteroate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 55 | Q8P151 | 166 | HPPK_STRP8 2-amino-4-hydroxy-6-hydroxymethyld... | 152 | 1e-18 | 88.6 | 37 | 53 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 56 | P0DB11 | 162 | HPPK_STRPQ 2-amino-4-hydroxy-6-hydroxymethyld... | 152 | 2e-18 | 87.4 | 38 | 53 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 57 | P0DB10 | 162 | HPPK_STRP3 2-amino-4-hydroxy-6-hydroxymethyld... | 152 | 2e-18 | 87.4 | 38 | 53 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 58 | Q5XCA6 | 166 | HPPK_STRP6 2-amino-4-hydroxy-6-hydroxymethyld... | 152 | 2e-18 | 87.4 | 37 | 53 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 59 | P72736 | 195 | HPPK_SYNY3 2-amino-4-hydroxy-6-hydroxymethyld... | 147 | 5e-17 | 84.3 | 37 | 52 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. | 60 | P26281 | 159 | HPPK_ECOLI 2-amino-4-hydroxy-6-hydroxymethyld... | 139 | 2e-16 | 82 | 36 | 55 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IDA:EcoCyc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:EcoCyc. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IDA:EcoliWiki. | 61 | Q9HV71 | 162 | HPPK_PSEAE 2-amino-4-hydroxy-6-hydroxymethyld... | 133 | 7e-16 | 80.1 | 43 | 60 | | | | | | | | | | | GO:0003848; F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW. |