rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q8R2V5 | 381 | ADAP2_MOUSE Arf-GAP with dual PH domain-conta... | 62 | 0.0000007 | 55.1 | 44 | 52 | GO:0005740; C:mitochondrial envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; NAS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 92 | Q9Z272 | 770 | GIT1_RAT ARF GTPase-activating protein GIT1 O... | 71 | 0.0000008 | 55.5 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0031267; F:small GTPase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:RGD. | 93 | Q9Y2X7 | 761 | GIT1_HUMAN ARF GTPase-activating protein GIT1... | 71 | 0.0000009 | 55.1 | 30 | 52 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc. | 94 | Q9NPF8 | 381 | ADAP2_HUMAN Arf-GAP with dual PH domain-conta... | 79 | 0.000001 | 54.3 | 35 | 51 | GO:0005740; C:mitochondrial envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0030674; F:protein binding, bridging; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007507; P:heart development; IEP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 95 | Q68FF6 | 770 | GIT1_MOUSE ARF GTPase-activating protein GIT1... | 71 | 0.000001 | 55.1 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 96 | P40956 | 396 | GTS1_YEAST Protein GTS1 OS=Saccharomyces cere... | 105 | 0.000002 | 53.9 | 30 | 50 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IMP:SGD.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0000989; F:transcription factor binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:SGD.::GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007624; P:ultradian rhythm; IMP:SGD. | 97 | Q4KLH5 | 561 | AGFG1_RAT Arf-GAP domain and FG repeat-contai... | 88 | 0.000007 | 52.4 | 30 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 98 | Q8K2K6 | 561 | AGFG1_MOUSE Arf-GAP domain and FG repeat-cont... | 88 | 0.000007 | 52.4 | 30 | 53 | GO:0042995; C:cell projection; IDA:MGI.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0045109; P:intermediate filament organization; IMP:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007289; P:spermatid nucleus differentiation; IMP:MGI.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 99 | Q2TA45 | 562 | AGFG1_BOVIN Arf-GAP domain and FG repeat-cont... | 88 | 0.000007 | 52 | 30 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 100 | P52594 | 562 | AGFG1_HUMAN Arf-GAP domain and FG repeat-cont... | 88 | 0.000008 | 52 | 30 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 101 | Q1ZXH8 | 1632 | GXCDD_DICDI Guanine exchange factor for Rac 3... | 96 | 0.00002 | 51.6 | 34 | 54 | GO:0005938; C:cell cortex; IMP:dictyBase.::GO:0032009; C:early phagosome; IMP:dictyBase.::GO:0005626; C:insoluble fraction; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:dictyBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IDA:dictyBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IPI:dictyBase. | 102 | Q04412 | 482 | AGE1_YEAST ADP-ribosylation factor GTPase-act... | 55 | 0.00006 | 49.3 | 42 | 55 | GO:0005768; C:endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IGI:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 103 | Q8RXE7 | 649 | AGD14_ARATH Probable ADP-ribosylation factor ... | 94 | 0.00007 | 49.3 | 23 | 50 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 104 | Q80WC7 | 479 | AGFG2_MOUSE Arf-GAP domain and FG repeat-cont... | 151 | 0.016 | 41.2 | 25 | 43 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 105 | O95081 | 481 | AGFG2_HUMAN Arf-GAP domain and FG repeat-cont... | 88 | 0.051 | 39.7 | 26 | 49 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 106 | Q8N6H7 | 521 | ARFG2_HUMAN ADP-ribosylation factor GTPase-ac... | 54 | 0.19 | 38.1 | 52 | 67 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 107 | O23469 | 245 | GDL63_ARATH GDSL esterase/lipase At4g16220 OS... | 64 | 0.23 | 37 | 34 | 55 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 108 | Q3AZ58 | 186 | MTND_SYNS9 Acireductone dioxygenase OS=Synech... | 61 | 0.65 | 35.4 | 36 | 52 | | | | | | | | | | | GO:0010308; F:acireductone dioxygenase (Ni2+-requiring) activity; IEA:EC.::GO:0010309; F:acireductone dioxygenase [iron(II)-requiring activity; IEA:EC.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016151; F:nickel cation binding; IEA:InterPro. | | | | | | | | | | GO:0019284; P:L-methionine biosynthetic process from S-adenosylmethionine; IEA:InterPro.] | 109 | Q5R4T3 | 268 | MLF1_PONAB Myeloid leukemia factor 1 OS=Pongo... | 60 | 3.1 | 33.5 | 32 | 57 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0002318; P:myeloid progenitor cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB. | 110 | P39083 | 1007 | RGA1_YEAST Rho-type GTPase-activating protein... | 127 | 4.5 | 33.9 | 24 | 41 | GO:0032177; C:cellular bud neck split septin rings; IDA:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:SGD.::GO:0007118; P:budding cell apical bud growth; IPI:SGD.::GO:0007119; P:budding cell isotropic bud growth; IPI:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IPI:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD.::GO:0007124; P:pseudohyphal growth; IPI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 111 | P58340 | 268 | MLF1_HUMAN Myeloid leukemia factor 1 OS=Homo ... | 60 | 8.1 | 32.3 | 32 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0002318; P:myeloid progenitor cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB. |