rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O60070 | 652 | ASH2_SCHPO Set1 complex component ash2 OS=Sch... | 467 | 1e-66 | 235 | 34 | 47 | GO:0048189; C:Lid2 complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase. | 2 | P43132 | 505 | BRE2_YEAST COMPASS component BRE2 OS=Saccharo... | 518 | 3e-35 | 142 | 26 | 42 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0080182; P:histone H3-K4 trimethylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 3 | Q91X20 | 623 | ASH2L_MOUSE Set1/Ash2 histone methyltransfera... | 308 | 5e-17 | 88.6 | 24 | 36 | GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q9UBL3 | 628 | ASH2L_HUMAN Set1/Ash2 histone methyltransfera... | 308 | 9e-17 | 87.4 | 24 | 37 | GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0030097; P:hemopoiesis; NAS:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 5 | E9PZQ0 | 5035 | RYR1_MOUSE Ryanodine receptor 1 OS=Mus muscul... | 110 | 0.023 | 41.6 | 29 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030314; C:junctional membrane complex; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:UniProtKB.::GO:0030315; C:T-tubule; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IMP:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; IMP:UniProtKB.::GO:0006936; P:muscle contraction; IMP:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; IMP:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; IMP:UniProtKB.::GO:0006937; P:regulation of muscle contraction; TAS:MGI.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IMP:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; IMP:UniProtKB.::GO:0043588; P:skin development; IMP:UniProtKB. | 6 | P11716 | 5037 | RYR1_RABIT Ryanodine receptor 1 OS=Oryctolagu... | 110 | 0.024 | 41.6 | 29 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:UniProtKB.::GO:0014802; C:terminal cisterna; IDA:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IDA:BHF-UCL.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 7 | P16960 | 5035 | RYR1_PIG Ryanodine receptor 1 OS=Sus scrofa (... | 110 | 0.042 | 40.8 | 29 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 8 | P21817 | 5038 | RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapie... | 110 | 0.046 | 40.8 | 29 | 40 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0031674; C:I band; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0014701; C:junctional sarcoplasmic reticulum membrane; TAS:BHF-UCL.::GO:0005790; C:smooth endoplasmic reticulum; TAS:ProtInc.::GO:0014802; C:terminal cisterna; ISS:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; ISS:BHF-UCL.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:BHF-UCL.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 9 | Q9SIZ8 | 1280 | RKP_ARATH E3 ubiquitin-protein ligase RKP OS=... | 85 | 0.25 | 38.1 | 32 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060154; P:cellular process regulating host cell cycle in response to virus; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 10 | Q15413 | 4870 | RYR3_HUMAN Ryanodine receptor 3 OS=Homo sapie... | 112 | 0.54 | 37.4 | 28 | 41 | GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071318; P:cellular response to ATP; ISS:UniProtKB.::GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB. | 11 | A2AGL3 | 4863 | RYR3_MOUSE Ryanodine receptor 3 OS=Mus muscul... | 112 | 1.2 | 36.2 | 27 | 41 | GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0030314; C:junctional membrane complex; IDA:MGI.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0071318; P:cellular response to ATP; ISS:UniProtKB.::GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006941; P:striated muscle contraction; IMP:MGI. | 12 | Q9L7Q2 | 1906 | ZMPB_STRPN Zinc metalloprotease zmpB OS=Strep... | 184 | 2.1 | 35.4 | 23 | 36 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | F1LMY4 | 5035 | RYR1_RAT Ryanodine receptor 1 OS=Rattus norve... | 110 | 2.5 | 35 | 28 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.::GO:0006936; P:muscle contraction; ISS:UniProtKB.::GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.::GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.::GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.::GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.::GO:0043588; P:skin development; ISS:UniProtKB. | 14 | Q24498 | 5127 | RY44_DROME Ryanodine receptor 44F OS=Drosophi... | 113 | 4.4 | 34.3 | 27 | 38 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005219; F:ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006936; P:muscle contraction; IMP:UniProtKB. | 15 | Q2H988 | 894 | SET2_CHAGB Histone-lysine N-methyltransferase... | 70 | 8.6 | 33.1 | 33 | 44 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q2N9B2 | 207 | RL4_ERYLH 50S ribosomal protein L4 OS=Erythro... | 153 | 9.6 | 32.3 | 24 | 41 | GO:0005840; C:ribosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0006412; P:translation; IEA:InterPro. |