rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q4U3Y2 | 549 | HXK1_ASPFU Hexokinase-1 OS=A1100) (Aspergillu... | 440 | 7e-30 | 126 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 2 | P17712 | 465 | HXK4_RAT Glucokinase OS=Rattus norvegicus (Ra... | 297 | 6e-23 | 105 | 29 | 46 | GO:0044448; C:cell cortex part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD. | | | | | | | | | | GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0001678; P:cellular glucose homeostasis; IMP:RGD.::GO:0042149; P:cellular response to glucose starvation; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IDA:RGD.::GO:0005978; P:glycogen biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:RGD.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:RGD.::GO:0019932; P:second-messenger-mediated signaling; IDA:RGD. | 3 | Q9SQ76 | 496 | HXK2_SOLTU Hexokinase-2 OS=Solanum tuberosum ... | 461 | 8e-23 | 105 | 28 | 42 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 4 | P52792 | 465 | HXK4_MOUSE Glucokinase OS=Mus musculus (Mouse... | 342 | 9e-23 | 104 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB. | | | | | | | | | | GO:0070509; P:calcium ion import; IMP:UniProtKB.::GO:0001678; P:cellular glucose homeostasis; IMP:MGI.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006739; P:NADP metabolic process; IMP:MGI.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0043266; P:regulation of potassium ion transport; IMP:MGI. | 5 | O08528 | 917 | HXK2_MOUSE Hexokinase-2 OS=Mus musculus (Mous... | 345 | 2e-22 | 105 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0046324; P:regulation of glucose import; IMP:MGI. | 6 | Q1W674 | 917 | HXK2_PIG Hexokinase-2 OS=Sus scrofa (Pig). GN... | 345 | 4e-21 | 101 | 28 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 7 | P27881 | 917 | HXK2_RAT Hexokinase-2 OS=Rattus norvegicus (R... | 345 | 2e-22 | 105 | 29 | 44 | GO:0005741; C:mitochondrial outer membrane; TAS:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0007595; P:lactation; IEP:RGD. | 8 | A2PYL6 | 917 | HXK2_HORSE Hexokinase-2 OS=Equus caballus (Ho... | 345 | 3e-22 | 105 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 9 | A2PYL7 | 917 | HXK2_EQUZE Hexokinase-2 OS=Equus zebra (Mount... | 345 | 3e-22 | 105 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 10 | A2PYL8 | 917 | HXK2_EQUGR Hexokinase-2 OS=Equus grevyi (Grev... | 345 | 3e-22 | 105 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 11 | Q2TB90 | 917 | HKDC1_HUMAN Putative hexokinase HKDC1 OS=Homo... | 306 | 6e-21 | 100 | 28 | 44 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 12 | P52789 | 917 | HXK2_HUMAN Hexokinase-2 OS=Homo sapiens (Huma... | 345 | 6e-21 | 100 | 28 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc. | | | | | | | | | | GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 13 | P35557 | 465 | HXK4_HUMAN Glucokinase OS=Homo sapiens (Human... | 297 | 5e-22 | 102 | 28 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004340; F:glucokinase activity; IDA:UniProtKB.::GO:0005536; F:glucose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.::GO:0051594; P:detection of glucose; IMP:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0006110; P:regulation of glycolysis; NAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 14 | P19367 | 917 | HXK1_HUMAN Hexokinase-1 OS=Homo sapiens (Huma... | 334 | 3e-19 | 95.5 | 29 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc. | | | | | | | | | | GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 15 | Q9SEK2 | 497 | HXK1_TOBAC Hexokinase-1 OS=Nicotiana tabacum ... | 465 | 1e-21 | 101 | 27 | 41 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 16 | P27926 | 924 | HXK3_RAT Hexokinase-3 OS=Rattus norvegicus (R... | 382 | 0.00000000001 | 71.6 | 27 | 40 | GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD.::GO:0042562; F:hormone binding; IPI:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 17 | Q91W97 | 915 | HKDC1_MOUSE Putative hexokinase HKDC1 OS=Mus ... | 334 | 3e-21 | 101 | 28 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 18 | Q5RC71 | 917 | HXK1_PONAB Hexokinase-1 OS=Pongo abelii (Suma... | 332 | 5e-20 | 97.8 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 19 | P50506 | 478 | HXK_SCHOC Hexokinase OS=Schwanniomyces occide... | 294 | 6e-21 | 99.8 | 31 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 20 | Q3TRM8 | 922 | HXK3_MOUSE Hexokinase-3 OS=Mus musculus (Mous... | 375 | 0.0000000001 | 68.2 | 27 | 39 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 21 | P17710 | 974 | HXK1_MOUSE Hexokinase-1 OS=Mus musculus (Mous... | 339 | 8e-20 | 97.4 | 29 | 45 | GO:0005829; C:cytosol; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI. | | | | | | | | | | GO:0006096; P:glycolysis; TAS:MGI. | 22 | P52790 | 923 | HXK3_HUMAN Hexokinase-3 OS=Homo sapiens (Huma... | 341 | 0.0000000003 | 66.6 | 27 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004396; F:hexokinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; NAS:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 23 | Q09756 | 484 | HXK1_SCHPO Hexokinase-1 OS=Schizosaccharomyce... | 561 | 3e-20 | 97.4 | 25 | 38 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase. | | | | | | | | | | GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IC:PomBase.::GO:0006013; P:mannose metabolic process; IDA:PomBase.::GO:0009051; P:pentose-phosphate shunt, oxidative branch; TAS:PomBase. | 24 | Q9NFT7 | 486 | HXK2_DROME Hexokinase type 2 OS=Drosophila me... | 289 | 4e-20 | 97.1 | 30 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006096; P:glycolysis; NAS:UniProtKB. | 25 | P05708 | 918 | HXK1_RAT Hexokinase-1 OS=Rattus norvegicus (R... | 329 | 4e-19 | 95.1 | 28 | 44 | GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0016887; F:ATPase activity; IC:RGD.::GO:0004340; F:glucokinase activity; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004672; F:protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0010359; P:regulation of anion channel activity; IDA:RGD. | 26 | Q1WM16 | 463 | HXK7_ORYSJ Hexokinase-7 OS=Oryza sativa subsp... | 306 | 7e-20 | 96.3 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 27 | P33284 | 485 | HXK_KLULA Hexokinase OS=1267 / NRRL Y-1140 / ... | 289 | 1e-19 | 95.9 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 28 | P83776 | 484 | HXKB_CANAL Hexokinase-2 OS=Candida albicans (... | 288 | 4e-19 | 94 | 30 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 29 | P27595 | 918 | HXK1_BOVIN Hexokinase-1 OS=Bos taurus (Bovine... | 394 | 6e-19 | 94.4 | 24 | 43 | GO:0005829; C:cytosol; ISS:AgBase.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; ISS:AgBase. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 30 | P80581 | 490 | HXK_EMENI Hexokinase OS=194 / M139) (Aspergil... | 380 | 6e-19 | 93.6 | 28 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 31 | P93834 | 502 | HXK2_ARATH Hexokinase-2 OS=Arabidopsis thalia... | 459 | 1e-18 | 92.4 | 26 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0009536; C:plastid; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:TAIR.::GO:0004340; F:glucokinase activity; IDA:TAIR. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009747; P:hexokinase-dependent signaling; IMP:TAIR.::GO:0012501; P:programmed cell death; IMP:TAIR. |