rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P07943 | 316 | ALDR_RAT Aldose reductase OS=Rattus norvegicu... | 305 | 9e-53 | 182 | 37 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:RGD. | | | | | | | | | | GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.::GO:0006061; P:sorbitol biosynthetic process; IMP:RGD.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD. | 62 | P15122 | 316 | ALDR_RABIT Aldose reductase OS=Oryctolagus cu... | 305 | 1e-52 | 182 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 63 | Q5REQ0 | 323 | AK1C1_PONAB Aldo-keto reductase family 1 memb... | 319 | 1e-52 | 182 | 34 | 52 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 64 | P80508 | 323 | PE2R_RABIT Prostaglandin-E(2) 9-reductase OS=... | 315 | 2e-52 | 181 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 65 | A0QV10 | 275 | Y2408_MYCS2 Uncharacterized oxidoreductase MS... | 313 | 2e-52 | 180 | 37 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 66 | Q9TV64 | 326 | AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen... | 317 | 3e-52 | 181 | 35 | 51 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 67 | Q10494 | 321 | YDG7_SCHPO Uncharacterized oxidoreductase C26... | 320 | 5e-52 | 180 | 35 | 53 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 68 | Q5R7C9 | 323 | AK1C3_PONAB Aldo-keto reductase family 1 memb... | 330 | 1e-51 | 179 | 34 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB. | 69 | Q95JH5 | 323 | AK1C4_MACFA Aldo-keto reductase family 1 memb... | 317 | 2e-51 | 179 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 70 | P80276 | 316 | ALDR_PIG Aldose reductase OS=Sus scrofa (Pig)... | 301 | 2e-51 | 178 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 71 | Q02198 | 296 | MORA_PSEPU Morphine 6-dehydrogenase OS=Pseudo... | 316 | 2e-51 | 178 | 36 | 53 | | | | | | | | | | | GO:0050109; F:morphine 6-dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW. | 72 | Q95JH4 | 323 | AK1C4_MACFU Aldo-keto reductase family 1 memb... | 317 | 3e-51 | 178 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC. | | | | | | | | | | | 73 | A4TE41 | 279 | Y4205_MYCGI Uncharacterized oxidoreductase Mf... | 314 | 5e-51 | 176 | 34 | 51 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 74 | Q5ZK84 | 327 | AK1A1_CHICK Alcohol dehydrogenase [NADP(+)] O... | 311 | 8e-51 | 177 | 35 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 75 | P21300 | 316 | ALD1_MOUSE Aldose reductase-related protein 1... | 319 | 2e-50 | 176 | 36 | 54 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:MGI. | 76 | Q0PGJ6 | 315 | AKRC9_ARATH Aldo-keto reductase family 4 memb... | 313 | 2e-50 | 176 | 35 | 50 | GO:0009507; C:chloroplast; IDA:TAIR. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 77 | Q5U1Y4 | 301 | AKCL2_RAT 1,5-anhydro-D-fructose reductase OS... | 305 | 3e-50 | 175 | 35 | 54 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 78 | Q6GMC7 | 327 | AK1A1_XENLA Alcohol dehydrogenase [NADP(+)] O... | 336 | 4e-50 | 175 | 35 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 79 | P17516 | 323 | AK1C4_HUMAN Aldo-keto reductase family 1 memb... | 317 | 4e-50 | 175 | 32 | 54 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB. | 80 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 317 | 4e-50 | 175 | 33 | 54 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. | 81 | P31210 | 326 | AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenas... | 322 | 9e-50 | 174 | 34 | 50 | | | | | | | | | | | GO:0047568; F:3-oxo-5-beta-steroid 4-dehydrogenase activity; IDA:MGI.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 82 | Q5RJP0 | 316 | ALD1_RAT Aldose reductase-related protein 1 O... | 317 | 1e-49 | 174 | 36 | 52 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:RGD. | | | | | | | | | | | 83 | A1UEC6 | 276 | Y1985_MYCSK Uncharacterized oxidoreductase Mk... | 318 | 1e-49 | 172 | 35 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 84 | Q28FD1 | 327 | AK1A1_XENTR Alcohol dehydrogenase [NADP(+)] O... | 335 | 2e-49 | 174 | 35 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 85 | Q8K023 | 323 | AKC1H_MOUSE Aldo-keto reductase family 1 memb... | 323 | 2e-49 | 173 | 33 | 53 | | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0007567; P:parturition; IMP:MGI.::GO:0006709; P:progesterone catabolic process; IDA:MGI. | 86 | Q1XAA8 | 322 | AK1CN_HORSE Aldo-keto reductase family 1 memb... | 314 | 2e-49 | 173 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 87 | P23457 | 322 | DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase... | 317 | 9e-49 | 171 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC. | | | | | | | | | | GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD. | 88 | A3PXT0 | 276 | Y1919_MYCSJ Uncharacterized oxidoreductase Mj... | 318 | 1e-48 | 170 | 35 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 89 | A1T726 | 279 | Y2161_MYCVP Uncharacterized oxidoreductase Mv... | 314 | 2e-48 | 169 | 35 | 51 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | P17264 | 324 | CRO_LITCT Rho crystallin OS=Lithobates catesb... | 322 | 3e-48 | 170 | 35 | 53 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 91 | P02532 | 324 | CRO_RANTE Rho crystallin OS=Rana temporaria (... | 322 | 3e-48 | 170 | 35 | 53 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | |