rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q3ZCJ2 | 325 | AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O... | 342 | 2e-61 | 205 | 36 | 54 | | | | | | | | | | | | | | | | | | | | | | 32 | P50578 | 325 | AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=... | 342 | 1e-60 | 202 | 35 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 33 | P14550 | 325 | AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O... | 341 | 3e-60 | 202 | 35 | 54 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc. | 34 | Q5R5D5 | 325 | AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O... | 341 | 1e-59 | 200 | 35 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 35 | P82125 | 301 | AKCL2_PIG 1,5-anhydro-D-fructose reductase OS... | 305 | 9e-59 | 197 | 35 | 55 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 36 | Q6AZW2 | 324 | A1A1A_DANRE Alcohol dehydrogenase [NADP(+)] A... | 318 | 1e-58 | 197 | 36 | 54 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 37 | Q95JH6 | 323 | AK1C1_MACFU Aldo-keto reductase family 1 memb... | 316 | 5e-57 | 193 | 36 | 53 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 38 | P52898 | 323 | DDBX_BOVIN Dihydrodiol dehydrogenase 3 OS=Bos... | 316 | 5e-57 | 193 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 39 | P52895 | 323 | AK1C2_HUMAN Aldo-keto reductase family 1 memb... | 316 | 9e-57 | 192 | 37 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB. | 40 | Q95JH7 | 323 | AK1C1_MACFA Aldo-keto reductase family 1 memb... | 316 | 1e-56 | 192 | 36 | 53 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 41 | Q568L5 | 324 | A1A1B_DANRE Alcohol dehydrogenase [NADP(+)] B... | 314 | 2e-56 | 191 | 37 | 55 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 42 | O60218 | 316 | AK1BA_HUMAN Aldo-keto reductase family 1 memb... | 305 | 3e-56 | 191 | 37 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:ProtInc. | 43 | P05980 | 323 | PGFS1_BOVIN Prostaglandin F synthase 1 OS=Bos... | 317 | 4e-56 | 191 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 44 | P15121 | 316 | ALDR_HUMAN Aldose reductase OS=Homo sapiens (... | 302 | 9e-56 | 190 | 39 | 57 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.::GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.::GO:0006950; P:response to stress; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 45 | Q04828 | 323 | AK1C1_HUMAN Aldo-keto reductase family 1 memb... | 316 | 9e-56 | 190 | 36 | 53 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.::GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB. | 46 | Q84TF0 | 314 | AKRCA_ARATH Aldo-keto reductase family 4 memb... | 306 | 2e-55 | 189 | 36 | 54 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | O80944 | 311 | AKRC8_ARATH Aldo-keto reductase family 4 memb... | 303 | 3e-55 | 188 | 38 | 55 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 48 | P52897 | 323 | PGFS2_BOVIN Prostaglandin F synthase 2 OS=Bos... | 317 | 3e-55 | 188 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC. | | | | | | | | | | GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW. | 49 | P27800 | 323 | ALDX_SPOSA Aldehyde reductase 1 OS=Sporobolom... | 321 | 5e-55 | 188 | 38 | 54 | GO:0005623; C:cell; IDA:UniProtKB. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB. | | | | | | | | | | | 50 | Q6W8P9 | 323 | AK1CO_HORSE Aldo-keto reductase family 1 memb... | 313 | 7e-55 | 187 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 51 | P16116 | 315 | ALDR_BOVIN Aldose reductase OS=Bos taurus (Bo... | 304 | 5e-54 | 185 | 38 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 52 | Q8VCX1 | 325 | AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen... | 321 | 5e-54 | 185 | 36 | 51 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 53 | Q4R802 | 320 | AKCL2_MACFA 1,5-anhydro-D-fructose reductase ... | 317 | 6e-54 | 185 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 54 | P51857 | 326 | AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen... | 322 | 7e-54 | 185 | 34 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB. | 55 | Q96JD6 | 320 | AKCL2_HUMAN 1,5-anhydro-D-fructose reductase ... | 316 | 2e-53 | 184 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 56 | P45376 | 316 | ALDR_MOUSE Aldose reductase OS=Mus musculus (... | 305 | 4e-53 | 182 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI. | | | | | | | | | | | 57 | P45377 | 316 | ALD2_MOUSE Aldose reductase-related protein 2... | 305 | 4e-53 | 182 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 58 | P42330 | 323 | AK1C3_HUMAN Aldo-keto reductase family 1 memb... | 330 | 5e-53 | 183 | 35 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB. | 59 | Q8SSK6 | 301 | ALDR_ENCCU Aldose reductase OS=Encephalitozoo... | 325 | 5e-53 | 182 | 34 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 60 | P70694 | 323 | DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 ... | 320 | 7e-53 | 182 | 34 | 54 | | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IDA:MGI. | 61 | P07943 | 316 | ALDR_RAT Aldose reductase OS=Rattus norvegicu... | 305 | 9e-53 | 182 | 37 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:RGD. | | | | | | | | | | GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.::GO:0006061; P:sorbitol biosynthetic process; IMP:RGD.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD. |