rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9VE01 | 536 | C12A5_DROME Probable cytochrome P450 12a5, mi... | 198 | 0.00000000008 | 67.8 | 25 | 45 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 62 | Q04552 | 498 | CP6B1_PAPPO Cytochrome P450 6B1 OS=Papilio po... | 188 | 0.0000000001 | 67.8 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 63 | O09158 | 503 | CP3AP_MOUSE Cytochrome P450 3A25 OS=Mus muscu... | 262 | 0.0000000001 | 67.8 | 23 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 64 | Q9LZ31 | 512 | C77A4_ARATH Cytochrome P450 77A4 OS=Arabidops... | 175 | 0.0000000001 | 67.4 | 29 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019395; P:fatty acid oxidation; IDA:UniProtKB. | 65 | Q59990 | 444 | CP120_SYNY3 Putative cytochrome P450 120 OS=S... | 366 | 0.0000000001 | 67 | 24 | 40 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 66 | P24464 | 508 | CP4AC_RAT Cytochrome P450 4A12 OS=Rattus norv... | 191 | 0.0000000002 | 67 | 29 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 67 | P15129 | 511 | CP4B1_RAT Cytochrome P450 4B1 OS=Rattus norve... | 192 | 0.0000000002 | 67 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008144; F:drug binding; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0018585; F:fluorene oxygenase activity; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0018879; P:biphenyl metabolic process; IMP:RGD.::GO:0042738; P:exogenous drug catabolic process; IDA:RGD.::GO:0018917; P:fluorene metabolic process; IDA:RGD. | 68 | P17177 | 535 | CP27A_RABIT Sterol 26-hydroxylase, mitochondr... | 195 | 0.0000000002 | 67 | 30 | 44 | | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 69 | Q9V4U9 | 493 | C6A13_DROME Probable cytochrome P450 6a13 OS=... | 221 | 0.0000000002 | 66.6 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 70 | Q9LTL0 | 500 | C71BQ_ARATH Cytochrome P450 71B26 OS=Arabidop... | 302 | 0.0000000002 | 66.6 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 71 | P24463 | 503 | CP3AC_CANFA Cytochrome P450 3A12 OS=Canis fam... | 261 | 0.0000000002 | 66.6 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 72 | O15528 | 508 | CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydro... | 249 | 0.0000000002 | 66.6 | 28 | 43 | GO:0005741; C:mitochondrial outer membrane; TAS:Reactome. | | | | | | | | | | GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0030282; P:bone mineralization; IEP:BHF-UCL.::GO:0055074; P:calcium ion homeostasis; IMP:BHF-UCL.::GO:0006816; P:calcium ion transport; ISS:BHF-UCL.::GO:0046697; P:decidualization; IEP:BHF-UCL.::GO:0070314; P:G1 to G0 transition; IMP:BHF-UCL.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:BHF-UCL.::GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0070564; P:positive regulation of vitamin D receptor signaling pathway; IDA:BHF-UCL.::GO:0030500; P:regulation of bone mineralization; IMP:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IEP:BHF-UCL.::GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IEP:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IEP:BHF-UCL.::GO:0033280; P:response to vitamin D; IEP:BHF-UCL.::GO:0042368; P:vitamin D biosynthetic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 73 | P15128 | 506 | CP4B1_RABIT Cytochrome P450 4B1 OS=Oryctolagu... | 189 | 0.0000000002 | 66.6 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 74 | Q92045 | 514 | CP11A_DASAM Cholesterol side-chain cleavage e... | 190 | 0.0000000002 | 66.6 | 24 | 45 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 75 | P14581 | 511 | CP4A7_RABIT Cytochrome P450 4A7 OS=Oryctolagu... | 191 | 0.0000000003 | 66.2 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 76 | Q02928 | 519 | CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi... | 191 | 0.0000000003 | 66.2 | 27 | 44 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 77 | Q63688 | 414 | CP7B1_RAT 25-hydroxycholesterol 7-alpha-hydro... | 213 | 0.0000000003 | 65.9 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; TAS:RGD. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:RGD.::GO:0008203; P:cholesterol metabolic process; TAS:RGD.::GO:0007623; P:circadian rhythm; IDA:RGD.::GO:0007613; P:memory; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD. | 78 | Q7KR10 | 521 | CCD1D_DROME Probable cytochrome P450 12d1 dis... | 209 | 0.0000000003 | 66.2 | 22 | 44 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030342; F:1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 79 | O35728 | 507 | CP4AE_MOUSE Cytochrome P450 4A14 OS=Mus muscu... | 217 | 0.0000000003 | 65.9 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 80 | Q64581 | 497 | CP3AI_RAT Cytochrome P450 3A18 OS=Rattus norv... | 262 | 0.0000000004 | 65.9 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008390; F:testosterone 16-alpha-hydroxylase activity; IDA:RGD.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | | 81 | Q9W223 | 512 | CP6D2_DROME Probable cytochrome P450 6d2 OS=D... | 205 | 0.0000000004 | 65.9 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 82 | Q02318 | 531 | CP27A_HUMAN Sterol 26-hydroxylase, mitochondr... | 278 | 0.0000000004 | 65.9 | 26 | 42 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 83 | P37124 | 511 | C77A2_SOLME Cytochrome P450 77A2 OS=Solanum m... | 172 | 0.0000000004 | 65.5 | 26 | 46 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 84 | P48420 | 547 | C78A1_MAIZE Cytochrome P450 78A1 OS=Zea mays ... | 199 | 0.0000000004 | 65.9 | 27 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 85 | Q64406 | 503 | CP3AF_CAVPO Cytochrome P450 3A15 OS=Cavia por... | 211 | 0.0000000004 | 65.5 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 86 | Q759W0 | 529 | CP51_ASHGO Lanosterol 14-alpha demethylase OS... | 230 | 0.0000000005 | 65.5 | 27 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 87 | Q964T1 | 501 | CP4CU_BLAGE Cytochrome P450 4c21 OS=Blattella... | 254 | 0.0000000005 | 65.5 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 88 | Q42799 | 502 | C93A2_SOYBN Cytochrome P450 93A2 OS=Glycine m... | 277 | 0.0000000005 | 65.1 | 23 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 89 | Q60991 | 507 | CP7B1_MOUSE 25-hydroxycholesterol 7-alpha-hyd... | 230 | 0.0000000006 | 65.1 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0007586; P:digestion; TAS:UniProtKB.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:MGI.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:MGI.::GO:0060740; P:prostate gland epithelium morphogenesis; IMP:MGI. | 90 | Q27698 | 516 | CP6D1_MUSDO Cytochrome P450 6d1 OS=Musca dome... | 176 | 0.0000000006 | 65.1 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 91 | Q9LTM7 | 502 | C71BG_ARATH Cytochrome P450 71B16 OS=Arabidop... | 261 | 0.0000000006 | 65.1 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |