| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | P49446 | 699 | PTPRE_MOUSE Receptor-type tyrosine-protein ph... | 175 | 0.003 | 45.4 | 22 | 37 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI. | 272 | P28827 | 1452 | PTPRM_HUMAN Receptor-type tyrosine-protein ph... | 28 | 0.082 | 40.8 | 54 | 71 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB. | 273 | Q15262 | 1439 | PTPRK_HUMAN Receptor-type tyrosine-protein ph... | 27 | 0.15 | 40 | 52 | 74 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 274 | P18052 | 829 | PTPRA_MOUSE Receptor-type tyrosine-protein ph... | 33 | 0.001 | 46.6 | 52 | 79 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 275 | Q63475 | 1004 | PTPR2_RAT Receptor-type tyrosine-protein phos... | 59 | 0.011 | 43.5 | 34 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034260; P:negative regulation of GTPase activity; IDA:RGD. | 276 | P32587 | 303 | PYP3_SCHPO Tyrosine-protein phosphatase 3 OS=... | 125 | 0.00002 | 51.6 | 28 | 39 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 277 | O02695 | 1013 | PTPR2_MACNE Receptor-type tyrosine-protein ph... | 59 | 0.018 | 43.1 | 34 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 278 | O82656 | 340 | PTP1_ARATH Protein-tyrosine-phosphatase PTP1 ... | 38 | 0.23 | 38.9 | 45 | 66 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; TAS:TAIR. | 279 | Q92932 | 1015 | PTPR2_HUMAN Receptor-type tyrosine-protein ph... | 59 | 0.019 | 43.1 | 34 | 58 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 280 | Q16849 | 979 | PTPRN_HUMAN Receptor-type tyrosine-protein ph... | 59 | 0.014 | 43.5 | 34 | 56 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB. | 281 | P56722 | 979 | PTPRN_BOVIN Receptor-type tyrosine-protein ph... | 59 | 0.015 | 43.1 | 34 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB. | 282 | Q63259 | 983 | PTPRN_RAT Receptor-type tyrosine-protein phos... | 59 | 0.016 | 43.1 | 34 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; TAS:RGD. | 283 | P35822 | 1457 | PTPRK_MOUSE Receptor-type tyrosine-protein ph... | 27 | 0.15 | 40 | 52 | 74 | GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 284 | Q60673 | 979 | PTPRN_MOUSE Receptor-type tyrosine-protein ph... | 59 | 0.014 | 43.5 | 34 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.::GO:0005886; C:plasma membrane; TAS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:MGI. | 285 | P29461 | 750 | PTP2_YEAST Tyrosine-protein phosphatase 2 OS=... | 40 | 0.0006 | 47.8 | 48 | 65 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0043937; P:regulation of sporulation; IGI:SGD. | 286 | O08617 | 656 | PTPRR_RAT Receptor-type tyrosine-protein phos... | 169 | 0.049 | 41.6 | 24 | 35 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD. | 287 | P54830 | 541 | PTN5_MOUSE Tyrosine-protein phosphatase non-r... | 33 | 0.3 | 38.9 | 45 | 58 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI. | | | | | | | | | | | 288 | P35234 | 369 | PTN5_RAT Tyrosine-protein phosphatase non-rec... | 62 | 0.64 | 37.4 | 32 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 289 | Q15256 | 657 | PTPRR_HUMAN Receptor-type tyrosine-protein ph... | 101 | 0.000000000001 | 75.9 | 43 | 56 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0001701; P:in utero embryonic development; IEP:UniProtKB. | 290 | Q5I146 | 325 | PTPH2_MDBVW Tyrosine phosphatase H2 OS=Microp... | 117 | 0.00003 | 51.2 | 31 | 43 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW. | 291 | Q62132 | 656 | PTPRR_MOUSE Receptor-type tyrosine-protein ph... | 169 | 0.04 | 41.6 | 24 | 35 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001701; P:in utero embryonic development; ISS:UniProtKB. | 292 | P54829 | 565 | PTN5_HUMAN Tyrosine-protein phosphatase non-r... | 106 | 0.14 | 40 | 30 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB. | | | | | | | | | | GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB. | | | | | | | | | | | 293 | Q5I128 | 318 | PTPN1_MDBVW Probable tyrosine phosphatase pro... | 95 | 0.00000000003 | 69.7 | 38 | 55 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 294 | B3DK56 | 1444 | PTPRU_DANRE Receptor-type tyrosine-protein ph... | 73 | 0.23 | 39.7 | 32 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001757; P:somite specification; IMP:ZFIN. | 295 | P25044 | 335 | PTP1_YEAST Tyrosine-protein phosphatase 1 OS=... | 63 | 0.55 | 37.7 | 38 | 51 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD. | 296 | P34138 | 377 | PTP2_DICDI Tyrosine-protein phosphatase 2 OS=... | 171 | 0.013 | 43.1 | 22 | 36 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:dictyBase. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase. | 297 | Q6PB44 | 1692 | PTN23_MOUSE Tyrosine-protein phosphatase non-... | 163 | 0.019 | 43.1 | 20 | 34 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB. | 298 | Q9H3S7 | 1636 | PTN23_HUMAN Tyrosine-protein phosphatase non-... | 163 | 0.003 | 45.8 | 21 | 34 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; IMP:UniProtKB. | 299 | O88902 | 1499 | PTN23_RAT Tyrosine-protein phosphatase non-re... | 114 | 0.018 | 43.1 | 22 | 35 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB. | 300 | Q24708 | 764 | CSW_DROVI Tyrosine-protein phosphatase corksc... | 121 | 0.0000006 | 57.4 | 29 | 40 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB. | 301 | Q92729 | 1446 | PTPRU_HUMAN Receptor-type tyrosine-protein ph... | 104 | 0.011 | 43.9 | 26 | 47 | GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; NAS:UniProtKB. |
