rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | Q87AX5 | 402 | C1331_XYLFT Putative cytochrome P450 133B1 OS... | 204 | 0.0008 | 45.8 | 25 | 37 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 542 | O73686 | 518 | CP192_CARAU Cytochrome P450 19 type 2 OS=Cara... | 208 | 0.0008 | 45.8 | 22 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 543 | Q9STL1 | 490 | C71AM_ARATH Cytochrome P450 71A22 OS=Arabidop... | 254 | 0.0009 | 45.8 | 22 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 544 | P15539 | 500 | C11B2_MOUSE Cytochrome P450 11B2, mitochondri... | 197 | 0.0009 | 45.8 | 26 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:MGI. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IDA:MGI.::GO:0042756; P:drinking behavior; IMP:MGI.::GO:0050801; P:ion homeostasis; IMP:MGI.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:MGI.::GO:0001991; P:regulation of systemic arterial blood pressure by circulatory renin-angiotensin; IMP:MGI. | 545 | Q6QHT9 | 511 | CP19A_ANGJA Cytochrome P450 19A1 OS=Anguilla ... | 194 | 0.0009 | 45.8 | 21 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 546 | P56594 | 487 | CP2CL_CANFA Cytochrome P450 2C21 OS=Canis fam... | 284 | 0.001 | 45.8 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 547 | P79430 | 503 | CP192_PIG Cytochrome P450 19 type II OS=Sus s... | 310 | 0.001 | 45.8 | 20 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 548 | P10614 | 530 | CP51_YEAST Lanosterol 14-alpha demethylase OS... | 235 | 0.001 | 45.4 | 22 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008398; F:sterol 14-demethylase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 549 | Q64403 | 500 | CP2DG_CAVPO Cytochrome P450 2D16 OS=Cavia por... | 221 | 0.001 | 45.4 | 25 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 550 | Q4V8D1 | 530 | CP2U1_RAT Cytochrome P450 2U1 OS=Rattus norve... | 203 | 0.001 | 45.4 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 551 | Q9CX98 | 530 | CP2U1_MOUSE Cytochrome P450 2U1 OS=Mus muscul... | 235 | 0.001 | 45.4 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 552 | O04790 | 510 | C75A7_EUSER Flavonoid 3',5'-hydroxylase OS=gr... | 270 | 0.001 | 45.1 | 25 | 37 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0033772; F:flavonoid 3',5'-hydroxylase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 553 | Q9VRB3 | 520 | CP6V1_DROME Probable cytochrome P450 6v1 OS=D... | 297 | 0.001 | 45.1 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 554 | P13108 | 500 | CP2D4_RAT Cytochrome P450 2D4 OS=Rattus norve... | 226 | 0.001 | 45.1 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 555 | Q9VGH1 | 520 | CP315_DROME Cytochrome P450 315a1, mitochondr... | 202 | 0.002 | 45.1 | 25 | 39 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042768; F:ecdysteroid 2-hydroxylase activity; IDA:FlyBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0006697; P:ecdysone biosynthetic process; IDA:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007494; P:midgut development; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase. | 556 | P12938 | 500 | CP2D3_RAT Cytochrome P450 2D3 OS=Rattus norve... | 224 | 0.002 | 44.7 | 23 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0001889; P:liver development; IEP:RGD. | 557 | Q9QUJ1 | 500 | CP2DS_MESAU Cytochrome P450 2D28 OS=Mesocrice... | 275 | 0.002 | 44.7 | 23 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | | 558 | Q9VMT5 | 502 | C28D1_DROME Probable cytochrome P450 28d1 OS=... | 219 | 0.002 | 44.7 | 25 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 559 | E1BHJ4 | 512 | CP26B_BOVIN Cytochrome P450 26B1 OS=Bos tauru... | 224 | 0.002 | 44.7 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 560 | P33265 | 490 | CP2CS_MESAU Cytochrome P450 2C28 OS=Mesocrice... | 321 | 0.002 | 44.7 | 22 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 561 | P19225 | 489 | CP270_RAT Cytochrome P450 2C70 OS=Rattus norv... | 207 | 0.002 | 44.7 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; NAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 562 | Q64658 | 500 | C11B2_MESAU Cytochrome P450 11B2, mitochondri... | 183 | 0.002 | 44.7 | 28 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 563 | Q9LJY7 | 510 | C75AK_ARATH Cytochrome P450 705A20 OS=Arabido... | 200 | 0.002 | 44.7 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 564 | P10635 | 497 | CP2D6_HUMAN Cytochrome P450 2D6 OS=Homo sapie... | 240 | 0.002 | 44.7 | 25 | 39 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0009804; P:coumarin metabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0033076; P:isoquinoline alkaloid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0051100; P:negative regulation of binding; IDA:BHF-UCL.::GO:0090350; P:negative regulation of cellular organofluorine metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL. | 565 | P79304 | 501 | CP193_PIG Cytochrome P450 19 type III OS=Sus ... | 271 | 0.002 | 44.7 | 21 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 566 | O08394 | 1061 | CYPD_BACSU Probable bifunctional P-450/NADPH-... | 204 | 0.002 | 44.7 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0010181; F:FMN binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0003958; F:NADPH-hemoprotein reductase activity; IEA:EC. | | | | | | | | | | GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 567 | P11511 | 503 | CP19A_HUMAN Cytochrome P450 19A1 OS=Homo sapi... | 315 | 0.002 | 44.3 | 21 | 39 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 568 | Q8CIM7 | 500 | CP2DQ_MOUSE Cytochrome P450 2D26 OS=Mus muscu... | 228 | 0.002 | 44.3 | 24 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 569 | P58049 | 496 | C71BB_ARATH Cytochrome P450 71B11 OS=Arabidop... | 218 | 0.003 | 44.3 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 570 | P10613 | 528 | CP51_CANAL Lanosterol 14-alpha demethylase OS... | 218 | 0.003 | 44.3 | 22 | 42 | GO:0016021; C:integral to membrane; IDA:CGD.::GO:0005624; C:membrane fraction; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD. | | | | | | | | | | GO:0008144; F:drug binding; IDA:CGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IDA:CGD. | | | | | | | | | | GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0006696; P:ergosterol biosynthetic process; IGI:CGD.::GO:0001766; P:membrane raft polarization; IMP:CGD. | 571 | Q27698 | 516 | CP6D1_MUSDO Cytochrome P450 6d1 OS=Musca dome... | 223 | 0.003 | 44.3 | 21 | 38 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |