rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q9UBF6 | 113 | RBX2_HUMAN RING-box protein 2 OS=Homo sapiens... | 60 | 0.064 | 37 | 32 | 45 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0005507; F:copper ion binding; TAS:ProtInc.::GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; TAS:ProtInc.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0051775; P:response to redox state; TAS:ProtInc. | 272 | O14686 | 5537 | MLL2_HUMAN Histone-lysine N-methyltransferase... | 54 | 0.069 | 39.7 | 37 | 48 | GO:0035097; C:histone methyltransferase complex; IPI:MGI. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0001555; P:oocyte growth; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 273 | O88196 | 1979 | TTC3_MOUSE E3 ubiquitin-protein ligase TTC3 O... | 90 | 0.07 | 39.7 | 27 | 42 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005773; C:vacuole; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010771; P:negative regulation of cell morphogenesis involved in differentiation; IDA:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 274 | Q8R079 | 450 | BFAR_MOUSE Bifunctional apoptosis regulator O... | 77 | 0.07 | 39.3 | 30 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 275 | P53804 | 2025 | TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 O... | 156 | 0.074 | 39.7 | 22 | 38 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 276 | Q7ZX20 | 540 | RNF8A_XENLA E3 ubiquitin-protein ligase RNF8-... | 103 | 0.081 | 39.3 | 24 | 41 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 277 | Q9M9L0 | 84 | APC11_ARATH Anaphase-promoting complex subuni... | 64 | 0.086 | 36.6 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 278 | A6NCQ9 | 220 | RN222_HUMAN RING finger protein 222 OS=Homo s... | 65 | 0.086 | 38.1 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 279 | Q9P0P0 | 153 | RN181_HUMAN E3 ubiquitin-protein ligase RNF18... | 48 | 0.088 | 37.4 | 35 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 280 | Q09251 | 409 | RN121_CAEEL RING finger protein 121 OS=Caenor... | 36 | 0.089 | 38.9 | 36 | 58 | GO:0000139; C:Golgi membrane; IDA:WormBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:WormBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:WormBase.::GO:0030433; P:ER-associated protein catabolic process; IMP:WormBase. | 281 | Q9LJL6 | 141 | ATL62_ARATH Putative RING-H2 finger protein A... | 46 | 0.094 | 37 | 37 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048577; P:negative regulation of short-day photoperiodism, flowering; IMP:TAIR. | 282 | P28284 | 825 | ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 O... | 72 | 0.099 | 38.9 | 29 | 40 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 283 | Q99MP8 | 591 | BRAP_MOUSE BRCA1-associated protein OS=Mus mu... | 59 | 0.1 | 38.9 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 284 | Q6PDK2 | 5588 | MLL2_MOUSE Histone-lysine N-methyltransferase... | 54 | 0.1 | 39.3 | 35 | 50 | | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IMP:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001555; P:oocyte growth; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 285 | Q3T0W3 | 153 | RN181_BOVIN E3 ubiquitin-protein ligase RNF18... | 48 | 0.1 | 37.4 | 35 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 286 | Q80XL1 | 496 | CBLC_MOUSE Signal transduction protein CBL-C ... | 52 | 0.11 | 38.5 | 35 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro. | 287 | Q3TTA7 | 982 | CBLB_MOUSE E3 ubiquitin-protein ligase CBL-B ... | 54 | 0.11 | 38.9 | 33 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006955; P:immune response; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045732; P:positive regulation of protein catabolic process; IMP:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0042110; P:T cell activation; IMP:MGI. | 288 | Q7Z569 | 592 | BRAP_HUMAN BRCA1-associated protein OS=Homo s... | 60 | 0.12 | 38.5 | 32 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000165; P:MAPK cascade; IDA:MGI.::GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:MGI. | 289 | Q8K4S7 | 938 | CBLB_RAT E3 ubiquitin-protein ligase CBL-B OS... | 54 | 0.12 | 38.9 | 33 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD. | 290 | Q13191 | 982 | CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B ... | 54 | 0.12 | 38.9 | 33 | 44 | | | | | | | | | | | | | | | | | | | | | | 291 | Q4TU14 | 371 | RHF1A_ARATH E3 ubiquitin-protein ligase RHF1A... | 46 | 0.13 | 38.1 | 37 | 57 | GO:0016020; C:membrane; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009561; P:megagametogenesis; IGI:TAIR.::GO:0055046; P:microgametogenesis; IGI:TAIR.::GO:0010498; P:proteasomal protein catabolic process; IDA:TAIR.::GO:0051726; P:regulation of cell cycle; IGI:TAIR. | 292 | Q09463 | 235 | RNF5_CAEEL RING finger protein 5 OS=Caenorhab... | 52 | 0.16 | 37.4 | 40 | 54 | GO:0030054; C:cell junction; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.::GO:0055002; P:striated muscle cell development; IMP:WormBase. | 293 | Q0IJ20 | 695 | RN145_XENTR RING finger protein 145 OS=Xenopu... | 54 | 0.16 | 38.1 | 35 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 294 | Q6CTZ8 | 427 | RAD18_KLULA Postreplication repair E3 ubiquit... | 47 | 0.17 | 38.1 | 38 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 295 | O74757 | 677 | HRD1_SCHPO ERAD-associated E3 ubiquitin-prote... | 98 | 0.17 | 38.1 | 30 | 44 | GO:0005938; C:cell cortex; IDA:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:PomBase.::GO:0010620; P:negative regulation of transcription by transcription factor catabolism; IMP:PomBase. | 296 | Q5BIY5 | 695 | RN145_XENLA RING finger protein 145 OS=Xenopu... | 65 | 0.17 | 38.1 | 32 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 297 | Q23457 | 110 | RBX1_CAEEL RING-box protein 1 OS=Caenorhabdit... | 58 | 0.18 | 35.8 | 34 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008595; P:anterior/posterior axis specification, embryo; IMP:WormBase.::GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007138; P:meiotic anaphase II; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0051759; P:sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation; IMP:WormBase. | 298 | Q8N4F7 | 328 | RN175_HUMAN RING finger protein 175 OS=Homo s... | 55 | 0.18 | 37.7 | 31 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 299 | Q54K33 | 104 | RBX1_DICDI RING-box protein 1 OS=Dictyosteliu... | 63 | 0.19 | 35.4 | 33 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 300 | Q6GQL0 | 918 | CBLBA_XENLA E3 ubiquitin-protein ligase CBL-B... | 54 | 0.19 | 38.1 | 33 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro. | 301 | Q54L48 | 87 | APC11_DICDI Anaphase-promoting complex subuni... | 51 | 0.19 | 35.4 | 33 | 51 | GO:0005680; C:anaphase-promoting complex; ISS:dictyBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase. |