| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | F1N6G5 | 909 | HACE1_BOVIN E3 ubiquitin-protein ligase HACE1... | 467 | 1e-35 | 150 | 28 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 62 | Q96PU5 | 975 | NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4... | 418 | 1e-35 | 150 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB. | 63 | Q5RBF2 | 959 | NED4L_PONAB E3 ubiquitin-protein ligase NEDD4... | 418 | 2e-35 | 150 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 64 | E1C656 | 942 | HACE1_CHICK E3 ubiquitin-protein ligase HACE1... | 467 | 2e-35 | 150 | 28 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 65 | Q2TAS2 | 751 | SMUF2_XENLA E3 ubiquitin-protein ligase SMURF... | 399 | 2e-35 | 149 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 66 | Q3U0D9 | 909 | HACE1_MOUSE E3 ubiquitin-protein ligase HACE1... | 465 | 3e-35 | 149 | 28 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 67 | Q8IYU2 | 909 | HACE1_HUMAN E3 ubiquitin-protein ligase HACE1... | 465 | 4e-35 | 149 | 28 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016601; P:Rac protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 68 | D3ZBM7 | 909 | HACE1_RAT E3 ubiquitin-protein ligase HACE1 O... | 465 | 7e-35 | 148 | 28 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 69 | O13834 | 3227 | PTR1_SCHPO E3 ubiquitin-protein ligase ptr1 O... | 438 | 2e-33 | 145 | 29 | 46 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. | | | | | | | | | | GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome. | 70 | Q9Y0H4 | 949 | SUDX_DROME E3 ubiquitin-protein ligase Su(dx)... | 409 | 2e-33 | 144 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0016348; P:imaginal disc-derived leg joint morphogenesis; IMP:UniProtKB.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IGI:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:UniProtKB.::GO:0019915; P:lipid storage; IDA:FlyBase.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.::GO:0007219; P:Notch signaling pathway; IGI:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0035209; P:pupal development; IMP:UniProtKB.::GO:0031623; P:receptor internalization; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:FlyBase.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IMP:UniProtKB. | 71 | Q9VVI3 | 1007 | NEDD4_DROME E3 ubiquitin-protein ligase Nedd-... | 396 | 3e-33 | 143 | 29 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB. | 72 | Q8RWB8 | 1029 | UPL6_ARATH E3 ubiquitin-protein ligase UPL6 O... | 485 | 5e-33 | 142 | 26 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro. | 73 | Q15386 | 1083 | UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=H... | 400 | 2e-29 | 131 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 74 | Q9SU29 | 873 | UPL5_ARATH E3 ubiquitin-protein ligase UPL5 O... | 397 | 7e-29 | 129 | 26 | 45 | GO:0005737; C:cytoplasm; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR. | | | | | | | | | | GO:0010150; P:leaf senescence; IMP:TAIR.::GO:0042542; P:response to hydrogen peroxide; IEP:UniProtKB.::GO:0009753; P:response to jasmonic acid stimulus; IEP:UniProtKB. | 75 | Q80U95 | 1083 | UBE3C_MOUSE Ubiquitin-protein ligase E3C OS=M... | 400 | 1e-28 | 128 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 76 | Q8CHG5 | 823 | K0317_MOUSE Protein KIAA0317 OS=Mus musculus ... | 399 | 5e-27 | 122 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 77 | O15033 | 823 | K0317_HUMAN Protein KIAA0317 OS=Homo sapiens ... | 399 | 7e-27 | 122 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 78 | Q9SCQ2 | 1142 | UPL7_ARATH E3 ubiquitin-protein ligase UPL7 O... | 407 | 5e-26 | 120 | 25 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro. | 79 | P53119 | 910 | HUL5_YEAST Probable E3 ubiquitin-protein liga... | 392 | 3e-24 | 114 | 28 | 43 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000502; C:proteasome complex; IDA:SGD. | | | | | | | | | | GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:SGD. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 80 | Q7Z3V4 | 1068 | UBE3B_HUMAN Ubiquitin-protein ligase E3B OS=H... | 421 | 9e-21 | 103 | 24 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 81 | Q9ES34 | 1070 | UBE3B_MOUSE Ubiquitin-protein ligase E3B OS=M... | 421 | 2e-20 | 102 | 24 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 82 | Q08CZ0 | 1072 | UBE3B_XENTR Ubiquitin-protein ligase E3B OS=X... | 421 | 2e-20 | 101 | 25 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro. | 83 | Q15751 | 4861 | HERC1_HUMAN Probable E3 ubiquitin-protein lig... | 382 | 8e-17 | 90.9 | 25 | 42 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 84 | P51592 | 2885 | HYD_DROME E3 ubiquitin-protein ligase hyd OS=... | 320 | 0.000000000001 | 77 | 27 | 43 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048749; P:compound eye development; NAS:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0007112; P:male meiosis cytokinesis; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; NAS:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0030162; P:regulation of proteolysis; NAS:FlyBase.::GO:0007289; P:spermatid nucleus differentiation; IMP:FlyBase. | 85 | Q14669 | 1992 | TRIPC_HUMAN Probable E3 ubiquitin-protein lig... | 428 | 0.000000000008 | 74.3 | 25 | 39 | GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 86 | Q9LYZ7 | 1502 | UPL4_ARATH E3 ubiquitin-protein ligase UPL4 O... | 318 | 0.00000000002 | 72.8 | 25 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro. | 87 | Q10435 | 1647 | YDE1_SCHPO Probable ubiquitin fusion degradat... | 313 | 0.00000000009 | 70.9 | 25 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome. | 88 | Q62671 | 2788 | UBR5_RAT E3 ubiquitin-protein ligase UBR5 OS=... | 306 | 0.0000000004 | 68.6 | 24 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 89 | O95071 | 2799 | UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 O... | 306 | 0.000000001 | 67 | 24 | 40 | GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:BHF-UCL.::GO:0050847; P:progesterone receptor signaling pathway; IDA:HGNC.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IDA:HGNC. | 90 | Q80TP3 | 2792 | UBR5_MOUSE E3 ubiquitin-protein ligase UBR5 O... | 306 | 0.000000001 | 67 | 24 | 40 | GO:0005634; C:nucleus; ISS:HGNC. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0050847; P:progesterone receptor signaling pathway; ISS:HGNC.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; ISS:HGNC. | 91 | Q4U2R1 | 4836 | HERC2_MOUSE E3 ubiquitin-protein ligase HERC2... | 367 | 0.000000008 | 64.3 | 25 | 38 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI. |
