rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9Y7Q7 | 973 | DENN_SCHPO DENN domain-containing protein C29... | 173 | 0.000000004 | 64.3 | 24 | 48 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | | 2 | Q6PAL8 | 1287 | DEN5A_MOUSE DENN domain-containing protein 5A... | 421 | 4e-18 | 94 | 25 | 42 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IDA:MGI. | | | | | | | | | | | 3 | Q6ZUT9 | 1274 | DEN5B_HUMAN DENN domain-containing protein 5B... | 468 | 5e-18 | 94 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 4 | A2RSQ0 | 1274 | DEN5B_MOUSE DENN domain-containing protein 5B... | 468 | 2e-17 | 92 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 5 | O95248 | 1867 | MTMR5_HUMAN Myotubularin-related protein 5 OS... | 152 | 2e-16 | 88.2 | 34 | 60 | GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; TAS:UniProtKB. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; TAS:UniProtKB. | 6 | Q6ZPE2 | 1867 | MTMR5_MOUSE Myotubularin-related protein 5 OS... | 152 | 7e-16 | 87 | 33 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016791; F:phosphatase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0001691; F:pseudophosphatase activity; TAS:MGI. | | | | | | | | | | GO:0001558; P:regulation of cell growth; TAS:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 7 | Q86WG5 | 1849 | MTMRD_HUMAN Myotubularin-related protein 13 O... | 152 | 0.00000000000002 | 82.4 | 33 | 57 | | | | | | | | | | | GO:0016791; F:phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0042552; P:myelination; NAS:UniProtKB. | 8 | Q6NXD8 | 1311 | DEN5B_DANRE DENN domain-containing protein 5B... | 155 | 0.00000000000002 | 82 | 33 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 9 | Q91VV4 | 469 | DEN2D_MOUSE DENN domain-containing protein 2D... | 67 | 4.5 | 34.7 | 28 | 51 | | | | | | | | | | | | | | | | | | | | | | 10 | P78524 | 1137 | ST5_HUMAN Suppression of tumorigenicity 5 pro... | 132 | 0.00000000000003 | 81.6 | 35 | 54 | | | | | | | | | | | | | | | | | | | | | GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:MGI. | 11 | Q924W7 | 1134 | ST5_MOUSE Suppression of tumorigenicity 5 pro... | 132 | 0.00000000000003 | 81.3 | 35 | 54 | | | | | | | | | | | | | | | | | | | | | | 12 | Q9H6A0 | 471 | DEN2D_HUMAN DENN domain-containing protein 2D... | 106 | 0.00000000000003 | 80.1 | 36 | 59 | | | | | | | | | | | | | | | | | | | | | | 13 | Q6NTN5 | 1873 | MTMRD_XENLA Myotubularin-related protein 13 O... | 152 | 0.0000000000001 | 79.3 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016791; F:phosphatase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 14 | Q6IQ26 | 1287 | DEN5A_HUMAN DENN domain-containing protein 5A... | 107 | 0.015 | 43.1 | 27 | 45 | | | | | | | | | | | | | | | | | | | | | | 15 | O75064 | 1496 | DEN4B_HUMAN DENN domain-containing protein 4B... | 86 | 0.74 | 37.7 | 29 | 45 | | | | | | | | | | | | | | | | | | | | | | 16 | Q7Z401 | 1863 | MYCPP_HUMAN C-myc promoter-binding protein OS... | 99 | 0.000000000001 | 76.6 | 37 | 59 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; NAS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q68D51 | 928 | DEN2C_HUMAN DENN domain-containing protein 2C... | 130 | 0.000000000006 | 73.6 | 32 | 56 | | | | | | | | | | | | | | | | | | | | | | 18 | Q5VZ89 | 1673 | DEN4C_HUMAN DENN domain-containing protein 4C... | 90 | 0.01 | 43.9 | 30 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 19 | Q8TEH3 | 1009 | DEN1A_HUMAN DENN domain-containing protein 1A... | 117 | 0.00000000001 | 73.2 | 32 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | Q8K382 | 1016 | DEN1A_MOUSE DENN domain-containing protein 1A... | 117 | 0.00000000001 | 72.8 | 32 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030665; C:clathrin coated vesicle membrane; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:MGI. | | | | | | | | | | GO:0048488; P:synaptic vesicle endocytosis; IDA:MGI. | 21 | Q6P9P8 | 914 | DEN2C_MOUSE DENN domain-containing protein 2C... | 104 | 0.00000000002 | 72 | 34 | 58 | | | | | | | | | | | | | | | | | | | | | | 22 | Q6P3S1 | 426 | DEN1B_HUMAN DENN domain-containing protein 1B... | 116 | 0.00000000002 | 70.9 | 33 | 58 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 23 | Q8IV53 | 801 | DEN1C_HUMAN DENN domain-containing protein 1C... | 110 | 0.00000000003 | 71.2 | 33 | 55 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q3U1Y4 | 1499 | DEN4B_MOUSE DENN domain-containing protein 4B... | 86 | 0.37 | 38.5 | 29 | 45 | | | | | | | | | | | | | | | | | | | | | | 25 | Q3U1T9 | 425 | DEN1B_MOUSE DENN domain-containing protein 1B... | 116 | 0.00000000007 | 69.3 | 34 | 57 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q9ULE3 | 1009 | DEN2A_HUMAN DENN domain-containing protein 2A... | 76 | 0.0000000001 | 69.7 | 36 | 62 | | | | | | | | | | | | | | | | | | | | | | 27 | Q8C4S8 | 1000 | DEN2A_MOUSE DENN domain-containing protein 2A... | 76 | 0.0000000002 | 68.9 | 36 | 62 | | | | | | | | | | | | | | | | | | | | | | 28 | Q8CFK6 | 786 | DEN1C_MOUSE DENN domain-containing protein 1C... | 108 | 0.0000000003 | 68.2 | 32 | 55 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 29 | Q68F67 | 1010 | DEN1A_XENLA DENN domain-containing protein 1A... | 117 | 0.0000000006 | 67.4 | 30 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | A2RT67 | 1274 | DEND3_MOUSE DENN domain-containing protein 3 ... | 104 | 0.000000003 | 64.7 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | | 31 | Q9VXY2 | 2075 | MADD_DROME MAP kinase-activating death domain... | 105 | 0.00000004 | 61.2 | 32 | 57 | GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; NAS:FlyBase. | | | | | | | | | | GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; NAS:FlyBase. |