rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P10829 | 697 | KPCG_RABIT Protein kinase C gamma type OS=Ory... | 104 | 0.024 | 42.4 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 62 | P21707 | 421 | SYT1_RAT Synaptotagmin-1 OS=Rattus norvegicus... | 91 | 0.025 | 42.4 | 32 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0031045; C:dense core granule; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; TAS:RGD.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:RGD.::GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD. | 63 | P46096 | 421 | SYT1_MOUSE Synaptotagmin-1 OS=Mus musculus (M... | 91 | 0.025 | 42.4 | 32 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:UniProtKB.::GO:0042734; C:presynaptic membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005544; F:calcium-dependent phospholipid binding; TAS:MGI.::GO:0048306; F:calcium-dependent protein binding; IPI:HGNC.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; IMP:MGI. | 64 | Q4R4U2 | 697 | KPCG_MACFA Protein kinase C gamma type OS=Mac... | 104 | 0.026 | 42.4 | 30 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 65 | P21521 | 474 | SY65_DROME Synaptotagmin 1 OS=Drosophila mela... | 71 | 0.027 | 42.4 | 31 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030285; C:integral to synaptic vesicle membrane; NAS:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; TAS:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IMP:FlyBase.::GO:0008345; P:larval locomotory behavior; IMP:FlyBase.::GO:0007317; P:regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IDA:FlyBase. | 66 | P20444 | 672 | KPCA_MOUSE Protein kinase C alpha type OS=Mus... | 84 | 0.053 | 41.2 | 31 | 56 | GO:0030425; C:dendrite; IDA:MGI.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0002062; P:chondrocyte differentiation; IDA:MGI.::GO:0000188; P:inactivation of MAPK activity; IMP:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0050930; P:induction of positive chemotaxis; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0046325; P:negative regulation of glucose import; IMP:MGI.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:MGI.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0030593; P:neutrophil chemotaxis; IMP:MGI.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; IMP:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050729; P:positive regulation of inflammatory response; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0006937; P:regulation of muscle contraction; IMP:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:MGI. | 67 | P63319 | 697 | KPCG_RAT Protein kinase C gamma type OS=Rattu... | 104 | 0.069 | 41.2 | 29 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0007611; P:learning or memory; IEP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:RGD. | 68 | P63318 | 697 | KPCG_MOUSE Protein kinase C gamma type OS=Mus... | 104 | 0.069 | 41.2 | 29 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0097060; C:synaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007635; P:chemosensory behavior; IMP:MGI.::GO:0060384; P:innervation; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; IMP:UniProtKB.::GO:0048265; P:response to pain; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB. | 69 | Q9R0N6 | 395 | SYT8_MOUSE Synaptotagmin-8 OS=Mus musculus (M... | 71 | 0.074 | 40.4 | 34 | 58 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031988; C:membrane-bounded vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0007340; P:acrosome reaction; IDA:HGNC. | 70 | A9Z1Z3 | 1794 | FR1L4_HUMAN Fer-1-like protein 4 OS=Homo sapi... | 92 | 0.082 | 41.2 | 28 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 71 | B2RUP2 | 1085 | UN13D_MOUSE Protein unc-13 homolog D OS=Mus m... | 95 | 0.091 | 40.8 | 33 | 49 | GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:MGI.::GO:0002467; P:germinal center formation; IMP:MGI.::GO:0002432; P:granuloma formation; IMP:MGI.::GO:0043320; P:natural killer cell degranulation; IMP:MGI.::GO:0006909; P:phagocytosis; IMP:MGI. | 72 | Q69ZN7 | 2048 | MYOF_MOUSE Myoferlin OS=Mus musculus (Mouse).... | 110 | 0.097 | 40.8 | 25 | 54 | GO:0005901; C:caveola; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IMP:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0001778; P:plasma membrane repair; IMP:UniProtKB.::GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB. | 73 | P10102 | 672 | KPCA_RABIT Protein kinase C alpha type OS=Ory... | 84 | 0.12 | 40.4 | 31 | 55 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB. | 74 | P05696 | 672 | KPCA_RAT Protein kinase C alpha type OS=Rattu... | 84 | 0.12 | 40.4 | 31 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:RGD.::GO:0045184; P:establishment of protein localization; TAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0017148; P:negative regulation of translation; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IDA:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:RGD.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0051965; P:positive regulation of synapse assembly; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0048259; P:regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0046677; P:response to antibiotic; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IMP:RGD.::GO:0045471; P:response to ethanol; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; IMP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 75 | Q920N7 | 421 | SYT12_MOUSE Synaptotagmin-12 OS=Mus musculus ... | 185 | 0.12 | 40 | 24 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 76 | P17252 | 672 | KPCA_HUMAN Protein kinase C alpha type OS=Hom... | 84 | 0.12 | 40 | 31 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0090330; P:regulation of platelet aggregation; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 77 | Q50L43 | 825 | PA24D_MOUSE Cytosolic phospholipase A2 delta ... | 126 | 0.13 | 40.4 | 22 | 47 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IDA:MGI. | | | | | | | | | | GO:0009395; P:phospholipid catabolic process; IEA:InterPro. | 78 | P90980 | 682 | KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh... | 101 | 0.13 | 40 | 33 | 52 | GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 79 | Q5RJH2 | 878 | MCTP2_MOUSE Multiple C2 and transmembrane dom... | 86 | 0.15 | 40 | 31 | 57 | GO:0016021; C:integral to membrane; ISS:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:HGNC. | | | | | | | | | | | 80 | Q9UPW8 | 1703 | UN13A_HUMAN Protein unc-13 homolog A OS=Homo ... | 109 | 0.2 | 39.7 | 27 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 81 | Q4KUS2 | 1712 | UN13A_MOUSE Protein unc-13 homolog A OS=Mus m... | 109 | 0.2 | 39.7 | 27 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019992; F:diacylglycerol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI. | 82 | Q16974 | 649 | KPC1_APLCA Calcium-dependent protein kinase C... | 50 | 0.23 | 39.3 | 42 | 68 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 83 | Q9R0N7 | 403 | SYT7_MOUSE Synaptotagmin-7 OS=Mus musculus (M... | 98 | 1.4 | 36.6 | 28 | 51 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0001778; P:plasma membrane repair; IDA:MGI. | 84 | P97610 | 421 | SYT12_RAT Synaptotagmin-12 OS=Rattus norvegic... | 185 | 0.33 | 38.5 | 25 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0046928; P:regulation of neurotransmitter secretion; NAS:RGD. | 85 | Q0JHU5 | 159 | ERG1_ORYSJ Elicitor-responsive protein 1 OS=O... | 130 | 0.34 | 37 | 27 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | A2WWV5 | 159 | ERG1_ORYSI Elicitor-responsive protein 1 OS=O... | 130 | 0.34 | 37 | 27 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW. | | | | | | | | | | | 87 | Q9R189 | 1088 | UN13D_RAT Protein unc-13 homolog D OS=Rattus ... | 95 | 0.35 | 38.9 | 31 | 48 | GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 88 | Q62769 | 1622 | UN13B_RAT Protein unc-13 homolog B OS=Rattus ... | 109 | 0.42 | 38.5 | 27 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 89 | Q9Z1N9 | 1602 | UN13B_MOUSE Protein unc-13 homolog B OS=Mus m... | 109 | 0.43 | 38.5 | 27 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001566; F:non-kinase phorbol ester receptor activity; TAS:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI. | 90 | Q86XP0 | 818 | PA24D_HUMAN Cytosolic phospholipase A2 delta ... | 124 | 0.44 | 38.5 | 23 | 45 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IEA:EC. | | | | | | | | | | GO:0009395; P:phospholipid catabolic process; IEA:InterPro. | 91 | O43052 | 1150 | RGA1_SCHPO Rho-type GTPase-activating protein... | 72 | 0.45 | 38.5 | 35 | 50 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. |