Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Magnaporthe oryzae 70-15 (MG8)
Locus:
MGG_01076
Length:
758
Number of sequences:
12991
Description:
histone deacetylase HDA1
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P56523    687   CLR3_SCHPO Histone deacetylase clr3 OS=Schizo...6656e-167     504     41     59GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0031934; C:mating-type region heterochromatin; IDA:PomBase.::GO:0030874; C:nucleolar chromatin; IDA:PomBase.::GO:0016581; C:NuRD complex; IDA:PomBase.::GO:0033553; C:rDNA heterochromatin; IDA:PomBase.::GO:0031933; C:telomeric heterochromatin; IDA:PomBase.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0000183; P:chromatin silencing at rDNA; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0035391; P:maintenance of chromatin silencing at silent mating-type cassette; NAS:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:PomBase.::GO:0016584; P:nucleosome positioning; IMP:PomBase.::GO:0031060; P:regulation of histone methylation; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2P53973    706   HDA1_YEAST Histone deacetylase HDA1 OS=Saccha...6721e-154     473     39     58GO:0070823; C:HDA1 complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0031047; P:gene silencing by RNA; IMP:SGD.::GO:0010978; P:gene silencing involved in chronological cell aging; IMP:SGD.::GO:0001308; P:negative regulation of chromatin silencing involved in replicative cell aging; IMP:SGD.::GO:0010621; P:negative regulation of transcription by transcription factor localization; IGI:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q9Z2V5    1149   HDAC6_MOUSE Histone deacetylase 6 OS=Mus musc...3677e-68     247     37     56GO:0005881; C:cytoplasmic microtubule; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; IDA:MGI.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070842; P:aggresome assembly; IGI:MGI.::GO:0071218; P:cellular response to misfolded protein; IMP:MGI.::GO:0070846; P:Hsp90 deacetylation; IMP:MGI.::GO:0007026; P:negative regulation of microtubule depolymerization; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0090042; P:tubulin deacetylation; IDA:UniProtKB.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:MGI.
4Q9UBN7    1215   HDAC6_HUMAN Histone deacetylase 6 OS=Homo sap...4062e-66     243     35     54GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0031252; C:cell leading edge; IDA:BHF-UCL.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; IDA:UniProtKB.::GO:0005875; C:microtubule associated complex; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0070840; F:dynein complex binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:BHF-UCL.::GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:BHF-UCL.::GO:0070846; P:Hsp90 deacetylation; IMP:BHF-UCL.::GO:0032418; P:lysosome localization; IMP:BHF-UCL.::GO:0016236; P:macroautophagy; IMP:BHF-UCL.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:BHF-UCL.::GO:0010727; P:negative regulation of hydrogen peroxide metabolic process; IC:BHF-UCL.::GO:0051354; P:negative regulation of oxidoreductase activity; IC:BHF-UCL.::GO:0045861; P:negative regulation of proteolysis; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0034983; P:peptidyl-lysine deacetylation; IMP:BHF-UCL.::GO:0070845; P:polyubiquitinated misfolded protein transport; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0090035; P:positive regulation of chaperone-mediated protein complex assembly; IMP:BHF-UCL.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:BHF-UCL.::GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.::GO:0009967; P:positive regulation of signal transduction; IMP:BHF-UCL.::GO:0060765; P:regulation of androgen receptor signaling pathway; TAS:BHF-UCL.::GO:0060632; P:regulation of microtubule-based movement; IC:BHF-UCL.::GO:0010469; P:regulation of receptor activity; IMP:BHF-UCL.::GO:0070848; P:response to growth factor stimulus; IMP:BHF-UCL.::GO:0009636; P:response to toxin; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0090042; P:tubulin deacetylation; ISS:UniProtKB.
5Q8RX28    660   HDA5_ARATH Histone deacetylase 5 OS=Arabidops...3528e-80     275     41     59GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q8LRK8    682   HDA18_ARATH Histone deacetylase 18 OS=Arabido...4052e-79     274     37     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0045604; P:regulation of epidermal cell differentiation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q6P3E7    666   HDA10_MOUSE Histone deacetylase 10 OS=Mus mus...3291e-78     271     41     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q969S8    669   HDA10_HUMAN Histone deacetylase 10 OS=Homo sa...1270.0003     48.1     31     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000118; C:histone deacetylase complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0004407; F:histone deacetylase activity; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q80ZH1    1111   HDAC5_CRIGR Histone deacetylase 5 OS=Cricetul...4244e-74     265     38     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; IEA:InterPro.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q20296    955   HDA6_CAEEL Histone deacetylase 6 OS=Caenorhab...3704e-51     196     34     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q99P99    1077   HDAC4_RAT Histone deacetylase 4 OS=Rattus nor...4373e-72     259     38     53GO:0031672; C:A band; IDA:MGI.::GO:0030018; C:Z disc; IDA:MGI.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0042493; P:response to drug; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12P56524    1084   HDAC4_HUMAN Histone deacetylase 4 OS=Homo sap...4114e-72     259     37     54GO:0000118; C:histone deacetylase complex; IDA:BHF-UCL.::GO:0017053; C:transcriptional repressor complex; IDA:BHF-UCL.
GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0030955; F:potassium ion binding; IDA:BHF-UCL.::GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
GO:0030183; P:B cell differentiation; TAS:UniProtKB.::GO:0014898; P:cardiac muscle hypertrophy in response to stress; TAS:BHF-UCL.::GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.::GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.::GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045820; P:negative regulation of glycolysis; ISS:BHF-UCL.::GO:0010832; P:negative regulation of myotube differentiation; IMP:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007399; P:nervous system development; TAS:UniProtKB.::GO:0034983; P:peptidyl-lysine deacetylation; IDA:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043393; P:regulation of protein binding; IMP:BHF-UCL.::GO:0014894; P:response to denervation involved in regulation of muscle adaptation; ISS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q6NZM9    1076   HDAC4_MOUSE Histone deacetylase 4 OS=Mus musc...4377e-72     258     37     53GO:0042641; C:actomyosin; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IGI:MGI.
GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.::GO:0045820; P:negative regulation of glycolysis; IMP:BHF-UCL.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0002076; P:osteoblast development; IMP:MGI.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0010882; P:regulation of cardiac muscle contraction by calcium ion signaling; IMP:MGI.::GO:0014894; P:response to denervation involved in regulation of muscle adaptation; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q8GXJ1    552   HDA15_ARATH Histone deacetylase 15 OS=Arabido...3502e-71     249     44     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q8WUI4    952   HDAC7_HUMAN Histone deacetylase 7 OS=Homo sap...4172e-70     254     38     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000118; C:histone deacetylase complex; IEA:InterPro.
GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
GO:0032703; P:negative regulation of interleukin-2 production; IDA:BHF-UCL.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q8C2B3    938   HDAC7_MOUSE Histone deacetylase 7 OS=Mus musc...4161e-69     251     38     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0030183; P:B cell differentiation; TAS:UniProtKB.::GO:0007043; P:cell-cell junction assembly; IMP:MGI.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045843; P:negative regulation of striated muscle tissue development; TAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007399; P:nervous system development; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001570; P:vasculogenesis; IMP:MGI.
17P83038    1080   HDAC4_CHICK Histone deacetylase 4 OS=Gallus g...4112e-69     251     37     53GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0008134; F:transcription factor binding; TAS:UniProtKB.
GO:0030183; P:B cell differentiation; TAS:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045843; P:negative regulation of striated muscle tissue development; TAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q9UKV0    1011   HDAC9_HUMAN Histone deacetylase 9 OS=Homo sap...3736e-69     249     40     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.::GO:0035097; C:histone methyltransferase complex; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0070491; F:repressing transcription factor binding; IDA:BHF-UCL.::GO:0003714; F:transcription corepressor activity; ISS:BHF-UCL.
GO:0030183; P:B cell differentiation; TAS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0007507; P:heart development; ISS:BHF-UCL.::GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.::GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0034983; P:peptidyl-lysine deacetylation; IDA:BHF-UCL.::GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:0048742; P:regulation of skeletal muscle fiber development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q613L4    892   HDA4_CAEBR Histone deacetylase 4 OS=Caenorhab...4221e-68     248     36     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q9UQL6    1122   HDAC5_HUMAN Histone deacetylase 5 OS=Homo sap...4221e-68     249     38     53GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
GO:0030183; P:B cell differentiation; TAS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; NAS:BHF-UCL.::GO:0006338; P:chromatin remodeling; TAS:ProtInc.::GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:0010832; P:negative regulation of myotube differentiation; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043393; P:regulation of protein binding; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q5R902    1122   HDAC5_PONAB Histone deacetylase 5 OS=Pongo ab...4221e-67     246     38     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0000118; C:histone deacetylase complex; IEA:InterPro.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22O17323    816   HDA4_CAEEL Histone deacetylase 4 OS=Caenorhab...4052e-67     243     36     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q9Z2V6    1113   HDAC5_MOUSE Histone deacetylase 5 OS=Mus musc...4296e-67     244     37     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000118; C:histone deacetylase complex; TAS:UniProtKB.
GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:UniProtKB.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
GO:0030183; P:B cell differentiation; TAS:UniProtKB.::GO:0071498; P:cellular response to fluid shear stress; IDA:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045843; P:negative regulation of striated muscle tissue development; TAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:UniProtKB.::GO:2000179; P:positive regulation of neural precursor cell proliferation; IMP:BHF-UCL.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:BHF-UCL.::GO:0010830; P:regulation of myotube differentiation; IDA:UniProtKB.::GO:0061333; P:renal tubule morphogenesis; IMP:UniProtKB.
24Q569C4    588   HDA10_RAT Histone deacetylase 10 OS=Rattus no...1275.2     34.3     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q941D6    423   HDA14_ARATH Histone deacetylase 14 OS=Arabido...3576e-44     168     34     49GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q70I53    369   HDAH_ALCSD Histone deacetylase-like amidohydr...3024e-43     164     34     52
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
27O30107    359   Y130_ARCFU Uncharacterized protein AF_0130 OS...4121e-37     149     29     46
GO:0004407; F:histone deacetylase activity; IEA:InterPro.
28O27262    331   Y1194_METTH Uncharacterized protein MTH_1194 ...3107e-35     140     31     49
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
29Q94EJ2    377   HDA8_ARATH Histone deacetylase 8 OS=Arabidops...3743e-32     133     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:EC.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:EC.::GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30P72702    304   Y245_SYNY3 Uncharacterized protein slr0245 OS...3371e-30     127     29     48
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
31Q57955    343   Y535_METJA Uncharacterized protein MJ0535 OS=...3021e-28     122     31     48
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
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