| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q3UZY0 | 1216 | SFI1_MOUSE Protein SFI1 homolog OS=Mus muscul... | 74 | 0.001 | 43.5 | 36 | 46 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 2 | B0KWR6 | 1235 | SFI1_CALJA Protein SFI1 homolog OS=Callithrix... | 133 | 0.002 | 42.7 | 29 | 38 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 3 | A2AL36 | 2334 | CNTRL_MOUSE Centriolin OS=Mus musculus (Mouse... | 125 | 0.004 | 42 | 29 | 36 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 4 | Q14524 | 2016 | SCN5A_HUMAN Sodium channel protein type 5 sub... | 130 | 0.022 | 39.7 | 29 | 42 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0042383; C:sarcolemma; IDA:BHF-UCL.::GO:0001518; C:voltage-gated sodium channel complex; IC:BHF-UCL. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0008015; P:blood circulation; NAS:ProtInc.::GO:0061337; P:cardiac conduction; IMP:BHF-UCL.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0045760; P:positive regulation of action potential; IDA:BHF-UCL.::GO:0060452; P:positive regulation of cardiac muscle contraction; IMP:BHF-UCL.::GO:0060371; P:regulation of atrial cardiomyocyte membrane depolarization; TAS:BHF-UCL.::GO:0060372; P:regulation of atrial cardiomyocyte membrane repolarization; TAS:BHF-UCL.::GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.::GO:0060373; P:regulation of ventricular cardiomyocyte membrane depolarization; TAS:BHF-UCL.::GO:0060307; P:regulation of ventricular cardiomyocyte membrane repolarization; TAS:BHF-UCL. | 5 | Q9VJE5 | 1690 | CL190_DROME Restin homolog OS=Drosophila mela... | 102 | 0.025 | 39.3 | 30 | 39 | GO:0045169; C:fusome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005875; C:microtubule associated complex; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB. | | | | | | | | | | GO:0007349; P:cellularization; IMP:UniProtKB. | 6 | P19754 | 1134 | ADCY1_BOVIN Adenylate cyclase type 1 OS=Bos t... | 40 | 0.033 | 38.9 | 50 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 7 | Q9VDW3 | 1669 | DMDB_DROME Dystrophin, isoform B OS=Drosophil... | 67 | 0.042 | 38.5 | 37 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 8 | O75962 | 3097 | TRIO_HUMAN Triple functional domain protein O... | 159 | 0.059 | 38.1 | 25 | 34 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 9 | Q9JJV9 | 2019 | SCN5A_MOUSE Sodium channel protein type 5 sub... | 158 | 0.25 | 36.2 | 27 | 37 | GO:0014704; C:intercalated disc; IDA:MGI.::GO:0030315; C:T-tubule; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IC:MGI. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB. | 10 | P15389 | 2019 | SCN5A_RAT Sodium channel protein type 5 subun... | 158 | 0.31 | 35.8 | 27 | 39 | GO:0001518; C:voltage-gated sodium channel complex; TAS:RGD. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB. | 11 | P25439 | 1638 | BRM_DROME ATP-dependent helicase brm OS=Droso... | 65 | 0.57 | 35 | 35 | 40 | GO:0035060; C:brahma complex; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043044; P:ATP-dependent chromatin remodeling; IDA:FlyBase.::GO:0007409; P:axonogenesis; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0035172; P:hemocyte proliferation; TAS:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IGI:FlyBase.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IGI:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q25060 | 419 | LWA_HYDEC LWamide neuropeptides OS=Hydractini... | 101 | 1.1 | 33.9 | 40 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW. | 13 | Q6IQ32 | 1131 | ADNP2_HUMAN ADNP homeobox protein 2 OS=Homo s... | 87 | 1.8 | 33.5 | 36 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q9VMA7 | 1430 | TGO1_DROME Transport and Golgi organization p... | 48 | 2 | 33.5 | 44 | 50 | GO:0070971; C:endoplasmic reticulum exit site; IDA:FlyBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0009306; P:protein secretion; IMP:UniProtKB. | 15 | Q13459 | 2157 | MYO9B_HUMAN Unconventional myosin-IXb OS=Homo... | 103 | 2.3 | 33.1 | 29 | 35 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB. | | | | | | | | | | GO:0030048; P:actin filament-based movement; TAS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; IC:UniProtKB. | 16 | Q8BZ98 | 863 | DYN3_MOUSE Dynamin-3 OS=Mus musculus (Mouse).... | 88 | 2.3 | 33.1 | 34 | 38 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 17 | Q11PK5 | 1008 | IF2_CYTH3 Translation initiation factor IF-2 ... | 69 | 3 | 32.7 | 39 | 43 | GO:0005840; C:ribosome; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q9UKF5 | 820 | ADA29_HUMAN Disintegrin and metalloproteinase... | 99 | 3.9 | 32.3 | 27 | 35 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro.::GO:0007283; P:spermatogenesis; TAS:ProtInc. | 19 | Q5JRA6 | 1907 | MIA3_HUMAN Melanoma inhibitory activity prote... | 173 | 4 | 32.3 | 32 | 36 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006887; P:exocytosis; IMP:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; IDA:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.::GO:0002687; P:positive regulation of leukocyte migration; IDA:BHF-UCL.::GO:0015031; P:protein transport; IMP:UniProtKB.::GO:0042060; P:wound healing; IDA:BHF-UCL. | 20 | Q8IU68 | 726 | TMC8_HUMAN Transmembrane channel-like protein... | 61 | 4.7 | 32 | 38 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 21 | B2HNQ9 | 454 | ESPB_MYCMM ESX-1 secretion-associated protein... | 88 | 6.9 | 31.6 | 34 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 22 | Q8C9B9 | 2256 | DIDO1_MOUSE Death-inducer obliterator 1 OS=Mu... | 99 | 8.7 | 31.6 | 36 | 41 | GO:0005737; C:cytoplasm; TAS:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. | 23 | A2BT70 | 1126 | IF2_PROMS Translation initiation factor IF-2 ... | 83 | 9.6 | 31.2 | 37 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | |
