| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q01294 | 396 | CARP_NEUCR Vacuolar protease A OS=1257 / FGSC... | 395 | 0 | 620 | 73 | 85 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | O42630 | 398 | CARP_ASPFU Vacuolar protease A OS=A1100) (Asp... | 395 | 0 | 583 | 69 | 83 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | D4DEN7 | 400 | CARP_TRIVH Probable vacuolar protease A OS=Tr... | 383 | 0 | 552 | 67 | 81 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | D4B385 | 400 | CARP_ARTBC Probable vacuolar protease A OS=(T... | 385 | 0 | 548 | 66 | 80 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 5 | C5FS55 | 395 | CARP_ARTOC Vacuolar protease A OS=canis). GN=... | 383 | 0 | 533 | 66 | 80 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | P07267 | 405 | CARP_YEAST Saccharopepsin OS=Saccharomyces ce... | 383 | 4e-169 | 486 | 59 | 75 | GO:0000328; C:fungal-type vacuole lumen; TAS:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009267; P:cellular response to starvation; IMP:SGD.::GO:0016237; P:microautophagy; IMP:SGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:SGD. | 7 | P10977 | 419 | CARPV_CANAX Vacuolar aspartic protease OS=Can... | 412 | 4e-156 | 454 | 54 | 68 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 8 | Q03168 | 387 | ASPP_AEDAE Lysosomal aspartic protease OS=Aed... | 336 | 3e-105 | 322 | 48 | 64 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 9 | Q05744 | 398 | CATD_CHICK Cathepsin D OS=Gallus gallus (Chic... | 334 | 4e-97 | 302 | 46 | 64 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | O93428 | 396 | CATD_CHIHA Cathepsin D OS=rhinoceratus hamatu... | 338 | 2e-96 | 300 | 45 | 64 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IDA:UniProtKB. | 11 | O09043 | 419 | NAPSA_MOUSE Napsin-A OS=Mus musculus (Mouse).... | 379 | 5e-96 | 300 | 42 | 59 | GO:0042599; C:lamellar body; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IMP:UniProtKB. | 12 | P07339 | 412 | CATD_HUMAN Cathepsin D OS=Homo sapiens (Human... | 354 | 2e-95 | 298 | 44 | 61 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | Q9DEX3 | 396 | CATD_CLUHA Cathepsin D OS=Clupea harengus (At... | 337 | 2e-93 | 292 | 44 | 62 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | P24268 | 407 | CATD_RAT Cathepsin D OS=Rattus norvegicus (Ra... | 349 | 4e-93 | 292 | 44 | 63 | GO:0005764; C:lysosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD. | | | | | | | | | | GO:0006914; P:autophagy; IEP:RGD.::GO:0006508; P:proteolysis; IDA:RGD. | 15 | Q4LAL9 | 410 | CATD_CANFA Cathepsin D OS=Canis familiaris (D... | 342 | 8e-93 | 291 | 44 | 62 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | P80209 | 390 | CATD_BOVIN Cathepsin D OS=Bos taurus (Bovine)... | 342 | 2e-92 | 289 | 44 | 62 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | O96009 | 420 | NAPSA_HUMAN Napsin-A OS=Homo sapiens (Human).... | 366 | 4e-92 | 290 | 41 | 61 | GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0042599; C:lamellar body; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.::GO:0043129; P:surfactant homeostasis; IDA:UniProtKB. | 18 | P18242 | 410 | CATD_MOUSE Cathepsin D OS=Mus musculus (Mouse... | 352 | 7e-90 | 283 | 42 | 61 | GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:MGI. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:MGI.::GO:0006508; P:proteolysis; IC:MGI. | 19 | O76856 | 383 | CATD_DICDI Cathepsin D OS=Dictyostelium disco... | 344 | 2e-89 | 281 | 44 | 61 | GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 20 | Q9GMY4 | 389 | PEPC_SORUN Gastricsin OS=Sorex unguiculatus (... | 396 | 3e-87 | 276 | 38 | 57 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | Q9MZS8 | 365 | CATD_SHEEP Cathepsin D OS=Ovis aries (Sheep).... | 325 | 7e-87 | 274 | 44 | 62 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 22 | P70269 | 397 | CATE_MOUSE Cathepsin E OS=Mus musculus (Mouse... | 380 | 1e-86 | 275 | 40 | 57 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:MGI. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 23 | Q805F3 | 397 | CATEA_XENLA Cathepsin E-A OS=Xenopus laevis (... | 322 | 2e-86 | 274 | 41 | 61 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 24 | P81498 | 389 | PEPC_SUNMU Gastricsin OS=Suncus murinus (Asia... | 397 | 5e-86 | 273 | 37 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 25 | Q805F2 | 397 | CATEB_XENLA Cathepsin E-B OS=Xenopus laevis (... | 322 | 7e-86 | 273 | 42 | 60 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 26 | P55956 | 398 | ASP3_CAEEL Aspartic protease 3 OS=Caenorhabdi... | 335 | 8e-86 | 273 | 41 | 60 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 27 | P00795 | 345 | CATD_PIG Cathepsin D OS=Sus scrofa (Pig). GN=... | 343 | 3e-85 | 270 | 43 | 61 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | P16228 | 398 | CATE_RAT Cathepsin E OS=Rattus norvegicus (Ra... | 379 | 9e-85 | 270 | 39 | 57 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 29 | Q9N2D3 | 388 | PEPC_CALJA Gastricsin OS=Callithrix jacchus (... | 398 | 2e-84 | 269 | 36 | 57 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | P20142 | 388 | PEPC_HUMAN Gastricsin OS=Homo sapiens (Human)... | 320 | 3e-84 | 268 | 41 | 61 | GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; TAS:ProtInc. | 31 | P14091 | 401 | CATE_HUMAN Cathepsin E OS=Homo sapiens (Human... | 396 | 5e-84 | 268 | 37 | 57 | GO:0005768; C:endosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
