| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q69IF8 | 406 | PEPA_PHANO Aspartic protease PEP1 OS=(Glume b... | 371 | 7e-18 | 88.2 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 152 | Q06902 | 404 | PEPA_ASPOR Aspartic protease pep1 OS=Aspergil... | 355 | 8e-18 | 87.8 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 153 | B8NLY9 | 404 | PEPA_ASPFN Aspartic protease pep1 OS=12722 / ... | 355 | 8e-18 | 87.8 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 154 | Q9JL18 | 514 | BACE2_MOUSE Beta-secretase 2 OS=Mus musculus ... | 295 | 1e-17 | 87.8 | 26 | 48 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB. | 155 | Q9Y5Z0 | 518 | BACE2_HUMAN Beta-secretase 2 OS=Homo sapiens ... | 234 | 2e-17 | 87 | 27 | 50 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; IMP:UniProtKB.::GO:0016486; P:peptide hormone processing; NAS:UniProtKB. | 156 | P17946 | 394 | PEPA_ASPAW Aspartic protease pep1 OS=Aspergil... | 347 | 2e-17 | 86.7 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 157 | P53379 | 596 | MKC7_YEAST Aspartic proteinase MKC7 OS=Saccha... | 56 | 0.0006 | 45.4 | 43 | 63 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0006508; P:proteolysis; IMP:SGD. | 158 | P12630 | 587 | BAR1_YEAST Barrierpepsin OS=Saccharomyces cer... | 362 | 3e-17 | 87 | 26 | 42 | GO:0030287; C:cell wall-bounded periplasmic space; TAS:SGD.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IDA:SGD.::GO:0043171; P:peptide catabolic process; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 159 | A2R3L3 | 394 | PEPA_ASPNC Aspartic protease pep1 OS=Aspergil... | 356 | 8e-17 | 85.1 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 160 | C5FZ57 | 430 | Y7979_ARTOC Putative aspergillopepsin A-like ... | 338 | 2e-16 | 84.3 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 161 | E5A7T3 | 409 | PEPA_LEPMJ Aspartic protease PEP1 OS=Av1-4-5-... | 397 | 2e-16 | 83.6 | 27 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 162 | P32834 | 533 | SXA1_SCHPO Aspartic proteinase sxa1 OS=Schizo... | 381 | 3e-16 | 84 | 25 | 41 | GO:0009986; C:cell surface; TAS:PomBase.::GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:PomBase. | | | | | | | | | | GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 163 | P00798 | 323 | PENP_PENJA Penicillopepsin OS=Penicillium jan... | 326 | 7e-16 | 81.3 | 27 | 44 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 164 | C5FRQ0 | 479 | OPSB_ARTOC Probable aspartic-type endopeptida... | 344 | 0.000000000000003 | 80.5 | 26 | 43 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 165 | P56819 | 501 | BACE1_RAT Beta-secretase 1 OS=Rattus norvegic... | 242 | 0.00000000000001 | 79.3 | 26 | 48 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 166 | B8MF81 | 387 | PEPA_TALSN Aspartic protease pep1 OS=NRRL 100... | 308 | 0.00000000000001 | 78.6 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 167 | Q4WZS3 | 428 | Y5950_ASPFU Putative aspergillopepsin A-like ... | 333 | 0.00000000000001 | 78.6 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 168 | P56817 | 501 | BACE1_HUMAN Beta-secretase 1 OS=Homo sapiens ... | 242 | 0.00000000000002 | 78.6 | 26 | 48 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0008798; F:beta-aspartyl-peptidase activity; TAS:ProtInc.::GO:0019899; F:enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; TAS:UniProtKB. | 169 | P56818 | 501 | BACE1_MOUSE Beta-secretase 1 OS=Mus musculus ... | 242 | 0.00000000000002 | 78.2 | 26 | 48 | GO:0030424; C:axon; IDA:MGI.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 170 | D4DGR1 | 430 | Y6366_TRIVH Probable aspartic-type endopeptid... | 237 | 0.00000000000005 | 76.6 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 171 | Q2HJ40 | 501 | BACE1_BOVIN Beta-secretase 1 OS=Bos taurus (B... | 242 | 0.00000000000006 | 76.6 | 26 | 48 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 172 | D4DE18 | 401 | Y5382_TRIVH Probable aspartic-type endopeptid... | 390 | 0.00000000000009 | 75.9 | 24 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 173 | D4AT39 | 430 | Y7403_ARTBC Probable aspartic-type endopeptid... | 237 | 0.0000000000001 | 75.9 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 174 | P40583 | 537 | YPS6_YEAST Aspartic proteinase yapsin-6 OS=Sa... | 384 | 0.0000000000004 | 74.3 | 23 | 42 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 175 | Q4WFS2 | 439 | Y1220_ASPFU Probable aspartic-type endopeptid... | 361 | 0.0000000000005 | 73.9 | 24 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 176 | P11838 | 419 | CARP_CRYPA Endothiapepsin OS=parasitica). GN=... | 320 | 0.0000000000006 | 73.6 | 28 | 41 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 177 | Q1KLR6 | 473 | BACE1_CAVPO Beta-secretase 1 OS=Cavia porcell... | 233 | 0.000000000002 | 72 | 25 | 45 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 178 | C5PEI9 | 443 | PEPA_COCP7 Aspartic protease PEP3 OS=Coccidio... | 270 | 0.000000000003 | 71.6 | 29 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 179 | D4D7C5 | 403 | PEPA_TRIVH Aspartic endopeptidase PEP1 OS=Tri... | 332 | 0.000000000003 | 71.2 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 180 | E5R1B9 | 403 | PEPA_ARTGP Aspartic protease PEP1 OS=gypseum)... | 350 | 0.00000000002 | 68.9 | 25 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 181 | C5FW52 | 388 | Y6955_ARTOC Probable aspartic-type endopeptid... | 339 | 0.00000000002 | 68.6 | 24 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
