| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08023 | 583 | FMP25_YEAST Protein FMP25, mitochondrial OS=S... | 446 | 3e-25 | 113 | 24 | 41 | GO:0031305; C:integral to mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0034551; P:mitochondrial respiratory chain complex III assembly; IMP:SGD. | 2 | Q6PAV2 | 1057 | HERC4_MOUSE Probable E3 ubiquitin-protein lig... | 411 | 0.00000003 | 60.5 | 25 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 3 | Q5PQN1 | 1057 | HERC4_RAT Probable E3 ubiquitin-protein ligas... | 411 | 0.0000001 | 58.5 | 24 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 4 | Q8IVU3 | 1022 | HERC6_HUMAN Probable E3 ubiquitin-protein lig... | 231 | 1 | 36.2 | 26 | 42 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 5 | Q5GLZ8 | 1057 | HERC4_HUMAN Probable E3 ubiquitin-protein lig... | 415 | 0.0000005 | 56.6 | 24 | 38 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 6 | Q3MHW0 | 464 | SRGEF_BOVIN Secretion-regulating guanine nucl... | 88 | 0.26 | 37.7 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q9UII4 | 1024 | HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS... | 212 | 0.74 | 36.6 | 24 | 36 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 8 | Q6P798 | 551 | RCBT2_RAT RCC1 and BTB domain-containing prot... | 231 | 0.0000002 | 57.8 | 26 | 38 | | | | | | | | | | | | | | | | | | | | | | 9 | Q15034 | 1050 | HERC3_HUMAN Probable E3 ubiquitin-protein lig... | 249 | 0.017 | 42 | 25 | 37 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 10 | Q99LJ7 | 551 | RCBT2_MOUSE RCC1 and BTB domain-containing pr... | 231 | 0.0000006 | 55.8 | 26 | 38 | | | | | | | | | | | | | | | | | | | | | | 11 | Q5RCZ7 | 551 | RCBT2_PONAB RCC1 and BTB domain-containing pr... | 204 | 0.0000007 | 55.8 | 27 | 40 | | | | | | | | | | | | | | | | | | | | | | 12 | O95199 | 551 | RCBT2_HUMAN RCC1 and BTB domain-containing pr... | 204 | 0.0000007 | 55.8 | 27 | 40 | | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | | 13 | Q8SSY6 | 1887 | SPKUL_DICDI Bifunctional serine/threonine-pro... | 186 | 1.8 | 35.4 | 24 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | P28745 | 539 | RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce... | 275 | 0.000001 | 55.1 | 26 | 41 | GO:0000790; C:nuclear chromatin; NAS:PomBase. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase. | 15 | Q8TD19 | 979 | NEK9_HUMAN Serine/threonine-protein kinase Ne... | 322 | 0.0001 | 49.3 | 20 | 38 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 16 | Q6NXM2 | 531 | RCBT1_MOUSE RCC1 and BTB domain-containing pr... | 281 | 0.00001 | 52 | 26 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | P0C5Y8 | 1651 | ALS2_RAT Alsin OS=Rattus norvegicus (Rat). GN... | 209 | 0.067 | 40 | 25 | 40 | GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:RGD.::GO:0008219; P:cell death; IMP:RGD.::GO:0001701; P:in utero embryonic development; IEP:RGD.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0016601; P:Rac protein signal transduction; IDA:RGD.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB. | 18 | Q9CYF5 | 461 | WBS16_MOUSE Williams-Beuren syndrome chromoso... | 132 | 0.00004 | 49.7 | 27 | 45 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | | 19 | O95714 | 4834 | HERC2_HUMAN E3 ubiquitin-protein ligase HERC2... | 245 | 2.4 | 35 | 24 | 39 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 20 | Q4U2R1 | 4836 | HERC2_MOUSE E3 ubiquitin-protein ligase HERC2... | 282 | 2.4 | 35 | 22 | 36 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI. | 21 | Q86SG6 | 692 | NEK8_HUMAN Serine/threonine-protein kinase Ne... | 313 | 3.5 | 34.3 | 20 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | Q8K1R7 | 984 | NEK9_MOUSE Serine/threonine-protein kinase Ne... | 322 | 0.00007 | 49.7 | 20 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 23 | Q8VE37 | 421 | RCC1_MOUSE Regulator of chromosome condensati... | 192 | 0.000006 | 52.4 | 29 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB. | 24 | Q7ZZC8 | 944 | NEK9_XENLA Serine/threonine-protein kinase Ne... | 273 | 9.9 | 32.7 | 21 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 25 | Q920R0 | 1651 | ALS2_MOUSE Alsin OS=Mus musculus (Mouse). GN=... | 204 | 0.13 | 39.3 | 26 | 42 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0042598; C:vesicular fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001662; P:behavioral fear response; IMP:MGI.::GO:0016197; P:endosome transport; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0008104; P:protein localization; IMP:MGI.::GO:0001881; P:receptor recycling; IMP:MGI.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB.::GO:0032313; P:regulation of Rab GTPase activity; IDA:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016050; P:vesicle organization; IDA:MGI. | 26 | Q80YD6 | 464 | SRGEF_MOUSE Secretion-regulating guanine nucl... | 426 | 0.00001 | 52 | 23 | 36 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | P25183 | 424 | RCC1_XENLA Regulator of chromosome condensati... | 190 | 0.00001 | 51.6 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 28 | Q15751 | 4861 | HERC1_HUMAN Probable E3 ubiquitin-protein lig... | 431 | 4.3 | 34.3 | 20 | 36 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 29 | P18754 | 421 | RCC1_HUMAN Regulator of chromosome condensati... | 191 | 0.00001 | 51.2 | 28 | 41 | GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome. | 30 | P23800 | 421 | RCC1_MESAU Regulator of chromosome condensati... | 192 | 0.00002 | 50.8 | 28 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB. | 31 | Q96Q42 | 1657 | ALS2_HUMAN Alsin OS=Homo sapiens (Human). GN=... | 248 | 0.023 | 41.6 | 25 | 39 | GO:0005813; C:centrosome; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; NAS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:UniProtKB.::GO:0051036; P:regulation of endosome size; IEP:UniProtKB. |
