rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q98936 | 1422 | PTPRG_CHICK Receptor-type tyrosine-protein ph... | 67 | 0.023 | 41.6 | 36 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 62 | Q05909 | 1442 | PTPRG_MOUSE Receptor-type tyrosine-protein ph... | 67 | 0.098 | 39.7 | 34 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 63 | Q64604 | 1898 | PTPRF_RAT Receptor-type tyrosine-protein phos... | 161 | 0.000005 | 53.5 | 34 | 46 | GO:0005768; C:endosome; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:RGD.::GO:0031345; P:negative regulation of cell projection organization; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IMP:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0051387; P:negative regulation of nerve growth factor receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0050803; P:regulation of synapse structure and activity; IMP:RGD. | 64 | P16621 | 2029 | LAR_DROME Tyrosine-protein phosphatase Lar OS... | 97 | 0.0002 | 48.5 | 37 | 52 | GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; IDA:FlyBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0032093; F:SAM domain binding; IPI:FlyBase. | | | | | | | | | | GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; NAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0008594; P:photoreceptor cell morphogenesis; IMP:FlyBase.::GO:0045467; P:R7 cell development; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase. | 65 | A4IFW2 | 1909 | PTPRF_DANRE Receptor-type tyrosine-protein ph... | 98 | 0.00006 | 50.1 | 38 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 66 | Q99M80 | 1454 | PTPRT_MOUSE Receptor-type tyrosine-protein ph... | 152 | 0.027 | 41.6 | 23 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0051393; F:alpha-actinin binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0045296; F:cadherin binding; IPI:MGI.::GO:0070097; F:delta-catenin binding; IPI:MGI.::GO:0045295; F:gamma-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016790; F:thiolester hydrolase activity; IDA:MGI. | | | | | | | | | | | 67 | P29461 | 750 | PTP2_YEAST Tyrosine-protein phosphatase 2 OS=... | 197 | 0.000000009 | 62 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0043937; P:regulation of sporulation; IGI:SGD. | 68 | O14522 | 1441 | PTPRT_HUMAN Receptor-type tyrosine-protein ph... | 152 | 0.029 | 41.2 | 23 | 36 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0045294; F:alpha-catenin binding; IDA:UniProtKB.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045296; F:cadherin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB. | 69 | Q13332 | 1948 | PTPRS_HUMAN Receptor-type tyrosine-protein ph... | 97 | 0.00002 | 52 | 41 | 53 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 70 | P34138 | 377 | PTP2_DICDI Tyrosine-protein phosphatase 2 OS=... | 74 | 0.00007 | 49.3 | 39 | 49 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:dictyBase. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase. | 71 | P26045 | 913 | PTN3_HUMAN Tyrosine-protein phosphatase non-r... | 152 | 0.00000002 | 60.8 | 27 | 41 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051117; F:ATPase binding; IPI:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL. | 72 | P35233 | 416 | PTN2_RAT Tyrosine-protein phosphatase non-rec... | 75 | 0.00000002 | 60.5 | 43 | 57 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | | 73 | Q9WU22 | 926 | PTN4_MOUSE Tyrosine-protein phosphatase non-r... | 121 | 0.0000005 | 56.6 | 31 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | | 74 | A7MBJ4 | 1898 | PTPRF_BOVIN Receptor-type tyrosine-protein ph... | 144 | 0.000007 | 53.1 | 36 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 75 | Q06180 | 406 | PTN2_MOUSE Tyrosine-protein phosphatase non-r... | 72 | 0.00000002 | 60.5 | 42 | 56 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI. | 76 | P17706 | 415 | PTN2_HUMAN Tyrosine-protein phosphatase non-r... | 73 | 0.00000002 | 60.1 | 44 | 58 | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome. | 77 | P20417 | 432 | PTN1_RAT Tyrosine-protein phosphatase non-rec... | 70 | 0.00000006 | 58.9 | 44 | 56 | GO:0031225; C:anchored to membrane; NAS:RGD.::GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IMP:RGD. | 78 | Q9W0G1 | 548 | PTP61_DROME Tyrosine-protein phosphatase non-... | 71 | 0.00000008 | 58.9 | 41 | 61 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005740; C:mitochondrial envelope; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase. | | | | | | | | | | GO:0007411; P:axon guidance; IPI:FlyBase.::GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0007377; P:germ-band extension; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase. | 79 | P70289 | 1705 | PTPRV_MOUSE Receptor-type tyrosine-protein ph... | 139 | 0.0000004 | 57 | 33 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 80 | P29074 | 926 | PTN4_HUMAN Tyrosine-protein phosphatase non-r... | 117 | 0.000004 | 53.5 | 32 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 81 | P18031 | 435 | PTN1_HUMAN Tyrosine-protein phosphatase non-r... | 154 | 0.0000001 | 58.2 | 34 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; NAS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030100; P:regulation of endocytosis; IDA:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 82 | Q99952 | 460 | PTN18_HUMAN Tyrosine-protein phosphatase non-... | 106 | 0.002 | 44.3 | 33 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 83 | P35821 | 432 | PTN1_MOUSE Tyrosine-protein phosphatase non-r... | 70 | 0.00000007 | 58.9 | 44 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB. | 84 | P16620 | 1462 | PTP69_DROME Tyrosine-protein phosphatase 69D ... | 81 | 0.64 | 37 | 28 | 43 | GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007415; P:defasciculation of motor neuron axon; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase. | 85 | Q61152 | 453 | PTN18_MOUSE Tyrosine-protein phosphatase non-... | 105 | 0.002 | 44.7 | 34 | 48 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 86 | Q5I141 | 300 | PTPJ1_MDBVW Tyrosine phosphatase-like protein... | 97 | 0.056 | 39.7 | 27 | 45 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 87 | Q64612 | 1711 | PTPRV_RAT Receptor-type tyrosine-protein phos... | 64 | 0.00002 | 51.6 | 44 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046849; P:bone remodeling; IEP:RGD. | 88 | Q15262 | 1439 | PTPRK_HUMAN Receptor-type tyrosine-protein ph... | 99 | 0.000008 | 52.8 | 37 | 52 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 89 | Q5I146 | 325 | PTPH2_MDBVW Tyrosine phosphatase H2 OS=Microp... | 94 | 0.0002 | 47.4 | 29 | 53 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW. | 90 | P35822 | 1457 | PTPRK_MOUSE Receptor-type tyrosine-protein ph... | 100 | 0.000002 | 55.1 | 39 | 53 | GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 91 | P43378 | 593 | PTN9_HUMAN Tyrosine-protein phosphatase non-r... | 115 | 0.00003 | 50.8 | 34 | 48 | GO:0044444; C:cytoplasmic part; IDA:UniProtKB. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | |